Weak forces in Evolution Dan Graur 1 t
- Slides: 35
Weak forces in Evolution Dan Graur 1
t. nt. a t r o p m i e r sa e i. t. c t n n a e t u r q o e p r f m i e l o e ts all o n n i e s r e a g s n e a i h c n C e u q e r f e p y t no e g n i s e g n a Ch 1. 2. 2
Mating 3
Deviation from randomness: By genetic similarity: Assortative mating Disassortative mating By genetic relatedness: Inbreeding Outbreeding 4
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disassortative 6
Human assortative mating: Rule #1 7
Strong assortative mating by skin color in the US Percentage of non-hispanic whites: 80% Percentage of blacks: 13% Expected percentage of interracial marriages: 10. 4% Observed percentage of interracial marriages: 0. 9% Ratio of white female/black male = 2: 1 black female/white male 8
Assortative mating is very strong in humans even with respect to non-genetic traits. 9
Degrees of inbreeding found in nature: 10
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Inbreeding is usually forbidden… P = Ptolemy C = Cleopatra P ix Cv P xii C vii An exception! 12
The fish Rivulus marmoratus exhibits the most extreme form of inbreeding: Selfing 13
Random mating equilibrium allele frequencies 14
Assortative mating excess homozygotes 15
Disassortative mating excess heterozygotes 16
Even if extreme deviations from random mating occur in all generations, allele frequencies remain constant. 17
Mating pattern is not an important evolutionary force 18
Clinical effects of inbreeding P. T. Barnum + Tom Thumb 19
Clinical effects of inbreeding 20
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Migration 22
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Migration will cause changes in the allele frequencies of each of the two subpopulations. 24
However, because of gene flow, the two subpopulations are, in fact, one population, in which allele frequencies do no change. 25
Genotype frequencies will change in a similar fashion to that in disassortative mating. 26
Migration is not an important evolutionary force 27
Mutation: A transmissible change in the genetic material 28
Mutations are the ultimate source of variation. Only mutations can create genetic novelty. 29
Mutations arise all the time. Per definition, the initial frequency of a mutation in a diploid * population is 1/2 N. *N = population size 30
The human population on October 31, 2011 was estimated to be 7 billion people. The number of alleles at an autosomal locus is, therefore, 14 billion. A mutation arising today in the human population will have an initial frequency of about 7 -11 × 10 … …resulting in a change in allele frequencies from 0 to 0. 000007. 31
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Mutation is the ultimate source of variability, but it is not an important evolutionary force. 33
For a mutation to become significant, it must increase its frequency, so that it * becomes fixed in the population. *frequency of allele = 1. 0 34
Two factors can lead to the fixation of a new mutation: Selection Random genetic drift 35
- Difference between strong and weak acid
- Weak acid and weak base reaction
- Strong acid examples
- 4 forces of evolution
- Unlike parallel force example
- The forces shown above are pushing/pulling forces
- Intramolecular vs intermolecular bonds
- Intermolecular forces ranked
- Covalent bond intermolecular forces
- What are some contact forces and some noncontact forces?
- Net force
- Constructive and destructive forces
- Latar belakang partial participation
- Pengertian entity
- Your my strength when i am weak
- H3po4
- It is a poetic foot that has a pattern of weak
- Weak forms exercises
- Weak entity example
- Weak entity sets
- Strong ai vs weak ai
- Discriminator in weak entity set
- Manth
- Weak electrolyte examples
- Strong acid strong base titration curve
- Multivalued attribute
- Crow foot notation weak entity
- "ben tennant"
- Weak sustainability
- Weak sustainability
- Weak host model
- Weak and strong syllables examples
- Coxa valga angle
- Discriminator in weak entity set
- Weak semaphore
- Ph 3 acid or base