Ph D Programme 20172018 Palack University Faculty of

Ph. D Programme 2017/2018 Palacký University Faculty of Medicine and Dentistry, Olomouc Czech Republic Exploiting Literature Databases English Version Course teacher & developer: J. Potomková, Ph. D. jarmila. potomkova@upol. cz Clinical Advisor: Prof. Vladimír Mihál, MD. Ph. D. Palacky University Department of Paediatrics & Institute of Medical Biophysics E-learning materials http: //biomedicina. upol. cz/moodle

Course Structure • Introduction – – – Contacts Usefull links Electronic information resources at Palacký University Olomouc • • • Research question Information retrieval using multiple resources – – • • Remote access Theory Interactive online training Discussion, exercise Conclusion.

Contacts Jarmila Potomková, Ph. D. Palacký University Olomouc Institute of Medical Biophysics and Department of Paediatrics Information Specialistr jarmila. potomkova@upol. cz Vladimír Mihál, Prof. , MD. , Ph. D. Palacký University & Teaching Hospital Department of Paediatrics, Professor mihalv@fnol. cz „QAKOM“ – e-learning portal for Ph. D programmes http: //biomedicina. upol. cz/moodle -- Kurzy/B 001/

Useful Links • Palacký University Library, Olomouc http: //katalog. upol. cz Online public access catalog • Research Library, Olomouc http: //www. vkol. cz. • National Medical Library, Prague http: //www. nlk. cz – Fee-based registration for remote database access http: //www. medvik. cz/bmc – Bibliographia Medica Čechoslovaca • National Library of Medicine (USA) http: //www. locatorplus. gov http: //www. pubmed. gov – Database MEDLINE. • Search Engines http: //www. google. com - General search http: //scholar. google. com - Scientific articles only http: //books. google. com - Book content for reading only http: //www. yahoo. com http: //www. bing. com

Electronic Information Resources at Palacký University • ABC, faculties, domains (subjects) http: //ezdroje. upol. cz • Medical + multidisciplinary databases – Free (Pub. Med http: //www. pubmed. gov) – IP-recognition • • Palacký University network (eg. Web of Knowledge http: //isiknowledge. com) Teaching Hospital Olomouc (eg. Dynamed http: //search. epnet. com; Up. To. Date http: //www. uptodate. com/online; Scopus http: //www. scopus. com – Remote access • • VPN (Virtual Private Network) https: //wiki. upol. cz/upwiki/Pristup_k_pocitacove_siti/en Terminal Server For more details and technical assistance feel free to contact: Mr. Tomáš Kopečný, network administrator (tomas. kopecny@upol. cz)

Research Question Neurodegenerative disorders and the neuronal intracellular transport.

Search terms, keywords „Minimum Information Principle“ Problem • Neurodegenerative diseases/disorders • Alzheimer´s disease Intervention • Neural intracellular transport/traffic • Intracellular transport/traffic of neurons

Multiple Resources

• Electronic library catalogs • Internet search engines • Professional databases • Medical + multidisciplinary

Electronic Library Catalogs Czech Uniform Information Gateway http: //www. jib. cz Navigation, functions: Search query structure: Quick Search - Advanced All Fields -- • neurodegenerat* And • intracellular transport Foreign books

Search Engines http: //www. google. com http: //www. yahoo. com http: //www. bing. com

Medical Websites Quality e. Europe 2002: Quality Criteria for Health related Websites Communication from the Commission to the Council, the European Parliament, the Economic and Social Committee and the Committee of the Regions Free access

Medical Websites Quality Basic Criteria • • • Transparency and Honesty Authority Privacy and data protection Updating of information Accountability Accessibility

INTERNET Deep Web Search Engines : Scholar Google http: //www. scholar. google. com Navigation and functions: Journal articles Advanced Search • Cited by • Related articles • Versions All words: intracellular transport At least one of the words: neurodegenerative neurodegeneration Alzheimer Occurrence: article title Date: after 2010

Professional Medical + Multidisciplinary Databases : Selection MEDLINE/Pub. Med • • Medical bibliographic database with fulltext links Free access to bibliographic content WEB OF KNOWLEDGE • • Multidisciplinary bibliographic database with fulltext links Access by IP-recognition (Palacky University Olomouc Network) SCOPUS • • Multidisciplinary bibliographic database with fulltext links Access by IP-recognition (Palacky University + University Hospital Olomouc Networks) Dyna. Med • • Point-of-care EBM knowledgebase with some fulltexts Access by IP-recognition (Palacky University + University Hospital Olomouc Networks) Up. To. Date • • EBM knowledgebase Access by IP-recognition (Palacky University + University Hospital Olomouc Networks) COCHRANE LIBRARY • • Systematic reviews Access by IP-recognition (Palacky University Olomouc Networks)

MEDLINE/Pub. Med http: //www. pubmed. gov Advanced Search

MEDLINE/Pub. Med „Gold Standard“ for biomedical and health sciences Free access to bibliographic data Produced by: National Library of Medicine, Bethesda/MA, USA Coverage: • >5000 journals published in the USA a 80 other countries • > 28 mill. records, retro since 1950 All records have English abstracts irrespective of original languages • Summary + abstract + Me. SH terms • Fulltext links from journal providers • Link. Out – More Resources • Free • Institutional licence/subscription • Absent /some archival materials

Search Tools Boolean Operators AND, OR, NOT Documents must contain at least two (or more) search terms q intracellular AND transport Documents must contain any (or all) of search terms q neurodegeneration OR Alzheimer* Documents must not contain search terms q neurodegeneration NOT surgery

Pub. Med: Search Strategy URL: http: //www. pubmed. gov --- Advanced Search Builder tools Boolean operators OR, AND, NOT Truncation/wildcards * Occurrence of terms in different fields Step #1 Title: neurodegenerati* (search term occurs in article title) OR Title: Alzheimer* (search term occurs in article title) Add to History Step #2 Title/abstract: intracellular transport (search terms occur in article title/or abstract) OR Title/abstract: intracellular traffic* (search terms occur in article title/or abstract) Add to History Step #3 Title/Abstract: neuron* History #1 AND #2 AND #3 Search

Pub. Med : Results • Summary • Abstract – Related articles – Send to : • File • E-mail (fulltext delivery library services) – Article types, Me. SH Terms (Medical Subject Headings) – Linkout – more resources – Free fulltext – Providers, publishers – fee, subscription – Absent

Send to == Email REMINDER: Additional text must contain your contact. Fulltext delivery: Contact Medical Library staff: daniela. smolikova@upol. cz

Medical Knowledgebases for Evidence-Based Medicine – EBM • Dyna. Med • Up. To. Date

http: //search. epnet. com

Access: • IP-recognition within Palacký University and University Hospital Olomouc networks • Remote access • A point-of-care reference tool with clinically-organized summaries for more than 3, 200 topics • Monitors up to 500 medical journals and systematic evidence review databases through journal review services. • Each article is evaluated for clinical relevance and scientific validity, and the new evidence is then integrated with existing content, with overall conclusions being drawn from the best available evidence. • Daily updates • „Search within text“ tool - keyword search • „Levels of evidence“ – validity • References including reviews and guidelines

http: //www. uptodate. com/online

Access: • IP-recognition within Palacký University and University Hospital Olomouc networks • Remote access • Evidence-based clinical summaries, quarterly updated >10, 500 critically appraised topics • 25 specialties • Monitors about 460 journals • Text + graphics + Pub. Med links • • • References Guidelines Patient information

Multidisciplinary Bibliographic Databases • Scopus • Web of Knowledge

SCOPUS http: //www. scopus. com

SCOPUS Access: • • IP-recognition within Palacký University and University Hospital Olomouc networks Remote access • > 60 mill. records of scientific articles published in about 21, 500 peerreviewed journals and 113, 000 books. • Records can have fulltext links to publishers´ websites. Full access depends on valid institutional licences. • Produced by Elsevier Science, retro since 1960 s´ • Subject coverage: sciences – technology – medicine – humanities and arts.

SCOPUS Search tools: Boolean operators: OR, AND, NOT, phrases in „double Truncation (wildcard) * Keyword occurrence in different fields quotes“ Document Search Template Step #1 Article title/neurodegenerati* OR Alzheimer* AND Step #2 Title-Abs-Key/„intracellular transport“ OR „intracellular trafficking“ AND Step 3 Title-Abs-Key/neuron* Document Search Results Display fulltextts = View at Publishers – depends on valid institutional licences Advice: verify fulltext availability through https: //scholar. google. com

WEB OF KNOWLEDGE http: //isiknowledge. com

WEB OF KNOWLEDGE ACCESS • IP-recognition within Palacký University and University Hospital Olomouc networks • Remote access • > 1 miliard records of scientific articles, conference proceedings and book chapters published in about 12, 000 peer-reviewed primary publications. • Records can have fulltext links to publishers´ websites. Full access depends on valid institututional site licences. • Produced by Thomson Reuters, retro since 1946 • Subject coverage: sciences – technology – medicine – arts and humanities.

WEB OF KNOWLEDGE INTEGRATED ACCESS TO 10 DATABASES: Web of Science Core Collection Current Contents Connect Derwent Innovations Index MEDLINE Sci. ELO Citation Index (Hispanic) BIOSIS Citation Index Data Citation Index Korean Journal Database Russian Science Citation Index Zoological Records Module JOURNAL CITATION REPORTS offers access to journal impact factors.

WEB OF KNOWLEDGE Search tools: Boolean operators: OR, AND, NOT, proximity operator NEAR Truncation (wildcard) * Keyword occurrence in different fields (Title, Topic) Search Query Structure Step #1 Title/neurodegenerati* OR Alzheimer* Add another field AND Step #2 Topic/(intracellular NEAR/2 transport) OR (intracellular NEAR/2 traffic*) Add another field AND Step 3 neuron* SEARCH Step 4 Sort Results by Times Cited Highest to Lowest Full text from Publisher – depends on valid institutional licences.

Discussion, exercise Use WEB OF KNOWLEDGE to find out journal impact factors Navigation: http: //isiknowledge. com • Journal Citation Reports