Surveillance Epidemiology and Tracing Overview Adapted from the
- Slides: 29
Surveillance, Epidemiology, and Tracing Overview Adapted from the FAD PRe. P/NAHEMS Guidelines: Surveillance, Epidemiology, and Tracing (2014).
This Presentation • • Introduction to when and why Definitions for technical terms Organizational structure Overview of Surveillance Plan FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Surveillance, Epidemiology, and Tracing Activities FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Introduction • Foreign animal disease (FAD) – Terrestrial or aquatic disease or pest not known to exist in the United States • High pathogenicity avian influenza • Foot-and-mouth-disease – Preventive measures for introduction • Import restrictions • Exclusion activities at borders/ports of entry • Public education programs FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Introduction (cont’d) • FAD investigation – Initiated if an FAD is suspected • Foreign Animal Disease Diagnostician • Guidance Document 12001 • APHIS FAD PRe. P Manual 4 -0 • Once an FAD is confirmed – Surveillance, epidemiology, and tracing response components are activated • Provide real-time understanding • Enable decisions on interventions FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Purpose • Surveillance, epidemiology, and tracing techniques are used to: – Detect cases – Understand disease characteristics – Identify risk factors – Provide information for decision-making – Design and implement control measures – Evaluate the effectiveness of the control measures implemented FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Definitions • Surveillance – An intensive form of data recording that encompasses gathering, documenting, and analyzing data • Epidemiology – The study of the distribution of disease in populations and of factors that determine its occurrence • Tracing – Information gathering on recent movements of animals, personnel, vehicles, and fomites to identify potential spread of disease, and source FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Zone/Area Designations Summary of Zone and Area Designations Infected Zone (IZ) Buffer Zone (BZ) Zone that immediately surrounds an infected Premises Control Area (CA) Surveillance Zone (SZ) Vaccination Zone (VZ) Consists of an Infected Zone and Buffer Zone that immediately surrounds an Infected Zone or Contact Premises Zone outside and along the border of a Control Area Emergency Vaccination Zone is classified as either Containment Vaccination Zone (typically inside the control area) or Protection Vaccination Zone (typically outside Control Area). This may be a secondary zone designation FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Incident Command System • Incident Command System (ICS) – Flexible and scalable • Number and names of deployed groups will vary – Planning and Operations Sections – Incident Action Plan FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Surveillance and Epidemiology FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Role of Surveillance • During an FAD outbreak, surveillance plays a key role in: – Identifying the infectious agent – Determining the scope of the outbreak – Assessing the effectiveness of eradication and control efforts – Demonstrating a return to disease free status FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Surveillance Plan Elements • • Disease description Surveillance objectives Stakeholders and responsible parties Population description Case definitions Data sources Sampling methods Diagnostic tests FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Case Definitions • Suspect case – Animal showing clinical signs compatible with FAD • Presumptive positive case – Animal with clinical signs consistent with FAD and positive test results • Confirmed positive case – Agent has been isolated and identified using approved tests FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Data Sources • Livestock producers • Veterinarians • Livestock organizations • Disease reporting or notification systems • Control programs • Sentinel units FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview • Post mortem diagnostic specimen collection • Wildlife data USDA APHIS and CFSPH
Sampling Methods • Considerations for accurate and practical sampling methods: – Sample type – Sample size – Random sampling vs. targeted sampling – Sampling duration and frequency – Sample areas/locations – Availability of diagnostic tests – Pooled testing FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Types of Specimens • Blood or serum • Skin or vesicular lesions – Epithelial tissue or vesicular fluid • Feces, rectal swabs, cloacal swabs, or genital tract swabs • Nasal discharge, saliva, tears • Semen samples • Tissues – Tonsil, spleen, kidney, liver, lymph node, lung, brain, etc. • Milk • Nasal, or • Environmental oropharyngeal swabs samples FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Core Functions • Surveillance – Ongoing data collection, analysis, interpretation, and dissemination – Used to determine specific actions for FAD mitigation • Field investigation – Used to collect additional information about cases identified via surveillance • Disease source, history of disease, etc. FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Core Functions (cont’d) • Analytic studies – Utilizes information gleaned from surveillance activities and field investigations – Disease rates and risk factors • Evaluation – Effectiveness – Efficacy – Impact of activities FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Disease Occurrence • Endemic – Present in a population or geographical area at times • Outbreak – Occurrence of more cases of disease than expected in a given area, or a specific group, over a particular time period • Pandemic – An outbreak/epidemic that has spread over several countries FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Risk Factors • A characteristic that is associated with an increase in the occurrence of a particular disease • May include: – Age – Species – Location – Contact FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Epidemiological Principles • Prevent contact between the FAD agent and susceptible animals – Quarantine, movement controls, biosecurity procedures, target depopulation • Stop production of FAD agent by infected or exposed animals – Slaughter or mass depopulation • Increase the disease resistance of susceptible animals to the FAD agent – Emergency vaccination FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Phases of Investigation • Generally, disease outbreaks are investigated in three phases: – Descriptive phase – Analytic phase – Intervention phase FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Tracing Animal Movements FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Tracing • Trace-back – Animals, animal products, fomites, people, vehicles, equipment, and possible vectors that have been moved onto an Infected Premises – Establish the origin of the agent/hazard FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Tracing (cont’d) • Trace-forward – Animals, animal products, fomites, people, vehicles, equipment, and possible vectors that have left the Infected Premises FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Additional Operational Procedures • A variety of strategies are required to contain, control and/or eradicate an FAD – Biosecurity – Health and safety – Personal protective equipment – Cleaning and disinfection – Quarantine and movement control FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
For More Information • FAD PRe. P/NAHEMS Guidelines: Surveillance, Epidemiology, and Tracing, and SOP: Surveillance – http: //www. aphis. usda. gov/fadprep • Surveillance, Epidemiology, and Tracing web-based training module – http: //naherc. sws. iastate. edu/ FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Guidelines Content Authors (CFSPH) • Kerry Leedom Larson, DVM, MPH, Ph. D, DACVPM • Glenda Dvorak, DVM, MPH, DACVPM • Janice Mogan, DVM • Courtney Blake, BA Reviewers (USDA APHIS VS) • • Dr. Dr. R. Alex Thompson Lowell Anderson Steve Goff Fred Bourgeois FAD PRe. P/NAHEMS Guidelines: Surveillance, Epi, and Tracing - Overview USDA APHIS and CFSPH
Acknowledgments Development of this presentation was by the Center for Food Security and Public Health at Iowa State University through funding from the USDA APHIS Veterinary Services PPT Authors: Patricia Futoma, Veterinary Student; Kerry Leedom Larson, DVM, MPH, Ph. D, DACVPM Reviewers: Janice Mogan, DVM, Melissa Lang, BS
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