EPIDEMIOLOGY AND NOSOCOMIAL INFECTIONS CHAPTER 15 1 What

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EPIDEMIOLOGY AND NOSOCOMIAL INFECTIONS CHAPTER 15 1

EPIDEMIOLOGY AND NOSOCOMIAL INFECTIONS CHAPTER 15 1

What is Epidemiology? 2

What is Epidemiology? 2

Table 33 -1 3

Table 33 -1 3

Epidemiology n What is Epidemiology? n Etiology n Incidence n Prevalence causation a/a+b 4

Epidemiology n What is Epidemiology? n Etiology n Incidence n Prevalence causation a/a+b 4

Epidemiological Terms n Morbidity n Mortality 5

Epidemiological Terms n Morbidity n Mortality 5

Figure 33 -6 6

Figure 33 -6 6

Diseases in Populations n Endemic n Pandemic n Epidemic n Sporadic 7

Diseases in Populations n Endemic n Pandemic n Epidemic n Sporadic 7

Figure 33 -2 8

Figure 33 -2 8

Incidence Types 9

Incidence Types 9

Disease Spread n Common Source Outbreak n Propagated Epidemic 10

Disease Spread n Common Source Outbreak n Propagated Epidemic 10

Epidemiologic Studies n Descriptive n Analytical n Experimental 11

Epidemiologic Studies n Descriptive n Analytical n Experimental 11

The Basic Triad Of Descriptive Epidemiology THE THREE ESSENTIAL CHARACTERISTICS OF DISEASE WE LOOK

The Basic Triad Of Descriptive Epidemiology THE THREE ESSENTIAL CHARACTERISTICS OF DISEASE WE LOOK FOR IN DESCRIPTIVE EPIDEMIOLOGY: TIME n PLACE n PERSON n 12

Time n Changing or stable? n Seasonal variation. n Clustered (epidemic) or evenly distributed

Time n Changing or stable? n Seasonal variation. n Clustered (epidemic) or evenly distributed (endemic)? n Point source or propagated. 13

Place Geographically restricted or widespread (pandemic)? n Relation to water or food supply. n

Place Geographically restricted or widespread (pandemic)? n Relation to water or food supply. n Multiple clusters or one? n 14

Person n Age n Socio-economic status n Gender n Ethnicity/Race n Behavior 15

Person n Age n Socio-economic status n Gender n Ethnicity/Race n Behavior 15

The Basic Triad Of Analytic Epidemiology THE THREE PHENOMENA ASSESSED IN ANALYTIC EPIDEMIOLOGY ARE:

The Basic Triad Of Analytic Epidemiology THE THREE PHENOMENA ASSESSED IN ANALYTIC EPIDEMIOLOGY ARE: HOST AGENT ENVIRONMENT 16

Agents n n n n Nutrients Poisons Allergens Radiation Physical trauma Microbes Psychological experiences

Agents n n n n Nutrients Poisons Allergens Radiation Physical trauma Microbes Psychological experiences 17

Host Factors Genetic endowment n Immunologic state n n Age n Personal behavior 18

Host Factors Genetic endowment n Immunologic state n n Age n Personal behavior 18

Environment Crowding n Atmosphere n Modes of communication – phenomena in the environment that

Environment Crowding n Atmosphere n Modes of communication – phenomena in the environment that bring host and agent together, such as: n – Vector – Vehicle – Reservoir 19

Infection Reservoirs n Human n Animal n Non-living 20

Infection Reservoirs n Human n Animal n Non-living 20

Microbe Spread n Portals of Entry 21

Microbe Spread n Portals of Entry 21

Microbe Spread n Portals of Exit 22

Microbe Spread n Portals of Exit 22

Modes of Disease Transmission n Contact n Vehicles n Vectors 23

Modes of Disease Transmission n Contact n Vehicles n Vectors 23

Problems in Disease Transmission Disease Cycles n Herd Immunity n 24

Problems in Disease Transmission Disease Cycles n Herd Immunity n 24

Controlling Disease Transmission n Biosafety 25

Controlling Disease Transmission n Biosafety 25

Public Health Organizations n Center for Disease Control (CDC) n World Health Organization (WHO)

Public Health Organizations n Center for Disease Control (CDC) n World Health Organization (WHO) 26

Notifiable Diseases n Definition: n Nationally Notifiable Infectious Diseases 27

Notifiable Diseases n Definition: n Nationally Notifiable Infectious Diseases 27

Nosocomial Infections n Sources 28

Nosocomial Infections n Sources 28

Nosocomial Infection Risks Susceptibility n Transmission n Universal Precautions n 29

Nosocomial Infection Risks Susceptibility n Transmission n Universal Precautions n 29

Figure 33 -9 Other 17% Surgical site infections 22% Pneumonia 15% Bloodstream infections 14%

Figure 33 -9 Other 17% Surgical site infections 22% Pneumonia 15% Bloodstream infections 14% Urinary tract infections 32% 30

Risks Equipment/Procedures n Sites of Infection n 31

Risks Equipment/Procedures n Sites of Infection n 31

Bioterrorism 32

Bioterrorism 32

Anthrax 33

Anthrax 33

Smallpox 34

Smallpox 34