Medical Dosage Calculation A Dimensional Analysis Approach Tenth






































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Medical Dosage Calculation A Dimensional Analysis Approach Tenth Edition 8 CHAPTER Preparation of Solutions Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Directory • Classroom Response System Questions • Lecture Note Presentation Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Classroom Response System Questions Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #1 If a 25% solution is diluted, what might be the strength of the resulting solution? Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #1 Choices 1. 2. 3. 4. 50% 25% 10% 75% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #1 Response 1. 2. 3. 4. 50% 25% 10% 75% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #2 If a 1: 69 solution is diluted, what might be the strength of the resulting solution? Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #2 Choices 1. 2. 3. 4. 1: 30 1: 90 2: 120 3: 12 Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #2 Response 1. 2. 3. 4. 1: 30 1: 90 2: 120 3: 12 Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #3 If 1 liter of a solution contains 100 grams of pure drug, what is the strength of this solution as a fraction, ratio, and as a percentage? Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #3 Choices 1. 2. 3. 4. 1/100 strength, 1: 100, 1% 1/1000 strength, 1: 1000, 0. 1% ½ strength, 1: 2, 50% 1/10 strength, 1: 10, 10% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #3 Response 1. 2. 3. 4. 1/100 strength, 1: 100, 1% 1/1000 strength, 1: 1000, 0. 1% ½ strength, 1: 2, 50% 1/10 strength, 1: 10, 10% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #4 The strength stated on a drug label is 100 mg/m. L. Write this strength in the form of a percentage. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #4 Choices 1. 2. 3. 4. 500% 5% 10% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #4 Response 1. 2. 3. 4. 500% 5% 10% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #5 The physician orders minoxidil (Rogaine) 2%; apply 2 m. L to scalp b. i. d. How many milligrams of minoxidil will be applied to the scalp with each dose? Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #5 Choices 1. 2. 3. 4. 40 mg 4 mg 5 mg 2 mg Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Question #5 Response 1. 2. 3. 4. 40 mg 4 mg 5 mg 2 mg Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Lecture Note Presentation Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Learning Outcomes 1. Describe the strength of a solution as a ratio, fraction and as a percent. 2. Determine the amount of solute (drug) in a given amount of solution. 3. Determine the amount of solution that would contain a given amount of solute (drug). 4. Do the calculations necessary to prepare a solution from a solute. 5. Do the calculations necessary to prepare solutions for irrigations, soaks, and nutritional feedings. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Strength of a Solution Examples of strength using stated units of measurement: Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Strength of a Solution • Solution strength can also be stated without explicit units of measurement. For example, a solution which is 1 part iodine in 2 parts of solution has strength of: 1: 2 Ratio Fraction 50% Percent Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Strength of a Solution • Measure the Amount of Drug (Solute) in either g or m. L • Measure the Amount of the Solution in m. L 1: 100 Na. Cl solution has 1 g Na. Cl in 100 m. L of the solution 1/3 strength solution of Iodine has 1 m. L of Iodine in 3 m. L of solution. 7% magnesium sulfate solution has 7 g magnesium sulfate in 100 m. L of solution Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Find the Strength • What is the strength of a 500 milliliter solution that contains 50 m. L of iodine? 1 = 50 m. L 500 m. L 10 The strength is 1: 10, 1/10 strength, or 10% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Find the Strength • What is the strength of a 200 milliliter solution that contains 50 g of Na. Cl? 1 = 50 g ------200 m. L 4 The strength is 1: 4, ¼ strength, or 25% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Find the amount of solute in a given amount of solution of known strength • How many grams of dextrose would you need to prepare 1000 milliliters of a 5% solution? Amount of solution is 1, 000 milliliters. Strength is 5% This means Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Convert 1, 000 m. L of solution to g of dextrose 50 g So, you need 50 grams of dextrose to prepare 1, 000 milliliters of a 5% solution. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Finding the Amount of Solute • How would you prepare 250 milliliters of a 1/2% creosol solution? Creosol comes in liquid form. Amount of solution is 250 milliliters. Strength is ½% or 0. 5% This means Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Convert 250 m. L solution to ? m. L of Creosol =1. 25 m. L Creosol So, 1. 25 milliliters of creosol is diluted with water to 250 milliliters of solution. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Find the amount of solution of known strength containing a given amount of solute • How many milliliters of a 20% magnesium sulfate solution will contain 40 grams of the solute magnesium sulfate? You want to convert the 40 grams of pure drug to milliliters of solution. 40 g = ? m. L Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
In a 20% solution, there are 20 grams of solute per 100 m. L of solution. So, the strength is 2 200 m. L 1 So, 200 m. L of a 20% magnesium sulfate solution contains 40 g of magnesium sulfate. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Finding the Amount of Solute • How many ounces of full-strength Sustacal are needed to make 16 ounces of ¼ strength Sustacal? Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
16 oz Solution = ? oz Sustical 4 = 4 oz 1 So, 4 oz of full-strength Sustical are needed to make 16 ounces of ¼ strength Sustical. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Chapter Summary • The strength of a solution is the ratio of the amount of solute dissolved in the solution to the total volume of the solution. • The strength of a solution may be expressed in the form of a ratio, fraction, or percentage. • A 1/2 strength solution is a 1: 2 or a 50% solution, and should not be confused with a 1/2 % solution. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Chapter Summary • The amount of solute dissolved in the solution should be expressed in milliliters if the solute is a liquid. • The amount of solute dissolved in the solution should be expressed in grams if the solute is a solid or powder. • The volume of a solution should be expressed in milliliters. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Chapter Summary • To determine the amount of solute contained in a given amount of a solution of known strength, use the strength as the known equivalence. • To determine amount of a solution of known strength containing a given amount of solute, use the strength as the known equivalence. Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Chapter Summary • The strength of a particular solution may be written in many different forms. The following strengths are all equivalent: • With stated Units of Measurement Rates { Equivalence 500 mg = 1 m. L Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.
Chapter Summary • Without stated Units of Measurement Fraction Ratio Percentage 1/2 strength 1: 2 50% Medical Dosage Calculations: A Dimensional Analysis Approach, Tenth Edition June L. Olsen • Anthony P. Giangrasso • Dolores Shrimpton Copyright © 2012, © 2008 by Pearson Education, Inc. All rights reserved.






































