Big picture of protein synthesis Transcription Translation Just

Big picture of protein synthesis

Transcription

Translation

Just Like Construction… • • • DNA is the master plan m. RNA is the everyday blueprint r. RNA is the builder t. RNA is the gopher Amino Acids are the wood Proteins are the building

Translation of the Genetic Code Protein Synthesis

This is a molecule of messenger RNA. m. RNA is transcribed in the nucleus. codon AUGGGCUUAAAG CAGUGCACGUU m. RNA molecule

A ribosome attaches to the m. RNA molecule. ribosome AUGGGCUUAAAG CAGUGCACGUU

Amino acid t. RNA molecule A transfer RNA molecule arrives. It brings a specific amino acid to the first three bases (codon) on the m. RNA. anticodon The three unpaired bases (anticodon) on the t. RNA link up with the codon. UAC AUGGGCUUAAAG CAGUGCACGUU

Another t. RNA molecule comes into place, bringing a second amino acid. Its anticodon links up with the second codon on the m. RNA. CC G UAC AUGGGCUUAAAG CAGUGCACGUU

Peptide bond A peptide bond forms between the two amino acids. U A CC C G AUGGGCUUAAAG CAGUGCACGUU

The first t. RNA molecule releases its amino acid and moves off into the cytoplasm. C A U CCG AUGGGCUUAAAG CAGUGCACGUU

The ribosome moves along the m. RNA to the next codon. CCG AUGGGCUUAAAG CAGUGCACGUU

Another t. RNA molecule brings the next amino acid into place. AA U CCG AUGGGCUUAAAG CAGUGCACGUU

A peptide bond joins the second and third amino acids to form a polypeptide chain. CCGCCG AUGGGCUUAAAG CAGUGCACGUU

The process continues. The polypeptide chain gets longer. This continues until a termination (stop) codon is reached. The polypeptide is then complete. AC G GUC AUGGGCUUAAAG CAGUGCACGUU

CODON TABLE

1. What amino acids would be coded by the following DNA sequence? CGGACCGCTATC 2. What would be the m. RNA sequence for a polypeptide chain (protein) that had the following amino acids? DNA sequence? Lysine-Cysteine-Proline