Ice Power cold therapy Effective and safe non

Ice Power cold therapy Effective and safe non medicine pain relief

Topics • • Physiological effect of cold Ice Power cold gel Proven efficacy How to use Ice Power

Physiological effects of cold Reduces the pain sensation Reduces swelling and bleeding Cold Stimulates person’s own opioid production Prevents inflammation What does it do in a human body? Reduces muscle spasms and tensions Decreases metabolic rate

Physiological effects of cold - how cold effects to pain Pain and temperature information travels to the brain and back via spinal cord. For example, tissue damage activates the nociceptors to send signals by peripheral nerves through spinal cord to the brain. Cold therapy activates thermoreceptors to transmit the sensation of cold the same route as the nociceptors send signals of pain. After data has been processed in the brain, pain becomes more controlled.

Benefits of cold therapy - why to use cold ? • • Very effective non medicine pain relief Immediate response No contraindications (excl. cold urticaria) Safe to use at all ages Complications after long time of using ice • Frost bites and nerve injuries Cold therapy methods • Ice, cold water, ice packs, cold gels Cold therapy is one of the oldest way to manage pain!

Ice Power cold gel

Ice Power cold gel – easy and safe way to manage pain Unique cold gel formulation for fast and effective pain relief Invented and manufactured in Finland Most sold cold therapy product line in Finland for over 20 years in phamacies • Belongs into the EU medical supplies class 1, under supervision of National Agency for Medicines, CE-marked. • Ice Power is the only cold gel in the world which has scientific proven efficacy How does it work? • Cold effect comes from menthol, eucalyptus oil and ethanol, unique formulation! • • •

Benefits of using Ice Power cold gels • • Allows continous and effect pain treatment, anytime and anywhere. Immediate, concrete and long lasting effect. Allows long term effective cold treatment -> makes pain sensation more tolerable. Very effective non medicine pain relief – decreases use of analgesics – can be used as topical analgesics – can be used with other medication • • No contraindications, no risk of frost bites. Is suitable and safe to use for children, pregnancy and during breast feeding. Also very useful for elderly people.

Menthol - the most important ingredient of Ice Power cold gel • Menthol is one of the main active ingredients in Ice Power cold gel Makes the cooling sensation and decreases skin temperature approx. 5 -7 celcius. Menthol effecs on pain signals which makes the pain sensation more tolerable. Cold and menthol sensitive receptor TRPM 8 which belongs to the group of thermoregulation receptors inhibits the pain sensation Affect also to deeper tissues • TRPM 8 receptor activates in 28 -25 C • •

Ice Power cold gel provides a safe and long lasting cooling effect Ice Power cold gel Traditional cold products eg ice, cold packs

Proven efficacy of Ice Power Three different studies made with Ice Power

Ice Power cold gel cooling effect Study 1: Ice Power cold effect - proven effectiveness • Study published in The 6 th World Congress Miami World institute of pain • The effect of Ice Power cold gel was verified by both thermal skin sensors and simultaneous dynamic thermography • 6 healthy adults, Ice Power cold gel was applied 12 x 6 cm area • Maximal effect after 10 -15 min after application • Cooling effect was varying between 60 -90 minutes After 1 min After 10 min After 20 min

Ice Power cold gel - comparison of cold gels • Study 2: Comparison of cold gels There are big differences in cooling effect between different Cold gel brands in market • Short term cooling effect is a very common feature among cold gels • Unique formulation of Ice Power cold gel makes cooling effect longer • Study comparing Ice Power cold gel and cold gel ”X” • Effect measured with thermal camera • 2 ml of both cold gels was spread to upper part of the arm • Difference between two producs is very clear More on next page ->

Ice Power cold gel Study 2: Comparison of cold gels - there is a difference in cold gels Ice Power Cold gel • Cold gel ”X” Picture 1 Picture 3 • Pictures 1 -2: The first cooling effect was achieved with ethanol, which evaporates quickly from the skin – no long term cooling effect. Pictures 3 -4: Cooling effect of Ice Power lasts longer because optimal amount of menthol and formulation Ice Power cold gel. • • Picture 2 Picture 4 Provides long term cold effect. Also effects through thermoregulation receptors (CMR 1) -> affect to the pain also to deeper tissues.

Study 3: Ice Power effect in soft tissue injuries Ice Power cold gel – proven effect in soft tissue injuries Efficacy of Cold Gel for Soft Tissue Injuries, A Prospective Randomized Double -Blinded Trial Olavi V. Airaksinen, MD, Ph. D, Nils Kyrklund, MD, Kyösti Latvala, MD, Jukka P. Kouri, MD, Mats Grönblad, MD, Ph. D, and Pertti Kolari, Ph. D From the Departments of Physical and Rehabilitation Medicine, Kuopio University Hospital, Kuopio, Tampere University Hospital, Tampere, and Helsinki University Hospital and the Invalid Foundation, Helsinki, Finland Background: The use of cold treatment to limit edema, decrease pain, and induce effective muscle relaxation in soft tissue injuries is widespread. Purpose: To compare the efficacy of a cold gel with that of a placebo gel in patients with a soft tissue injury. Methods: Seventy-four patients with sports-related soft tissue injury were randomly assigned to active cold gel (Ice Power) or placebo gel groups. The gel was applied four times daily on the skin for 14 days. Clinical assessment was made after 7, 14 and 28 days with use of visual analog scale ratings. Published: THE AMERICAN JOURNAL OF SPORTS MEDICINE, Vol. 31, No. 5, 2003

Study 3: Ice Power effect in soft tissue injuries Ice Power cold gel – proven effect in soft tissue injuries Results: • • Pain scores decreased from 59 to 30 during the first week, to 14 by the second, and to 7 by the end of study in the cold gel group. In the placebo group, pain scores decreased from 58 to 45, 26, and 13, respectively (significant difference). Patient satisfaction with treatment was 71 in the cold gel group and 44 in the placebo group (significant difference). Disability decreased significantly more rapidly in the cold gel group.

Study 3: Ice Power effect in soft tissue injuries Ice Power cold gel – proven effect in soft tissue injuries According the study Ice Power cold gel was more effective than placebo in four weeks treatment. Statistical significance between the groups weeks 1, 2, 4 (p<0, 001). Conclusions: Cold gel therapy provided an effective and safe treatment for sports-related soft tissue injuries.

How to use Ice Power

When to use Ice Power cold gel - many different possibilities • • Muscle pain and tensions, stress pain Joint pain, rheumatic pain Back, shoulder and neck pain Recovery after exertion Reduce swelling In acute injuries use cold Bruises, haemorrhage packs for first aid, then Children’s growing pains continue cold treatment with Ice Power cold gel

How to use Ice Power cold gel · Apply Ice Power onto the skin and let it absorb. Don’t massage! · At first repeat after three hours, later on every six hours. · Can be used as course of treatment from a few days to 30 days depending on the degree of the muscle/soft tissue/joint pain or injury. · Ice Power is not harmful to health even in continuous use. · Non allergenic. Can be used by children and during pregnancy.

Summary • Cold therapy is one of the oldest way to manage pain! • Ice Power cold gel is an unique formulation providing fast and effective pain relief. • Ice Power cold gel is safe to use having more than 20 years of experience. • Scientifically proven efficacy.

Ice Power products

Ice Power - different possibilities For muscle pain For sports For joint pain

Ice Power Cold Gel • • • Effects immediately, short absorption time – A safe choice for whole family; also for children and during pregnancy and breast feeding. Significantly better results of long-acting care without contraindications Lowers skin temperature quickly by 5 -7 degrees, repercussions also on the deeper tissues. – Cold effect from natural ingredients: menthol and eucalyptus oil Usage 3 -4 per day or when necessary. Long term use allowed Clinically proven effect Packing sizes: 20 ml, 75 ml, 150 ml and 400 ml

Ice Power Roll • Easy and quick to use no matter where — to ensure continues treatment • Handy to use – without stained hands • Ideal to use on work or on trip • Packing size: 75 ml

Use of Ice Power Cold Gel • • Neck and shoulder problems Low back pain Post-operative care Rheumatic pain Arthrosis Contractures Muscle pain Low back pain with pregnancy • • • Stress injury Growth pains Bruises Sprains Strains Rupture

Ice Power Plus • • • Ice Power cold gel with MSM helps to strengthen the effect of cold gel For long term pain, pain with inflammation Not recommended for children and during pregnancy Package sizes: 100 ml, 200 ml

Ice Power Active • Cold gel with warming effect – First cooling effect relieves pain and afterwards warming effect releases muscle tensions -> dual effect • Warming effect increases blood circulation • Releases muscle tensions and promotes muscle recovery after physical exertion

Ice Power Cold Creme • Unique creme with Ice Power cooling effect • Skin friendly, massage Ice Power Creme in to the skin. • Easy to use everywhere, doesn’t stain • Suitable for older people, children and people with dry skin

Ice Power Cooling Patches • Fast and effective, cooling effect lasts up to 6 hours • Self-adhesive patch, pleasant to use • Enables long-term use e. g. in neck and shoulder pain and in back muscular tension • Cooling effect from menthol • Packing size: 5 patches/box

Ice Power Kids • • • Spreads easily and doesn’t stain. Quick absorption Suitable for children’s sensitive skin Fresh peppermint aroma Recommended over 2 years children

Use of Ice Power Kids • Children’s growing pains • Relax tired muscles after physical exercise and over exertion • Bumps and bruises • Speed up the healing of bruises • Minor sprains, strains • Cools the skin after minor accidents • Eases the discomfort caused by insect bites

Ice Power Magnesium cream • • For increased need of magnesium Relieves muscle cramps and muscle tension Contains magnesium in a well-absorbing sulphate form and menthol which gives a light cooling effect Light emulsion cream – does not stain Absorbs well and quickly No side effects (e. g. stomach irritation or diarrhea) Can be used also together with magnesium food supplements to make sure the right magnesium level is reached (e. g. in malabsorption)

Ice Power Magnesium cream • • • Magnesium absorbs well from the skin Study comparing magnesium taken orally vs absorption from the skin measuring the level of magnesium in blood circulation The study shows that by dosing Ice Power Magnesium Cream regularly during one week on the skin, the similar magnesium levels could be reached as with the singular dose magnesium citrate food supplement.

Ice Power Hot Warm Gel Use: • Problems with peripherial circulation • Non-inflammatory muscle tensions • Prevent injuries • Warm up muscles before exercise in cold Cautions: • Effect begins approxim. 1 hour after application • Sweating, sauna, warm shower, sun etc. increases effect • Packing sizes: 75 ml

Ice Power Sport Spray Long-lasting cold gel spray • Effect after few minutes, lasting up to 2 hours For acute injuries • Sport and stress injuries, knocks of children, strains and sprains Quick and easy to use • Easy dosing with spray • No dirty hands Effective and Safe • No risk for frost bite

Ice Power Sport Spray use with elastic compression

Ice Power for First Aid Ice Power Instant Cold Pack • Easy to use when you need • Can be used everywhere • One time use Ice Power Cold Spray • Short time effect • First Aid only

Ice Power Cold / Hot Pack · Can be cooled for relieving pain, inflammation and swelling. · Traditional form of cold therapy. · Cooling in refrigerator or freezer depending on use. · Can be used as warm therapy by warming it up in warm water-bath or in microwave. · Follow-up treatment with Ice Power cold gel

Ice Power Arthro Creme • Unique cold cream for joints. • Helps to relieve inflammation and swelling in joints. Suitable especially for small joints eg. fingers. • The Ice Power cooling effect is strengthened by Glucosamine, Chondroitine and MSM which are essential for well-being of joints • Suitable to use for all kinds of joint problems • Packing: 60 g tube

How to use Arthro Creme • Rub on the joint area with problems 2 -3 times a day • Recommended to use regularly (at least one month) • Ice Power Arthro Creme can also be used to strengthen the effect of e. g. joint pain medication. • According to the studies Ice Power Arthro Creme relieves significantly the mild and moderate joint pain and increases the mobility of joints.