INTRODUCTION TO PATHOLOGY Dr Heyam Awad MD FRCPATH

INTRODUCTION TO PATHOLOGY Dr Heyam Awad MD, FRCPATH, Jordanian Board LECTURE 1

Introduction to pathology

Today’s lecture • Introduction aiming at: 1. Introducing you to the course. 2. What is pathology ? 3. What do pathologists do?

The course • Two credit hours course • Three main subjects will be covered: 1. Cell injury 2. Inflammation 3. Neoplasia

reference - Robbins basic pathology, Kumar Abbas and Aster, 10 th edition. - My slides are a summary of the book!

Course design! topic instructor No of lectures Book chapter Cell injury Dr Heyam Awad 5 1 Inflammation and repair Dr Mousa Abbadi 10 2 neoplasia Dr Maha shomaf 10 5

My lectures • Two sets of slides: • 1. A detailed one which you need to study from This will be on my web page and on the e learning site before the lecture day. 2. A FUN version that includes mainly pictures. . This will aid us discussing the subject Do we need sheets? . . How to study?

assessment *Mid term. . 40 marks. . Around week 7 material: cell injury and inflammation *Final exam. . 50 marks material: repair and neoplasia *Attendance marks. . 10 please note: school of medicine is strict about attendance. .

The best way to deal with my lectures! • 1. attend the lectures and try to understand • 2. read the slides carefully. . They are detailed. . I put everything you need for the exam there • 3. I encourage you to read the book: chapter 1 • 4. keep checking the e-learning, I’ll put resources and sample questions there. • KEEP CALM AND ENJOY

MY RULES!!! • First: your rights • To be respected • To enjoy each 50 minutes here • To understand • And: please ask questions. . Give comments. . And challenge me!

Remember:

Lecture RULES: your duty! • Give me your full attention!

What about coffee?

Contact details • Office hours: 2 -3 daily • My office is in the hospital, third floor • You can also see me outside the office hours, if I’m not in the office I’ll be in the histopathology department in the same floor(third) • E mail: h_awad@ju. edu. jo • : heyamawad 2000@yahoo. com • Also: keep checking e learning for announcements.

What is pathology? • Patho = disease • Logy = study • So pathology is the study of disease = ﻋﻠﻢ ﺍﻻﻣﺮﺍﺽ

Pathology studies three main aspects of the disease process: • Etiology • Pathogenesis • morphology

Etiology. . The “why” question • = the origin of disease= the underlying cause.

Pathogenesis. . “HOW” • Steps in the development of disease. • Describes how etiologic factors trigger cellular and molecular changes that give rise to functional and structural abnormalities. • Disease occur in a multistep organized fashion. .

pathogenesis • Message: as a doctor you need critical thinking, splitting things into precise steps and stages

morphology • The changes seen on tissues and organs that help diagnosing the disease • Gross= macroscopic morphology: changes seen by naked eye • Microscopic morphology: changes seen under the microscope.

Gross morphology. . Can you describe ?

morphology

Histopathology is fun. .

What do pathologists do?

Sample obtained. . how

Sample received in lab

HOW DOES THESE SAMPLES CHANGE INTO GLASS SLIDES? ? ?

Grossing = cutting the sample

Processing to a paraffin block

Cutting. . By a microtome

Staining the slide

Ready to be read by the pathologist

The pathology report • We convey what we see under the microscope in a written report. • The report includes macroscopic ( gross) and microscopic description. • It gives you information about: the diagnosis, the prognosis and probably the underlying cause.