Protein Sparing Effect Epin Norepin GH O 2

  • Slides: 32
Download presentation

能量代謝循環系統 (Protein Sparing Effect) 胰島素 升糖激素 葡萄糖 蛋白質 胺基酸 肝醣 脂肪酸 脂肪 酮體 Epin,

能量代謝循環系統 (Protein Sparing Effect) 胰島素 升糖激素 葡萄糖 蛋白質 胺基酸 肝醣 脂肪酸 脂肪 酮體 Epin, Norepin, GH 類固醇 氧氣O 2 ADP 能量 ATP 能量代謝 二氧化碳, 水, 尿素 Blackburn: Management of obesity by severe calorie restriction 1985

靜脈注射氨基酸 一般用途配方 ? E/T比(必須氨基酸／總氮量)＝ 3. 0 ? E/N比(必須氨基酸／非必須氨基酸)＝ 1 ? Increase Arginine ? Moriamin-SN

靜脈注射氨基酸 一般用途配方 ? E/T比(必須氨基酸／總氮量)＝ 3. 0 ? E/N比(必須氨基酸／非必須氨基酸)＝ 1 ? Increase Arginine ? Moriamin-SN 10% (中化) ? Decreased Glycine ? Aminosyn 10% (亞培) ? 低鈉低氯 (Lysine in added as the acetate) ? Aminol V 12 X(信東) ? Molar Ratio ? Teruamin 12%(Terumo) BCAAs to AAAs＝ 3. 0 -3. 5: 1 ? Amiparen 10%(Otsuka) ? BCAAs 23 -25% ? Aminoplasma 10% (B Braun)

靜脈注射氨基酸 重症營養用 高支鏈氨基酸配方 Ÿ Ÿ Ÿ Ÿ Fre. Amine HBC 6. 9% High Protein

靜脈注射氨基酸 重症營養用 高支鏈氨基酸配方 Ÿ Ÿ Ÿ Ÿ Fre. Amine HBC 6. 9% High Protein (5%) 45% BCAA Reduced Glycine E/T ratio = 4. 4 Elevated leucine HBC ratio (isoleucine: valine) 1. 0: 1. 8: 1. 3 Glucose infused at 5. 2 mg/kg/min 8. 5% Fre. Amine III Ÿ Normal protein (4. 25%) Ÿ 23% BCAA Ÿ Standard Glycine Ÿ E/T ratio = 3. 0 Ÿ Normal leucine Ÿ HBC ratio (isoleucine: valine) 1. 0: 1. 3: 1. 1 Ÿ Glucose infused at 7. 4 mg/kg/min

肝性腦病變 Hepatic Encephalopathy Blood Brain Barrier 肝 Brain Liver Protein intake 蛋白質攝取 腦 AAA

肝性腦病變 Hepatic Encephalopathy Blood Brain Barrier 肝 Brain Liver Protein intake 蛋白質攝取 腦 AAA MET NH 3 BCAA 肌肉

慢性肝病血漿不正常氨基酸圖 400 Glu % of Normal 350 Meth Asp Phe 300 250 Tyr 200

慢性肝病血漿不正常氨基酸圖 400 Glu % of Normal 350 Meth Asp Phe 300 250 Tyr 200 Try 150 Gly 100 Thr Val Leu 50 Lys Tau Orn Ser Pro Ala Ileu 必須氨基酸 非必須氨基酸 His Arg

特殊疾病氨基酸配方 肝臟疾病 ? 高支鏈氨基酸 High BCAA(36%) ? 低芳香環氨基酸 Low Aromatic A. A. ? BCAA:

特殊疾病氨基酸配方 肝臟疾病 ? 高支鏈氨基酸 High BCAA(36%) ? 低芳香環氨基酸 Low Aromatic A. A. ? BCAA: AAA＝ 37: 1(Molar ratio) ? Low Methionine ? Iso: Leu: Val ratio＝ 1: 1: 1 ? 完整蛋白質配製 (for liver disease)

早產兒 新生兒 氨基酸配方 Troph. Amine 10%/Aminovenos N-pad 10% 血漿氨基酸正常化 促進成長 Ü 高量必須氨基酸(包括tyrosine及histidine) Ü 低量phenylalanine,

早產兒 新生兒 氨基酸配方 Troph. Amine 10%/Aminovenos N-pad 10% 血漿氨基酸正常化 促進成長 Ü 高量必須氨基酸(包括tyrosine及histidine) Ü 低量phenylalanine, methionine, glycine Ü 含dicarboxylic amino acids (glutamic acid及aspartic acid) Ü 含taurine(為新生兒必須氨基酸) Ü 含N-acetyl-L-tyrosine(可溶性tyrosine) Ü 避免膽汁鬱積性黃疸cholestasis的發生

微量元素 Trace Elements Injection(CCPC)

微量元素 Trace Elements Injection(CCPC)

維生素注射液 Lyo-Povigen(CCPC)

維生素注射液 Lyo-Povigen(CCPC)

PROTEIN OUTLINE Protein Definition Protein structure Protein FunctionPROTEIN OUTLINE Protein Definition Protein structure Protein Function
Protein Simple Protein Conjugated Protein Derivative Protein SpecialProtein Simple Protein Conjugated Protein Derivative Protein Special
Protein Yaps Analizi Protein aileleri Protein lokalizasyonu proteinProtein Yaps Analizi Protein aileleri Protein lokalizasyonu protein
Protein Stability Protein Folding Protein Stability Protein stabilityProtein Stability Protein Folding Protein Stability Protein stability
MANAGEMENT VERIFICATIONS in SLOVENIA Mateja epin Train theMANAGEMENT VERIFICATIONS in SLOVENIA Mateja epin Train the
Raman Effect Raman Effect SmekalRaman Effect Raman EffectRaman Effect Raman Effect SmekalRaman Effect Raman Effect
Substitution Effect Income Effect Price Effect Substitution EffectSubstitution Effect Income Effect Price Effect Substitution Effect
Protein sequencing Determining protein sequences Why the proteinProtein sequencing Determining protein sequences Why the protein
Translation Protein Synthesis RNA protein Making a proteinTranslation Protein Synthesis RNA protein Making a protein
Protein structures Protein Structure Why protein structure TheProtein structures Protein Structure Why protein structure The
Protein Chemistry Basics Protein function Protein structure PrimaryProtein Chemistry Basics Protein function Protein structure Primary
Izolace protein Literatura Scopes Protein Purification Harris ProteinIzolace protein Literatura Scopes Protein Purification Harris Protein
Protein Folding Notes Protein Structure Protein Function InProtein Folding Notes Protein Structure Protein Function In
Protein Metabolism Protein Digestion Protein breakdown begins inProtein Metabolism Protein Digestion Protein breakdown begins in
Protein Notes Chemical structure of protein Protein isProtein Notes Chemical structure of protein Protein is
PROTEIN SYNTHESIS Jessica Hawley PROTEIN SYNTHESIS Protein SynthesisPROTEIN SYNTHESIS Jessica Hawley PROTEIN SYNTHESIS Protein Synthesis
Protein structure determination prediction Tertiary protein structure proteinProtein structure determination prediction Tertiary protein structure protein
Protein Metabolism Protein Digestion Protein breakdown begins inProtein Metabolism Protein Digestion Protein breakdown begins in
Denaturasi Protein Denaturasi protein yaitu nberubahnya sifat proteinDenaturasi Protein Denaturasi protein yaitu nberubahnya sifat protein
PROTEIN EGGS AND MILK PROTEIN Facts About ProteinPROTEIN EGGS AND MILK PROTEIN Facts About Protein
Protein Folding Processing and Degradation Protein Folding ProteinProtein Folding Processing and Degradation Protein Folding Protein
Protein sequences alignment and protein modeling Protein sequencesProtein sequences alignment and protein modeling Protein sequences
Protein BIOKIMIA 202198 BIOKIMIA Protein Protein terbentuk atasProtein BIOKIMIA 202198 BIOKIMIA Protein Protein terbentuk atas
SDSPAGE protein mixture single protein isolation SDSPAGE proteinSDSPAGE protein mixture single protein isolation SDSPAGE protein