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What is Prunes ？ • Also known as dried plum, mainly produced in California and France • Plums dehydrated in hot temperature (85 -90℃) for 18 hours continuous, after which they are called prunes. Prunes are further minced, filtered, and processed to produce prunes concentrate juice or prune sauce • A Comprehensive food: high in antioxidant, high fibre -relieves constipation, reduce damage from free radical oxidation. • Convenient for busy lifestyle, easy to carry and high in nutritional value • One of the secret weapon for longevity & Constipation

Of Caucasians Longevity Secrets Ø Ø Optimistic attitude towards life Warm and happy family Hospitable habits Highly developed medicines 2000 years ago, already know prunes rich in nutrients

Do you know ？ There are lots of European plum trees growing tall and healthy on the mountains in the Caucasus region between the Black Sea and the Caspian Sea. Plum trees blossom in the spring with white flowers, and in summer they bear sweet purple fruits. It is believed that plums are fruits of immortality. Coincidentally, those who eat them do enjoy longevity indeed.

Minerals High in antioxidants （Calcium、Iron、 Potassium、 Boron） ORAC Vitamins （A/B complex/C） Fiber Cholesterol and Fat free Folate Click for more information!

THE PERFECT MATCH Well 3 Prune Berries • 36, 600 ORAC unit of antioxidants, high dietary fibre • • With 6 types of mixed berries (Red grape/white grape/yumberry/ blueberry/raspberry/ mulberry) Produced by GMP factory with advanced technology • • Natural prunes from free-pollution farm in California, Japan technology No added colouring/sugar/additives/ preservatives

Natural Prunes from free pollution plantation in California

Mixed berries concentrate juice (red grape / white grape / blueberry / yumberry / raspberry / mulberry)

Concentrated berry juice Red Grape White Grape Function High resveratrol*, polyphenols have strong antioxidant and antiinflammatory properties. Regulate blood pressure, improve cardiac function, prevent atherosclerosis and stroke, anti-allergic, promote lung health and beauty. * their roots have properties that can help fight cardiovascular diseases Blueberry Improves eyesight and cardiovascular function. Balances blood sugar, improves brain function and memory. Bayberry Rich in vitamin C and organic acid and helps digestion, increases immunity and improves skin texture. Raspberry Antibacterial. Rich in vitamin C, high in antioxidants and low glycemic index, suitable for diabetics. Mulberry High in iron. Improves blood circulation, anti-inflammatory, protects eyes, good for hair darkening and beauty

Superfruit 1. High antioxidant 2. High nutritional value 3. Promotes gastrointestinal motility

Function Prunes Nutrients Antioxidants Vitamin A Vitamin C • • High antioxidant-8, 059µmol TE/100 g Anti-aging, slow s brain aging Protects cells, eliminates free radicals and prevents cancer Chlorogenic acid and proanthocyanidins contain high antioxidant index • • Protects eyesight Maintenance of epithelial cell function; for glowing, soft and delicate skin, wrinkle prevention effect Maintenance of hair Helps bone and tooth growth • • Promotes bone growth, muscle development 2. egg yolks Prevent s hardening of the arteries, protects teeth and helps iron absorption Top Ten Foods rich in Iron: 1. Dried fruit (prunes, raisins) Potassium • • • 3. Dark/ green leafy vegetables (spinach, kale) Prevents heart disease and stroke. (particularly important for the elderly with low folate level) 4. red meat Prevention of megaloblastic anemia and leukopenia 5. cereals and grains Pregnant women often take folate to prevent underweight baby, premature 6. oysters, clams, scallops birth, infant with cleft palate (cleft lip) and other congenital malformations 7. turkey or chicken offal 8. Beans Maintains muscle elasticity Maintains body electrolyte balance 9. liver Helps nerve impulses as well as energy release from metabolic process 10. Artichoke Iron • • • Prunes are rich in iron; ranked top ten and has 11 times more than apples Source: Facial lustre, glow, and can increase physical strength Iron is crucial for pregnant women, lactating women and infants Jadual Boron • Helps in the absorption of calcium to prevent osteoporosis Dietary fiber • • Promote gastrointestinal motility, intestinal cleansing Commonly known as "constipation inhibitor“ • Folate • •

High Antioxidant

Free radicals are normally caused by aging and external factors, such as smoking, pollutions and sun exposure. We are fine as long as there’s enough antioxidants in our body. Otherwise, free radicals will attack, and ultimately destroy healthy body cells, causing damage and leading to life-threatening diseases such as: - Immune dysfunction Cancer Cardiovascular diseases Cognitive impairment Deterioration of eyesight Dementia or Alzheimer's disease Sagging skin, systemic aging

Comparison of ORAC value in selected fruits • USDA recommends a daily intake of at least 3000 ORAC units to maintain metabolic balance. Source : US Department of Agriculture Malaysian Dietary Guideline

What is ORAC? It’s an acronym for Oxygen Radical Absorption Capacity the HIGHER the ORAC value， the STRONGER the antioxidant’s capacity to inhibit free radicals. F irst Inventioni First developed in 1992 by Dr Guo Hua Cao from U. S. National Institute of gerontology and assisted by Dr. Ronald L. Prior. Source: http: //www. brunswicklabs. com. cn/

Antioxidant Index 31 times OR 14 times OR 9 times 1 sticks of Well 3 Prune Berries (10 g) OR 3 times

Anthocyanins and phenolic acids are the phytochemicals contained in prunes. Neochlorogenic acid and chlorogenic acid are phenolic acids found in abundance to help inhibit oxidation of low-density lipoprotein (LDL) , and Reduce Heart Disease Morbidity rate.

Research reports

Prunes antioxidant function (Mg/day) 2. 5 CREATOL 8 -isoprostane (Oxidative stress markers) (Pg/day) 360 340 2 320 1. 5 300 1 280 0. 5 260 0 240 Before After 4 weeks after stopping eating

Prunes antioxidant function Cancer Rat(%) 70 60 Normal daily diet 50 40 30 20 10 0 Normal daily diet + chlorogenic acid Source: Shimizu M, et al : J Toxicol Sci. 1999 Dec; 24(5): 433 -9

Prunes antioxidant function number of cells(%) Colorectal Cancer Gastric Cancer 120 100 * 80 80 ** 60 40 40 20 20 0 0. 1 0. 3 0 Prune Extract(mg/ml) *p<0. 05 **p<0. 01 vs. control ** 0. 0 0. 1 0. 3

Prunes antioxidant function 180 Normal cell Number of cells(%) 160 140 120 100 80 60 40 20 0 0. 1 0. 3 Prune Extract(mg/ml) *p<0. 05 **p<0. 01 vs. control

Constipation Inhibitor

Prunes with mixed berries are high-fibre food, it supplies essential soluble and insoluble fibres to our body. Soluble fibre (pectin) Insoluble fibre Reduces blood Laxative – soothes cholesterol level and bowel blood glucose level Sorbitol combines with water, to soften stool and promote healthy bowel movements According to the American Institute for Cancer Research, eating a high-fiber diet can reduce the risk of bowel cancer.

* Constipation inhibitor Published in the 44 th Fukuoka, Annual Meeting of Japanese Society of Clinical Nutrition • • Prune juice Water (320 g/day) (160 g/day) Frequency/ day 0. 9± 0. 2 1. 1± 0. 7 0. 6± 0. 2 0. 5± 0. 2 Faecal form 2. 4± 0. 6 2. 2± 1. 0 1. 7± 0. 7 1. 2± 0. 6 Faecal softness 2. 4± 0. 6 1. 1± 0. 7 1. 6± 0. 7 0. 5± 0. 2 One prune contains 0. 7 grams of dietary fibre (about 7%), and four times more than an apple Prunes contain natural loose stool laxative ingredient-Dihydrophenylisatin, to assist muscle contraction, soften stool & ease excretion *A healthy Malaysian (> 2 years) daily intake is 20 -30 grams of fibre. Adult male: 38 g / day; adult female: 25 g /day

Dietary Fiber Source: Malaysian Foods Composition Database, Nutrition Society of Malaysia 2 Banana OR 3 Slices papaya OR 3 Apples OR Half a pumpkin 2 Stick Well 3 Prune Berries OR 170 g vegetables OR 4 Tomatoes

Other functions - Reduce cholesterol - Prevent hypertension/stroke - Prevent osteoporosis - Help bone metabolism - Inhibit bacterial growth - Improve beauty

Reduce Cholesterol

Constipation Savior Reduce cholesterol American Journal of Clinical Nutrition • Prunes have cholesterol-reducing effect • Bad cholesterol* in blood and bile acids in faeces are obviously reduced, and 20% increament in stool volume** * LDL, low-density-lipoprotein cholesterol ** Subjects consecutively took 12 prunes daily for eight weeks

Prevent hypertension/stroke

Prevent hypertension/stroke Amount of Potassium in Foods (mg) Broccoli(40 g) Orange(100 g ) Kiwi(60 g) Green Pea(50 g) pomelo(200 g ) Fermented soy(50 g) Spinach(70 g ) Banana(120 g ) Sweet potato(100 g) Concentrated Prune Essence(55 g) Potassium is a very important substance to maintain normal activities in body cells, tissue and organs. It is responsible for the transportation of nutrients into cells and waste out of cells, helps muscle contraction, reduces the risk of recurrent kidney stones, reduces high blood pressure or stroke risk and prevents bone loss caused by agieng.

Ratio of potassium and sodium in urine P < 0. 05 Before P < 0. 05 After 4 weeks after stop eating U. S. FDA says that eating foods low in sodium and potassium (at per serving at least 350 milligrams of potassium and less than 140 mg of sodium) such as prunes can reduce the risk of high blood pressure and stroke.

Prevent Osteoporosis

Prevent Osteoporosis Prunes contain a variety of natural compounds eg. organic acids, calcium, magnesium, phosphorus, vitamin K, copper, boron and can also maintain bone health. Calcium, magnesium, phosphorus Essential element to strengthen bones Organic acids Enhance calcium absorption Copper Facilitates bone formation Vitamin K Increases bone density and reduces the incidence of fractures Boron Regulates mineral metabolism, optimises hormone level and control the loss of calcium during urination Source: Critical Reviews in Food Science and Nutrition 41(4), 251(2001)

Prevent Osteoporosis Subject: postmenopausal women consecutively consume sufficient calcium and vitamin D for 90 days, while taking 8 -10 prunes with water, with the following results: • Prunes is more effective than hormone therapy and other drugs in reducing body's bone loss • Effectively rebuild bone osteoporosis Dr. BAHRAM H. ARJMANDI • Chairman of the Department of Nutrition, Food and Exercise Sciences, Florida State University • World’s expert in bone health • Scientific evidence showed that anti-bone loss mechanism is related to the high antioxidant capacity Unprocessed fresh plums do not have such effects

Inhibit Pathogenic growth

Inhibit pathogenic growth 8 The 3 rd Congres of Japanese Society of Nutrition and Food Science. (2003) Didn’t consume prune 7. 5 Consumed prune 7 6. 5 6 5. 5 5 4 6: 00 7: 00 8: 00 9: 00 10: 00 11: 00 12: 00 Quinic acid can acidify urine so that pathogenic cannot grow, and resists pathogenic adhesion so that pathogenic cannot feed on the urethra, thus preventing urinary tract infection.

Amount of quinic acid in fruits(g/100 g) Plum Kiwi Bilberry Prune Concentrated prune essence Source: ITE Letters on Batteries, New Technologies & Medicine, 4, 639 (2003) 4. 28

Improve beauty - Antioxidants can slow or prevent the skin cells from damage caused by free radicals. - Vitamins such as A and C, can help protect the skin from sun damage, thus preventing ageing, dull skin and wrinkles. - Prune is rich in natural compounds that can promote growth of skin cells, help the skin healing process. - Promote healthy bowel movement, reduce constipation, develop a non-toxic body , with an inner glow of healthy skin.

FAQ

Q&A 1. Is Well 3 Prune Berries a medicine/drug? No, Well 3 Prune Berries is a natural supplement, it does not contain any chemical substances. It can replenish our body's nutrients and minerals, along with ANT concept of cleanse, restore, build, protect. 2. Well 3 Prune Berries is suitable for: • Children – supply complete nutrients, promote healthy • Alcoholics – Helps in breaking down alcohol and reducing the effect of copper in body. growth • High blood pressure patients – Prunes with high potassium, low sodium, is very suitable for • Pregnant women – Enhance essential nutrients for mothers during pregnancy and after delivery. • Elderly – rich in calcium to help prevent osteoporosis • Anaemia patients – Helps in heme synthesis and prevents anaemia them • Constipation patients – High fibres can improve bowel movements, excretion, alleviate constipation and prevent haemorrhoids • Vegetarians – Best choice for vegetarians for source of iron. 3. Can pregnant women consume Well 3 Prune Berries? Pregnant women can take Well 3 Prune Berries safely. It contains iron, calcium, fibre and other nutrients which can help enhance foetal and mother’s health. Generally, pregnant women are accustomed to suffer from constipation, and Well 3 Prune Berries can help them to relieve constipation. 4. Is there any other method to consume Well 3 Prune Berries instead of taking it directly? You can use it as a spread, or natural seasoning in cooking baby food, ice cream, cake, etc.

Price list RP RM 108. 00 MP RM 90. 00 RP RM 504. 00 CV : 10 30 sachets x 10 g / box MP RM 420. 00 CV : 50 30 sachets x 10 g x 5 boxes Recommended intake of atleast two sticks per day. Can be directly consumed or with 100 ml water (room temperature). Of course, you may also add it into your meals.