Polycythemia Vera in a Dog Case 19 History

Polycythemia Vera in a Dog Case 19 전북대학교 수의학과 문보미

History taking ® Female ® 14 months old ® Old English sheepdog

Laboratory examination § Hemogram - PCV : 83% Hb : 29. 6 g/㎗ RBC count : 13. 78× 106/㎕ WBC : 9, 900/㎕ Thrombocyte : 94, 000/㎕ (modest thrombocytopenia) 정맥절개술(Phlebotomy) 실시

§ Blood gas values - PO 2 : 90. 0 mm. Hg - PCO 2 : 24. 5 mm. Hg - p. H : 7. 60 - CO 2 농도 : 19. 3 m. M/L - HCO 3 - : 18. 7 m. Eq/L

§ Blood volume - Evans blue와 51 Cr이용 - Plasma : 54. 0㎖/㎏ - RBC : 106. 0㎖/㎏ - TOTAL blood volume : 160. 0㎖/㎏ (정상치 : 80 -90㎖/㎏)

Erythrocyte fragility test : normal - 0. 33% buffered Na. Cl 용액에서 - 0. 55% 용혈로 시작 완전용혈 § Erythrocyte kinetics - 51 Cr 반감기(T 1/2) = 56일 - 59 Fe 운반속도(transfer rate) = 8. 88 ㎎/100㎖/day §

March 23 March 30 April 9 April 17 April 24 RBC(× 106/㎕) 13. 78 12. 94 13. 92 7. 30 7. 07 Hemoglobin(g/㎗) 29. 6 28. 0 27. 6 14. 5 14. 8 PCV(%) 83. 0 80. 0 43. 0 45. 0 MCV(f. L) 60. 2 61. 8 57. 5 58. 9 63. 6 MCHC(%) 35. 6 35. 0 34. 5 33. 7 32. 9 MCH(pg) 21. 4 21. 6 19. 9 20. 9 Nucleated RBC/100 WBC 0 2 0 0 0 Reticulocytes(%) - 0. 8 - Anisocytosis slight slight Polychromasia slight slight Erythrocyte

March 23 March 30 % % Leukocytes WBC/㎕ 9, 900 8, 600 April 9 April 17 % 10, 300 April 24 % 9, 300 % 10, 300 0 0. 0 172 2. 0 0 0. 0 Neutrophils 5, 940 60. 0 5, 504 64. 0 5, 099 49. 5 5. 766 62. 0 5, 459 53. 0 Lymphocytes 2, 673 27. 0 2, 150 25. 0 4, 120 40. 0 2. 371 25. 5 3, 039 29. 5 Monocytes 693 7. 0 688 8. 0 618 6. 0 558 6. 0 463 4. 5 Eosinophils 594 6. 0 86 1. 0 463 4. 5 605 6. 5 1, 287 12. 5 0 0. 0 51 0. 5 Band neutrophils Basophils Plasma Total plasma proteins(g/㎗) 7. 0 6. 8 6. 7 4. 6 6. 7 Fibrinogen(g/㎗) 0. 2 0. 1 0. 3 Thrombocytes(/㎕) 94, 000 90, 000 - - 352, 000