Maryland Overdose Response Program Educational Training Program CORE

Maryland Overdose Response Program Educational Training Program CORE CURRICULUM CONDENSED May 31, 2017 Behavioral Health Administration Department of Health & Mental Hygiene dhmh. naloxone@maryland. gov

Program Overview A. Defining opioid, naloxone, and overdose B. Identifying an overdose C. How to respond D. Good Samaritan Laws E. How to obtain naloxone 6/8/2017

What is an Opioid? • Any drugs that contain • Prescription: opium or its derivative – Oxycodone • Natural or synthetic – Hydrocodone • Prescription medications – Oxymorphone or illegal drugs – Morphine • Pill, capsule, powder or – Codeine liquid • Heroin • Swallowed/drunk, • Fentanyl smoked, snorted or injected 6/8/2017

What is Naloxone? • • Reverses opioid overdose and restores breathing No potential for abuse or getting high No effect on someone who hasn’t taken opioids Side effects are minimal and rare Safe for children and pregnant women Intramuscular, intranasal or intravenous Wears off in 30 - 90 minutes Naloxone is only effective in reversing opioid overdoses 6/8/2017

What Is an Opioid Overdose? • Opioid overdose happens when a toxic amount of an opioid—alone or mixed with other opioid(s), drugs and/or substances— overwhelms the body’s ability to handle it. • Many opioid-related overdoses result from mixing prescription painkillers or heroin with benzodiazepines (benzos), cocaine and/or alcohol. 6/8/2017

Recognizing the Signs & Symptoms of an Opioid Overdose § § § § 6/8/2017 Loud snoring or gurgling noises Body very limp Unresponsive Skin pale/gray, clammy Lips/fingertips turn blue(ish) Pulse slow or erratic Breathing very slow, shallow, or not at all Unconscious

Responding to an Opioid Overdose 1. Rouse and Stimulate 2. Call 9 -1 -1 3. Give Naloxone 4. Further Resuscitation 5. Care for the Person 6/8/2017

Step 1: Rouse & Stimulate Noise: Shake person’s shoulders and yell: “[Name!] Are you all right? Wake up!” Pain: If no answer, do a sternal rub: rub Make a fist, rub your knuckles firmly up and down the breast bone. 6/8/2017

Sternal (Sternum) Rub 6/8/2017

Step 2: Call 9 -1 -1: Why? Get emergency medical help for someone experiencing an overdose! 1. May have complications or other health problems. 2. Naloxone is only temporary. 3. May need to give additional doses of naloxone. 4. May be a non-opioid overdose situation. 6/8/2017

3. Give Naloxone Step 3: Give Naloxone 6/8/2017

Intranasal Naloxone Amphastar: Narcan: 6/8/2017

Administering Amphastar Nasal Naloxone – Step by Step 1: Remove caps from 1: needle-less syringe. Step 2: Screw nasal atomizer 2: into top of syringe. Step 3: Remove cap from 3: prefilled vial of naloxone. Step 3: Gently twist naloxone vial into delivery device until you feel it “catch. ” 6/8/2017 Naloxone vial Atomizer 1 mg/1 m. L Needle-less syringe (delivery device)

Administering Amphastar Nasal Naloxone – Step by Step 5: Tilt back the head so the naloxone will not run out of the person’s nose. Step 6: Spray one-half (1 cc) of the naloxone up each nostril. 6/8/2017

Administering Amphastar Nasal Naloxone – Step by Step 7: Allow 1 -3 minutes for the naloxone to work. Continue resuscitation as necessary. Step 8: If breathing is not restored after 2 -3 minutes, 8: give another dose of naloxone (see Steps 5 & 6). of 6 Continue resuscitation as necessary. Step 9: Stay with the person and provide care as 9: directed until medical help arrives. 6/8/2017

Administering Narcan – Step by Step 1: Remove NARCAN Nasal Spray from the box. Peel back the tab with the circle to open the NARCAN Nasal Spray Step 2: Hold the NARCAN nasal spray with your thumb on the bottom of the plunger and your first and middle fingers on either side of the nozzle. 6/8/2017

Administering Narcan – Step by Step 3: Gently insert the tip of the nozzle into either nostril. Tilt the person’s head back and provide support under the neck with your hand. Gently insert the tip of the nozzle into one nostril, until your fingers on either side of the nozzle are against the bottom of the person’s nose. Step 4: Press the plunger firmly to give 4: the dose of NARCAN Nasal Spray. Remove the NARCAN Nasal Spray from the nostril after giving the dose. 6/8/2017

Administering Narcan – Step by Step 5: Allow 1 -3 minutes for the naloxone to work. Continue resuscitation as necessary. Step 6: If breathing is not restored after 2 -3 minutes, 6: give another dose of naloxone. Continue of resuscitation as necessary. Step 7: Stay with the person and provide care as 7: directed until medical help arrives. Note individual Narcan cannot be reused. 6/8/2017

Intramuscular/Injectable Naloxone 6/8/2017

Administering Injectable Naloxone – Step by Step: Step 1: Pop off the flip-top from naloxone vial. Step 2: Insert needle into vial and draw up 1 cc of naloxone into syringe. Step 3: Use alcohol wipe to clean injection site – shoulder, thigh or buttocks. Step 4: Inject needle straight into muscle (through clothes, if necessary), then push in plunger. . 4 mg/1 m. L Do not inject naloxone into the person’s heart, chest or back! 6/8/2017

Naloxone Injection Sites Needle can go through clothing Shoulder 6/8/2017 Thigh Buttocks (upper, outer quadrant)

Administering Injectable Naloxone – Step by Step 5: Allow 1 -3 minutes for the naloxone to work. Continue resuscitation as necessary. Step 6: If breathing is not restored after 2 -3 minutes, 6: give another dose of naloxone (see Steps 1 - 4). 4 Continue resuscitation as necessary. Step 7: Stay with person and provide care as directed 7: until medical help arrives. 6/8/2017 Maryland ORP Core Curriculum

Administering Evzio – Step by Step 6/8/2017

Administering Evzio – Step by Step 1: Pull off the red safety guard. – Note: The red safety guard is made to fit tightly. Pull firmly to remove. 6/8/2017

Administering Evzio – Step by Step Give Evzio Step 2: Place the Black end of EVZIO against the outer thigh, through clothing, if needed. Press firmly and hold in place for 5 seconds. EVZIO makes a distinct sound (click and hiss) when it is pressed against the thigh. This is normal and means that EVZIO is working correctly. Keep EVZIO firmly pressed on the thigh for 5 seconds after you hear the click and hiss sound. The needle will inject and then retract back up into the EVZIO autoinjector and is not visible after use. 6/8/2017

Administering Evzio – Step by Step Give Evzio Step 3: Allow 1 -3 minutes for the naloxone to work. Continue resuscitation as necessary. Step 4: If breathing is not restored after 2 -3 minutes, 4: give another dose of naloxone. Continue resuscitation as necessary. Step 5: Stay with person and provide care as directed 5: until medical help arrives. Note individual Evzio cannot be reused. 6/8/2017

Step 4: Further Resuscitation Assess breathing: if the person is not breathing, or if breath is shallow or short, Give rescue breaths. OR If you are trained in cardiopulmonary resuscitation (CPR), administer traditional CPR, chest compressions with rescue breaths. OR Follow the 9 -1 -1 dispatcher’s instructions. Continue until the person wakes up or medical help arrives. 6/8/2017

Assess Breathing Look, Listen & Feel If shallow or short breaths, or not breathing → start rescue breathing right away 6/8/2017

Rescue Breathing – Step by Step 1: Lay the person 1: on his/her back on a flat surface. Step 2: Tilt the chin to 2: open the airway. Step 3: Remove 3: anything blocking the airway. 6/8/2017

Rescue Breathing – Step by Step 4: Pinch the person’s nose closed completely. Step 5: Cover his/her mouth with your mouth and blow 2 regular breaths about 1 second each. Step 6: Breathe again. Give 1 breath every 5 seconds 6/8/2017

Step 5: Care for the Person • Stay with the person until medical help arrives • The person may feel sick, agitated or even vomit. • If s/he is unable to sit up, or if you have to leave for any period of time, put person in recovery position • Keep person calm and encourage him/her not to calm take more opioids. • If overdose re-occurs, give another dose of naloxone 6/8/2017

Recovery Position Face & body turned to side Hand supports head Bent knee supports body 6/8/2017

If You Administer Naloxone. . . Call the Poison Center 1 -800 -222 -1222 Within 1 -2 hours Or contact the entity that provided training. 6/8/2017

Good Samaritan Laws CODE OF MARYLAND, CRIMINAL PROCEDURE ARTICLE, § 1– 210 Code of Maryland, Health General § 13– 3110 A person who seeks, provides or assists with medical assistance for another person experiencing an alcohol- or drug-related medical emergency cannot be arrested, charged, or prosecuted for: • Possession of a controlled dangerous substance • Possession or use of drug paraphernalia • Providing alcohol to minors Calling 911 WILL NOT affect your PAROLE or PROBATION status An individual who administers naloxone to an individual believed to be experiencing and overdose shall have immunity from liability under §§ 6 -603 and 5 -629 of the Courts and Judicial Proceedings Article You cannot be held liable for a good faith attempt to help someone. 6/8/2017

Obtaining Naloxone q Any individual may receive a prescription for naloxone from any licensed health care provider with prescribing authority q You can obtain naloxone from an authorized ORP entity that dispenses naloxone q Any individual can obtain naloxone at a participating pharmacy through the statewide standing order. q As of June 1, 2017, there is no training or certificate requirement to obtain naloxone from a pharmacy under the statewide standing order. q For a list of pharmacies that stock naloxone visit bha. dhmh. maryland. gov/naloxone. 6/8/2017

[Opt. ] Naloxone Storage & Disposal Storage: o Do not attach naloxone to delivery device until ready to use o Store naloxone in original package at room temperature; avoid exposure to light o Keep in a safe place away from children & pets, but easy to access in case of emergency Expiration: o Naloxone loses its effectiveness over time o Check expiration date on label Disposal: o Check with a local health department or pharmacy about properly disposing of expired naloxone 6/8/2017

[Opt. ] How NOT To Respond to an Opioid Overdose Anecdotal Remedy Use ice to cool down body Possible Consequence(s) → Slowed heart rate, arrhythmia Put person in bath/shower → Drowning Hit/slap or burn fingers/feet → Bruising, broken bones, infection, amputation Give drink/induce vomiting → Choking to death Inject person with cocaine, → High blood pressure, infection salt water, milk, epinephrine 6/8/2017

[Opt. ] Opioid Overdose Prevention Tips v Keep all medicine in a safe place, such as a locked cabinet. (Naloxone should be kept readily available. ) v Properly dispose of expired or unwanted medications. v Take only medicine prescribed for you and only as directed. v Never share your prescription drugs with anyone else. v If you have breathing problems (e. g. asthma, sleep apnea), check with your doctor before taking opioids. v Never mix pain medication with alcohol, benzos, sleeping pills, muscle relaxants, anti-nausea drugs, other opioids or illegal drugs. 6/8/2017

[Opt. ] Opioid Overdose Prevention Tips v Do not use alone. v Make an overdose prevention plan and share it with someone you trust to give you naloxone if needed. v If you have not used opioids in a while, your tolerance will be lower and risk for overdose greater, so use less opioids than you normally would. v You are also at greater risk for overdose if you have overdosed before. v Always keep naloxone on hand. v Get treatment for drug dependence or addiction. v Seek professional help if you are depressed. v Call a crisis hotline [insert #] or 9 -1 -1 if you are suicidal. 6/8/2017

Maryland Overdose Response Program Core Curriculum Health-General Article, Title 13, Subtitle 31, Annotated Code of Maryland Sections 13 -3101 – 3109 Code of Maryland Regulations, Title 10, Subtitle 47, Chapter 08, Regulations. 01 -. 11 6/8/2017