CRO 1 Functional Food 2 Medical Food Nutraceutical

미국 식품회사 CRO가 인식하는 중요 연구분야 1. Functional Food 2. Medical Food, Nutraceutical Food Safety Natural Food Organic Food Low Fat and Modified Fat Composition 3. 4. 5. 6. Source : Food Technology, Vol 54, 2000.

Over the next three years, which industries will enjoy the best growth prospects? Healthcare, pharmaceuticals and biotechnology l Aerospace and defense l Telecoms, software and IT services l 69% 40% 33% (Respondents could choose as many answers as applied. ) Source : Economist Intelligence Unit online survey, Oct-Dec 2002. (03 -Mar, 2003)

USA의 건강기능식품 기술동향 l NLEA (1990) – Health Claims (일반식품에 허용) 1. 칼슘과 골다공증 – – high calcium , Low-fat milk, yogurt, tofu, calcium-fortified citrus drinks calcium supplements 나트륨과 고혈압 2. – – Low Sodium Unsalted tuna, salmon, fruits and vegetables, low-fat milk, cereal 식이지방과 암 3. - Low Fat Fruits, vegetables, reduced-fat milk products, cereals, flours 포화지방 및 콜레스테롤과 관상동맥심질환 4. – – Low saturated fat, Low cholesterol, Low fat Fruits, vegetables, skim and low-fat milks, cereals, pastas(not egg pastas)

USA의 건강기능식품 기술동향 섬유소 함유 곡류, 과일 및 야채와 암 5. – – Good source of dietary fiber, Low fat Whole-grain breads, cereals, fruits, vegetables 섬유소 함유 과일, 채소 및 곡류와 관상동맥 심질환 6. – – > 0. 6 g soulble fiber, Low fat, Low cholesterol Fruits, vegetables, whole-grain bread, cereals 과일 및 채소와 암 7. – – Low fat, Good source of fiber, Vit A, Vit C Fruits and vegetables 엽산과 신경관 결함 8. – – > 40 mg folic acid per serving Enriched cereal grain products, some legumes, orange, Grape fruit, dietary supplements, fortified breakfast cereals

USA의 건강기능식품 기술동향 당 알콜과 충치 9. – – 귀리의 수용성섬유소와 관상동맥 심질환 10. – – > 0. 75 g oat soluble fiber per serving, Low fat, Low choleste. Oatmeal cookies, muffins, brealds, cereals, dietary supplem. 대두단백과 심장관상동맥 심질환 11. – > 6. 25 g soy protein, Low fat, Low cholesterol, Low saturated fat 식물성 스테롤 및 스타놀 에스테르와 심장관상동맥 심질환 12. l xylitol, sorbitol, erythritol, mannitol, > p. H 5. 7 Sugarless candy and gum – > 0. 65 g plant sterol ester, > 1. 7 g plant stanol ester – Salad dressing, snack bars, dietary supplement Significant scientific agreement 평가로 허용

FDA proposed Rule for Dietary Supplement Current Good Manufacturing Practices (CGMPs) l Action 07 March, 2003 l Since 1993, received 7, 000 adverse report l Misbranding or Adulteration l Mandatory standards for Manufacturing or Labeling l Apply both domestic and foreign firms l 3 -year phase-in of a final rule for small businesses

Japan의 건강기능식품 기술동향 l 특정보건용식품 – (7개 기능, 13개 표시 허용) 1. 장의 상태를 조절 (fiber, oligosacharide, lactobacillus) 2. 콜레스테롤 조절 (peptide, dietary fiber, protein) 3. 혈압조절 4. 미네랄흡수개선(CPP, CCM, Heme Fe, peptide) 5. 충치관련 6. 중성지방관련 (indigestible dextrin) 7. 혈당조절 (soy protein, soluble dietary fiber, peptide) (peptide, glycoside) (sugar alcohol, polyphenol)