Holes Human Anatomy and Physiology Eleventh Edition Shier

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Hole’s Human Anatomy and Physiology Eleventh Edition Shier w Butler w Lewis Chapter 22

Hole’s Human Anatomy and Physiology Eleventh Edition Shier w Butler w Lewis Chapter 22 Copyright © The Mc. Graw-Hill Companies, Inc. Permission required for reproduction or display. 1

Male Reproductive System • Primary sex organ (gonads) • testes • Accessory sex organs:

Male Reproductive System • Primary sex organ (gonads) • testes • Accessory sex organs: • Epididymis • Ductus deferentia – aka vas deferens • Seminal vesicles • Prostate gland • Bulbourethral gland • Scrotum • Penis 2

Testes • Suspended by spermatic cord • Within saclike structure called the scrotum posterior

Testes • Suspended by spermatic cord • Within saclike structure called the scrotum posterior view • Develop in same area of kidneys but descend through inguinal canal before birth • Green box p. 850 • Cryptorchidism • Inguinal hernia • Strangulated hernia 3

Structure of the Testes • Constructed of seminiferous tubules • Seminiferous tubules lined with

Structure of the Testes • Constructed of seminiferous tubules • Seminiferous tubules lined with epithelium from which sperm is made • Interstitial cells are between seminiferous tubules and secrete male hormones • P. 851 Testicular cancer 4

Formation of Sperm Cells Spermatogonia in seminiferous tubules undergo meiosis to produce sperm 5

Formation of Sperm Cells Spermatogonia in seminiferous tubules undergo meiosis to produce sperm 5

Spermatogenesis Through meiosis one primary spermatocyte will produce 4 sperm cells. 6

Spermatogenesis Through meiosis one primary spermatocyte will produce 4 sperm cells. 6

Structure of a Sperm Cell Three Regions 1. Head • Acrosome – enzymes that

Structure of a Sperm Cell Three Regions 1. Head • Acrosome – enzymes that aid in penetration of egg • Nucleus – contains 23 chromosomes 2. Midpiece – contains mitochodria which produce energy needed for sperm to move 3. Tail – flagellum used for movement 7

Leeuwenhoek’s idea of sperm Actual Sperm 8

Leeuwenhoek’s idea of sperm Actual Sperm 8

Epididymides • tightly coiled tubes • connected to ducts within testis • secretes substances

Epididymides • tightly coiled tubes • connected to ducts within testis • secretes substances that promote maturation of sperm cells • Immature sperm stored there until they reach maturation 9

Ductus Deferentia • Aka vas deferens • muscular tubes • about 45 cm each

Ductus Deferentia • Aka vas deferens • muscular tubes • about 45 cm each • extends from epididymis to ejaculatory duct which is the tube that leads into the urethra • Functions is to carry sperm from epididymis to urethra 10

Seminal Vesicles • attached to vas deferens near base of bladder • secrete alkaline

Seminal Vesicles • attached to vas deferens near base of bladder • secrete alkaline fluid which regulates p. H needed for sperm • • secretes fructose which sperm use for energy • Secretes prostaglandins that cause muscular contractions within female reproductive organs • contents empty into ejaculatory duct 11

Prostate Gland • surrounds proximal portion of urethra • ducts of gland open into

Prostate Gland • surrounds proximal portion of urethra • ducts of gland open into urethra • secretes a thin, milky, alkaline fluid • • secretion enhances mobility of sperm and sustain them by neutralizing acidic conditions both from sperm themselves and within female reproductive system • P. 858 Clinical Application: Enlarged Protate 12

Study links finger length to prostate cancer risk http: //www. msnbc. msn. com/id/40442341/ns/health-cancer/ LONDON

Study links finger length to prostate cancer risk http: //www. msnbc. msn. com/id/40442341/ns/health-cancer/ LONDON — Men with long index fingers have a lower risk of prostate cancer, British scientists said on Wednesday, a finding that could be used to help select those who need regular screening for the disease. More likely Less likely 13

Bulbourethral Glands • Aka Cowper’s gland • inferior to the prostate gland • secrete

Bulbourethral Glands • Aka Cowper’s gland • inferior to the prostate gland • secrete mucus-like fluid • fluid released in response to sexual stimulation 14

Semen • Includes • sperm cells • secretions of seminal vesicles, prostate gland, and

Semen • Includes • sperm cells • secretions of seminal vesicles, prostate gland, and bulbourethral glands • slightly alkaline – p. H approximately 7. 5 • 120 million sperm cells per milliliter • Sperm live for weeks in testes but only about 3 days (72 hours) outside of male body 15

 • Scrotum • pouch of skin and subcutaneous tissue • dartos muscle •

• Scrotum • pouch of skin and subcutaneous tissue • dartos muscle • smooth muscle in subcutaneous tissue • Helps maintain optimal temperature for sperm by moving testes closer or further away from body • medial septum divides scrotum into two chambers • each chamber houses a testis and epididymis 16

Penis • conveys urine and semen to outside of body • specialized tissue designed

Penis • conveys urine and semen to outside of body • specialized tissue designed to become erect for insertion into the vagina 17

Penis • Consists of 3 layers of tissue • Urethra extends through • Distal

Penis • Consists of 3 layers of tissue • Urethra extends through • Distal end forms glans penis where urethral opening is found • Contain pairs of arteries, veins, and nerves • Circumcision – prepuce (foreskin) is removed 18

Hormonal Control of Male Reproductive Functions • hypothalamus releases gonadotropin-releasing hormone (Gn. RH) •

Hormonal Control of Male Reproductive Functions • hypothalamus releases gonadotropin-releasing hormone (Gn. RH) • Gn. RH stimulates the anterior pituitary to produce gonadotropins (LH and FSH) 19

LH and FSH • FSH – follical stimulating hormone stimulates spermatocytes to produce sperm

LH and FSH • FSH – follical stimulating hormone stimulates spermatocytes to produce sperm • LH – luteinizing hormone stimulates interstitial cells to produce androgens (male hormones) 20

Actions of Testosterone The androgen testosterone is responsible for secondary sex characteristics. • increased

Actions of Testosterone The androgen testosterone is responsible for secondary sex characteristics. • increased growth of body hair • sometimes decreased growth of scalp hair • enlargement of larynx and thickening of vocal cords • thickening of skin • increased muscular growth • thickening and strengthening of the bones 21

Hormone Regulation • Hormone levels are regulated by a negative feedback system between the

Hormone Regulation • Hormone levels are regulated by a negative feedback system between the hypotalamus, anterior pituitary, and testes. • Levels increase with puberty (begins around age 10) 22

Female Reproductive System • Primary sex organ (gonads) • ovaries • Accessory sex organs:

Female Reproductive System • Primary sex organ (gonads) • ovaries • Accessory sex organs: • Uterine tubes (fallopian tubes) • Uterus • Vagina 23

Ovary Attachments Ovaries and uterus are held in place by ligaments. 24

Ovary Attachments Ovaries and uterus are held in place by ligaments. 24

Primordial Follicles • Females are born with approximately 1 million primordial oocytes. • At

Primordial Follicles • Females are born with approximately 1 million primordial oocytes. • At puberty these begin to develop and be released one per month. 25

Oogenesis • beginning at puberty primary oocytes undergo meiosis • Results in one secondary

Oogenesis • beginning at puberty primary oocytes undergo meiosis • Results in one secondary oocyte • Unequal division of the cytoplasm results in development of polar bodies which degenerate 26

Follicle Maturation Primordial follicle Mature (Graafian) follicle • Egg matures in a fluid filled,

Follicle Maturation Primordial follicle Mature (Graafian) follicle • Egg matures in a fluid filled, blister-like follicle • Maturation of a follical takes about 10 -14 days. 27

Follicle Maturation Several follicles will be maturing at the same time just at different

Follicle Maturation Several follicles will be maturing at the same time just at different rates. 28

Ovulation • Wall of follicle ruptures releasing the oocyte. • Green box P. 870

Ovulation • Wall of follicle ruptures releasing the oocyte. • Green box P. 870 Clomid 29

Ovulation 30

Ovulation 30

Uterine Tubes aka Fallopian Tubes • About 10 cm long • convey eggs toward

Uterine Tubes aka Fallopian Tubes • About 10 cm long • convey eggs toward the uterus • Fingerlike projections called fimbriae direct egg into tube • Lining has cilia that help move egg downward 31

Lining of Uterine Tubes 32

Lining of Uterine Tubes 32

Uterus aka Womb • hollow muscular organ that receives the embryo that has been

Uterus aka Womb • hollow muscular organ that receives the embryo that has been fertilized in the uterine tube • End of uterus that opens into vagina is called the cervix 33

Cervix • Pap Smear is a test to check the cells of the cervix

Cervix • Pap Smear is a test to check the cells of the cervix for any abnormality that might lead to or indicate cervical cancer • HPV – human papilloma virus leading cause of cervical cancer 34

Uterine Wall 3 layers 1. Endometrium – mucosal layer 2. Myometrium – smooth muscle

Uterine Wall 3 layers 1. Endometrium – mucosal layer 2. Myometrium – smooth muscle layer 3. Perimetrium – serosa layer 35

Vagina aka Birth Canal • fibromuscular tube that conveys uterine secretions, receives the penis

Vagina aka Birth Canal • fibromuscular tube that conveys uterine secretions, receives the penis during intercourse, and provides an open channel for offspring • Opening from outside is partially covered by hymen – a membrane 36

Hormonal Control of Female Reproductive Functions • estrogens inhibit LH and FSH during most

Hormonal Control of Female Reproductive Functions • estrogens inhibit LH and FSH during most of the reproductive cycle • Birth control pills work because they are synthetic forms of estrogen and progesterone 37

Effects of Estrogens • development of breasts and ductile system of the mammary glands

Effects of Estrogens • development of breasts and ductile system of the mammary glands • increased adipose tissue in breasts, thighs, and buttocks • increases vascularization of skin • Body hair growth is due to androgens that increase at puberty 38

Female Reproductive Cycle • Like in the male, the hypothalamus secretes Gn. RH •

Female Reproductive Cycle • Like in the male, the hypothalamus secretes Gn. RH • Gn. RH stimulates the anterior pituitary to produce LH and FSH • FSH stimulates a follicle to develop 39

Female Reproductive Cycle • The follicle produces some estrogen • LH stimulates cells within

Female Reproductive Cycle • The follicle produces some estrogen • LH stimulates cells within the ovary to produce estrogen precursors • As a result of increasing estrogen levels the endometrium thickens 40

Female Reproductive Cycle • A spike in hormone levels (LH and FSH) during mid-cycle

Female Reproductive Cycle • A spike in hormone levels (LH and FSH) during mid-cycle will cause ovulation to occur (egg released) • The leftover follicle, corpus luteum, secretes an increased level of progesterone. 41

Female Reproductive Cycle • Progesterone causes the endometrium to become more vascular. • If

Female Reproductive Cycle • Progesterone causes the endometrium to become more vascular. • If pregnancy does NOT occur the corpus luteum dries up and the hormone levels drop drastically • As a result of the drop in hormone levels the endometrium is shed 42

Menopause • usually occurs in late 40 s or early 50 s • reproductive

Menopause • usually occurs in late 40 s or early 50 s • reproductive cycles stop • ovaries no longer produce as much estrogens and progesterone • some female secondary sex characteristics may disappear • may produce hot flashes and fatigue • hormone therapy may prevent effects on bone tissue 43

Mammary Glands • located in the subcutaneous tissue of the anterior thorax within the

Mammary Glands • located in the subcutaneous tissue of the anterior thorax within the breasts • composed of lobes • estrogens stimulate breast development in females 44

Birth Control • coitus interruptus • rhythm method • mechanical barriers • condom •

Birth Control • coitus interruptus • rhythm method • mechanical barriers • condom • diaphragm • cervical cap • spermicidal foams or jellies • chemical barriers • spermicides • oral contraceptives • hormonal • injectable contraception • hormonal • intrauterine devices • surgical methods • vasectomy • tubal ligation 45

Surgical Methods of Birth Control Vasectomy Tubal ligation 46

Surgical Methods of Birth Control Vasectomy Tubal ligation 46