Contagious ecthyma Contagious Ecthyma Overview Organism History Epidemiology
![Contagious ecthyma Contagious Ecthyma Contagious ecthyma Contagious Ecthyma](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-1.jpg)
![Overview Organism History Epidemiology Transmission Disease in Humans Disease in Animals Prevention and Control Overview Organism History Epidemiology Transmission Disease in Humans Disease in Animals Prevention and Control](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-2.jpg)
![The Organism The Organism](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-3.jpg)
![The Organism Orf virus Genus Parapoxvirus Family Poxviridae Viability One month on wool/hides after The Organism Orf virus Genus Parapoxvirus Family Poxviridae Viability One month on wool/hides after](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-4.jpg)
![History History](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-5.jpg)
![History Orf described in animals Sheep: 1787 Goats: 1879 Orf described in humans 1923 History Orf described in animals Sheep: 1787 Goats: 1879 Orf described in humans 1923](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-6.jpg)
![Epidemiology Epidemiology](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-7.jpg)
![Geographic Distribution Found worldwide in sheep-raising countries United States Western states most affected Orf Geographic Distribution Found worldwide in sheep-raising countries United States Western states most affected Orf](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-8.jpg)
![Who Is At Risk? Close contact with sheep/goats Herders Sheep-shearers Veterinarians Butchers Abattoir workers Who Is At Risk? Close contact with sheep/goats Herders Sheep-shearers Veterinarians Butchers Abattoir workers](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-9.jpg)
![Transmission Transmission](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-10.jpg)
![Transmission Virus found in skin lesions/scabs Enters skin through cuts, abrasions Direct contact Fomites Transmission Virus found in skin lesions/scabs Enters skin through cuts, abrasions Direct contact Fomites](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-11.jpg)
![Disease in Humans Disease in Humans](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-12.jpg)
![Clinical Signs Usually single skin lesion Small, firm papule Fingers or hands Eventually lesion Clinical Signs Usually single skin lesion Small, firm papule Fingers or hands Eventually lesion](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-13.jpg)
![Diagnosis Electron microscopy Biopsy PCR Histopathology Virus isolation Serology, antigen detection Used in research Diagnosis Electron microscopy Biopsy PCR Histopathology Virus isolation Serology, antigen detection Used in research](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-14.jpg)
![Treatment Usually self-limiting Supportive care Wound dressings Local antiseptics Finger immobilization Antibiotics for secondary Treatment Usually self-limiting Supportive care Wound dressings Local antiseptics Finger immobilization Antibiotics for secondary](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-15.jpg)
![Disease in Animals Disease in Animals](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-16.jpg)
![Species Affected Sheep Goats Alpacas Camels Reindeer Musk oxen Bighorn sheep Deer Prong-horn antelope Species Affected Sheep Goats Alpacas Camels Reindeer Musk oxen Bighorn sheep Deer Prong-horn antelope](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-17.jpg)
![Clinical Signs Papules, pustules, vesicles Lips, nose, ears, eyelids, mouth Progress to thick, friable Clinical Signs Papules, pustules, vesicles Lips, nose, ears, eyelids, mouth Progress to thick, friable](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-18.jpg)
![Diagnosis Often diagnosed symptomatically Confirmation Electron microscopy (scabs) PCR Other tests (less common) Virus Diagnosis Often diagnosed symptomatically Confirmation Electron microscopy (scabs) PCR Other tests (less common) Virus](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-19.jpg)
![Treatment No specific treatment Intraoral lesions Diathermy Cryosurgery Insect repellents Antibiotics Secondary infections Supportive Treatment No specific treatment Intraoral lesions Diathermy Cryosurgery Insect repellents Antibiotics Secondary infections Supportive](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-20.jpg)
![Prevention and Control Prevention and Control](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-21.jpg)
![Prevention in Humans Avoid contact with infected animals, scabs/crusts, wool, and hides Especially if Prevention in Humans Avoid contact with infected animals, scabs/crusts, wool, and hides Especially if](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-22.jpg)
![Prevention in Animals Quarantine new animals Keep equipment/fomites clean Vaccination Live virus vaccine Only Prevention in Animals Quarantine new animals Keep equipment/fomites clean Vaccination Live virus vaccine Only](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-23.jpg)
- Slides: 23
![Contagious ecthyma Contagious Ecthyma Contagious ecthyma Contagious Ecthyma](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-1.jpg)
Contagious ecthyma Contagious Ecthyma
![Overview Organism History Epidemiology Transmission Disease in Humans Disease in Animals Prevention and Control Overview Organism History Epidemiology Transmission Disease in Humans Disease in Animals Prevention and Control](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-2.jpg)
Overview Organism History Epidemiology Transmission Disease in Humans Disease in Animals Prevention and Control
![The Organism The Organism](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-3.jpg)
The Organism
![The Organism Orf virus Genus Parapoxvirus Family Poxviridae Viability One month on woolhides after The Organism Orf virus Genus Parapoxvirus Family Poxviridae Viability One month on wool/hides after](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-4.jpg)
The Organism Orf virus Genus Parapoxvirus Family Poxviridae Viability One month on wool/hides after healed Up to 12 years in lesion crusts Resistant to inactivation lesions
![History History](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-5.jpg)
History
![History Orf described in animals Sheep 1787 Goats 1879 Orf described in humans 1923 History Orf described in animals Sheep: 1787 Goats: 1879 Orf described in humans 1923](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-6.jpg)
History Orf described in animals Sheep: 1787 Goats: 1879 Orf described in humans 1923
![Epidemiology Epidemiology](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-7.jpg)
Epidemiology
![Geographic Distribution Found worldwide in sheepraising countries United States Western states most affected Orf Geographic Distribution Found worldwide in sheep-raising countries United States Western states most affected Orf](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-8.jpg)
Geographic Distribution Found worldwide in sheep-raising countries United States Western states most affected Orf reported on 40% of U. S. sheep operations
![Who Is At Risk Close contact with sheepgoats Herders Sheepshearers Veterinarians Butchers Abattoir workers Who Is At Risk? Close contact with sheep/goats Herders Sheep-shearers Veterinarians Butchers Abattoir workers](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-9.jpg)
Who Is At Risk? Close contact with sheep/goats Herders Sheep-shearers Veterinarians Butchers Abattoir workers
![Transmission Transmission](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-10.jpg)
Transmission
![Transmission Virus found in skin lesionsscabs Enters skin through cuts abrasions Direct contact Fomites Transmission Virus found in skin lesions/scabs Enters skin through cuts, abrasions Direct contact Fomites](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-11.jpg)
Transmission Virus found in skin lesions/scabs Enters skin through cuts, abrasions Direct contact Fomites Healthy animals may be carriers Vaccines Contain live virus May infect humans
![Disease in Humans Disease in Humans](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-12.jpg)
Disease in Humans
![Clinical Signs Usually single skin lesion Small firm papule Fingers or hands Eventually lesion Clinical Signs Usually single skin lesion Small, firm papule Fingers or hands Eventually lesion](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-13.jpg)
Clinical Signs Usually single skin lesion Small, firm papule Fingers or hands Eventually lesion by crust covered Often resolves spontaneously Immunosuppressed people at greater risk for complications
![Diagnosis Electron microscopy Biopsy PCR Histopathology Virus isolation Serology antigen detection Used in research Diagnosis Electron microscopy Biopsy PCR Histopathology Virus isolation Serology, antigen detection Used in research](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-14.jpg)
Diagnosis Electron microscopy Biopsy PCR Histopathology Virus isolation Serology, antigen detection Used in research only
![Treatment Usually selflimiting Supportive care Wound dressings Local antiseptics Finger immobilization Antibiotics for secondary Treatment Usually self-limiting Supportive care Wound dressings Local antiseptics Finger immobilization Antibiotics for secondary](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-15.jpg)
Treatment Usually self-limiting Supportive care Wound dressings Local antiseptics Finger immobilization Antibiotics for secondary infections Surgery (large lesions) Cryotherapy
![Disease in Animals Disease in Animals](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-16.jpg)
Disease in Animals
![Species Affected Sheep Goats Alpacas Camels Reindeer Musk oxen Bighorn sheep Deer Pronghorn antelope Species Affected Sheep Goats Alpacas Camels Reindeer Musk oxen Bighorn sheep Deer Prong-horn antelope](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-17.jpg)
Species Affected Sheep Goats Alpacas Camels Reindeer Musk oxen Bighorn sheep Deer Prong-horn antelope Wapiti Dogs Ingestion of infected carcasses
![Clinical Signs Papules pustules vesicles Lips nose ears eyelids mouth Progress to thick friable Clinical Signs Papules, pustules, vesicles Lips, nose, ears, eyelids, mouth Progress to thick, friable](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-18.jpg)
Clinical Signs Papules, pustules, vesicles Lips, nose, ears, eyelids, mouth Progress to thick, friable scabs Lesions very painful Usually resolves weeks More severe in goats in 1 to 4 Boer
![Diagnosis Often diagnosed symptomatically Confirmation Electron microscopy scabs PCR Other tests less common Virus Diagnosis Often diagnosed symptomatically Confirmation Electron microscopy (scabs) PCR Other tests (less common) Virus](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-19.jpg)
Diagnosis Often diagnosed symptomatically Confirmation Electron microscopy (scabs) PCR Other tests (less common) Virus isolation Serology ELISA
![Treatment No specific treatment Intraoral lesions Diathermy Cryosurgery Insect repellents Antibiotics Secondary infections Supportive Treatment No specific treatment Intraoral lesions Diathermy Cryosurgery Insect repellents Antibiotics Secondary infections Supportive](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-20.jpg)
Treatment No specific treatment Intraoral lesions Diathermy Cryosurgery Insect repellents Antibiotics Secondary infections Supportive care
![Prevention and Control Prevention and Control](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-21.jpg)
Prevention and Control
![Prevention in Humans Avoid contact with infected animals scabscrusts wool and hides Especially if Prevention in Humans Avoid contact with infected animals, scabs/crusts, wool, and hides Especially if](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-22.jpg)
Prevention in Humans Avoid contact with infected animals, scabs/crusts, wool, and hides Especially if immunosuppressed Wear gloves When handling susceptible animals When vaccinating Wash hands
![Prevention in Animals Quarantine new animals Keep equipmentfomites clean Vaccination Live virus vaccine Only Prevention in Animals Quarantine new animals Keep equipment/fomites clean Vaccination Live virus vaccine Only](https://slidetodoc.com/presentation_image_h/c2ca585232d4be3167c57007c94cfe4f/image-23.jpg)
Prevention in Animals Quarantine new animals Keep equipment/fomites clean Vaccination Live virus vaccine Only used where infections have occurred in the past Isolate recently vaccinated animals Difficult to eradicate
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