Digestive tract Liver Pancreas GYTK 2018 03 19

Digestive tract Liver Pancreas GYTK 2018. 03. 19. Dr. Szuák András

The great glands • Liver • Pancreas

Right coronary lig. Left coronary lig. Right lobe Left lobe Falciform lig Gall bladder

Ligamentum venosum Caudate lobe Inferior vena cava Bare area Left lobe Hepatorenal lig. Liver hilum Portal vein Hepatic duct Proper hepatic artery Round lig. Gall bladder Right lobe

Segments of the liver

Lobes of the liver • The actual boarder is the so called Rex-Cantlie line – Line between • inferior vena cava • gall bladder

Diaphragm Topography of the liver Left coronary lig. Falciform lig. Round lig. Liver Spleen Stomach Gall bladder Hepatoduodenal lig. Lesser omentum Right colic flexure Left colic flexure Transverse mesocolon Transverse colon Descending colon Ascending colon Greater omentum

Hepatoduodenal lig. Hepatogastric lig. Omental bursa Greater omentum L e s s e r o m e n t u m

Bile passages Cystic duct Bile duct Duodenum Hepatic duct Pancreatic duct

Blood supply of the liver

Portal vein

Histology of the liver • Hepatic lobules – hexagonal shape (portal lobule, acinus) – Portal triad – portal vein, artery, bile duct – Hepatic sinusoids between the hepatic chords – Central vein

Hepatic lobule Central vein Hep. sinus Hep. chord Interlobular vein Interlobular artery Portal triad Interlobular duct

Hepatic sinus

Bile canaliculi

Portal triad Central vein

Interlobular duct Interlobular artery Interlobular vein Portal triad

Endothel cell Kupffer-cell Hep. chord Bile canaliculus

Gall bladder • • • Simple columnar epith. Lamina propria – glands, lymphocytes NO Muscularis mucosae layer NO Submucosa layer Muscularis externa – cirlular, longitudinal and oblique layers • Serosa OR Adventitia

Gall bladder

The great glands • Liver • Pancreas

Pancreas

Ducts opening into the duodenum Right hepatic duct Cystic duct Gall bladder Bile duct Minor duodenal papilla Major duodenal papilla Left hepatic duct Common hepatic duct Accessory pancreatic duct Pancreatic duct

Blood supply of the pancreas

Histology of the pancreas • Serous gland • Centroaciner cell • Langerhans islets – endocrine part

Kidney Urinary tract

Position of the kidneys

Kidney Adrenal gland Renal artery Renal vein Ureter Fibrous capsule Adipose capsule

cortex medulla

Kidney • Medulla – pyramids – Renal lobes • Cortex – Bertini columns – Convoluted part – Straight part • Renal artery – interlobar aa. –arcuate aa. – interlobular aa.

Nephron

Nephron

Macula densa Malphigian corpuscule Podocytes interdigitating

Ureter • Urothelium • Dense fibro-elastic connective tissue in the lamina propria • NO muscularis mucosae&submucosa • Muscularis externa – Inner longitudinal, outer circular layer – Serosa or Adventitia

Urinary bladder • Urothelium • Dense fibro-elastic connective tissue in the lamina propria • Muscularis mucosae – Not forming a continous layer, only some islets of smooth muscle • Submucosa – loose connective tissue • Muscularis externa – Inner&outer longitudinal layers, middle circular layer • Serosa or Adventitia

Urothelium, umbrella cells

Male Bladder&Urethra

Female Bladder&Urethra

Thank you for your attention!