Cellular and extra cellular lesions II Steatosis fatty

Steatosis (fatty change) From: Stevens A. J Lowe J. Pathology. Mosby 1995 Fig. 4.

Hepatic steatosis Fig. 4. 2. Fatty liver is enlarged and yellow

Hepatic steatosis From cases of the Pathology Department - U. M. F. “Gr. T.

Fig. 4. 4 Fig. 4. 3 -4. Fatty liver. Small and large unstained fat

Fig. 4. 6. Fig. 6. Black Sudan: intracellular lipid deposits are black stained

Localized hemosiderosis From cases of the Pathology Department - U. M. F. “Gr. T.

Fig. 4. 8. Fig. 8. In Perls reaction, hemosiderin is blue in color.

Jaundice From: Stevens A. J Lowe J. Pathology. Mosby 1995 Fig. 4. 9. Fig.

Fig. 4. 10. Fig. 10. In icterus, liver is greenish-yellow.

Jaundice From cases of the Pathology Department - U. M. F. “Gr. T. Popa”

Fig. 4. 12. Fig. 11 -12. In hepatic icterus: (a) intrahepatocyte granular pigment hepatocyte

Hyalinosis of afferent glomerular arteriole From: Stevens A. J Lowe J. Pathology. Mosby 199

Fig. 4. 14. From cases of the Pathology Department - U. M. F. “Gr.

Amyloidosis From: Stevens A. J Lowe J. Pathology. Mosby 1995 Fig. 4. 15.

Histology of renal amyloidosis From: Stevens A. J Lowe J. Pathology. Mosby 1995 Fig.

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Cellular and extra cellular lesions II

Steatosis (fatty change) From: Stevens A. J Lowe J. Pathology. Mosby 1995 Fig. 4. 1 Causes of fatty change: diabete, malnutrition, toxic substances (alcohol), chronic hypoxia, over-feeding, etc. Cell poison (alcohol)=>reduced cell enzyme activity=>inability to metabolise fat=>fat cell accumulation

Hepatic steatosis Fig. 4. 2. Fatty liver is enlarged and yellow

Hepatic steatosis From cases of the Pathology Department - U. M. F. “Gr. T. Popa” Iasi Fig. 4. 3

Fig. 4. 4 Fig. 4. 3 -4. Fatty liver. Small and large unstained fat intracellular vacuoles with clear borders.

Hepatic steatosis From cases of the Pathology Department - U. M. F. “Gr. T. Popa” Iasi Fig. 4. 5. Fig. 5. Fatty liver – HE: small and large clear vacuoles.

Fig. 4. 6. Fig. 6. Black Sudan: intracellular lipid deposits are black stained

Localized hemosiderosis From cases of the Pathology Department - U. M. F. “Gr. T. Popa” Iasi Fig. 4. 7 Fig. 7 HE-hemosiderin appears as a yellow brown granular pigment

Fig. 4. 8. Fig. 8. In Perls reaction, hemosiderin is blue in color.

Jaundice From: Stevens A. J Lowe J. Pathology. Mosby 1995 Fig. 4. 9. Fig. 9. Icterus: yelow color of skin and sclerae.

Fig. 4. 10. Fig. 10. In icterus, liver is greenish-yellow.

Jaundice From cases of the Pathology Department - U. M. F. “Gr. T. Popa” Iasi Fig. 4. 11.

Fig. 4. 12. Fig. 11 -12. In hepatic icterus: (a) intrahepatocyte granular pigment hepatocyte cytoplasm contains bilirubin as small greenish-brown granules. (b) billiary cylinder (billiary thrombi) - small biliary channels are distended through greenish-brown pigment; is a characteristic feature in cholestatic jaundice.

Hyalinosis of afferent glomerular arteriole From: Stevens A. J Lowe J. Pathology. Mosby 199 Fig. 4. 13.

Fig. 4. 14. From cases of the Pathology Department - U. M. F. “Gr. T. Popa” Iasi Fig. 13 -14. Afferent arteriole wall hyalinosis, partial or total hyalinosis of glomeruli, and dilated renal tubules with hyaline plugs (thyroidization).

Amyloidosis From: Stevens A. J Lowe J. Pathology. Mosby 1995 Fig. 4. 15.

Fig. 4. 16.

Histology of renal amyloidosis From: Stevens A. J Lowe J. Pathology. Mosby 1995 Fig. 4. 17.

Fig. 4. 18.