Big picture of protein synthesis Transcription Translation Just
Big picture of protein synthesis
Transcription
Translation
Just Like Construction… • • • DNA is the master plan m. RNA is the everyday blueprint r. RNA is the builder t. RNA is the gopher Amino Acids are the wood Proteins are the building
Translation of the Genetic Code Protein Synthesis
This is a molecule of messenger RNA. m. RNA is transcribed in the nucleus. codon AUGGGCUUAAAG CAGUGCACGUU m. RNA molecule
A ribosome attaches to the m. RNA molecule. ribosome AUGGGCUUAAAG CAGUGCACGUU
Amino acid t. RNA molecule A transfer RNA molecule arrives. It brings a specific amino acid to the first three bases (codon) on the m. RNA. anticodon The three unpaired bases (anticodon) on the t. RNA link up with the codon. UAC AUGGGCUUAAAG CAGUGCACGUU
Another t. RNA molecule comes into place, bringing a second amino acid. Its anticodon links up with the second codon on the m. RNA. CC G UAC AUGGGCUUAAAG CAGUGCACGUU
Peptide bond A peptide bond forms between the two amino acids. U A CC C G AUGGGCUUAAAG CAGUGCACGUU
The first t. RNA molecule releases its amino acid and moves off into the cytoplasm. C A U CCG AUGGGCUUAAAG CAGUGCACGUU
The ribosome moves along the m. RNA to the next codon. CCG AUGGGCUUAAAG CAGUGCACGUU
Another t. RNA molecule brings the next amino acid into place. AA U CCG AUGGGCUUAAAG CAGUGCACGUU
A peptide bond joins the second and third amino acids to form a polypeptide chain. CCGCCG AUGGGCUUAAAG CAGUGCACGUU
The process continues. The polypeptide chain gets longer. This continues until a termination (stop) codon is reached. The polypeptide is then complete. AC G GUC AUGGGCUUAAAG CAGUGCACGUU
CODON TABLE
1. What amino acids would be coded by the following DNA sequence? CGGACCGCTATC 2. What would be the m. RNA sequence for a polypeptide chain (protein) that had the following amino acids? DNA sequence? Lysine-Cysteine-Proline
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