HHV 014 NUTRACEUTICAL FORMULATION TECHNOLOGY 8 4 FILM

HHV ⁵ 014 NUTRACEUTICAL FORMULATION TECHNOLOGY 8. 4 FILM COATING FATIN FAIROZA FADHILAH IZZATI

INTRODUCTION ▪ A film coating is a thin polymer-based coat applied to a solid

Purpose To control site of dissolution To mask unpleasant taste Improving product stability To

Type of film coating ▪ Conventional film coating ▪ Apply to improve product appearance.

Factor affecting quality of film coating Interaction between the core material (substrate) and the

Coating Equipment Perforated pan Spray dry Fluidize bed

Conclusion ▪ Film coating technology is now days very important in the nutraceutical technology,

Slides: 7

Download presentation

HHV ⁵ 014 NUTRACEUTICAL FORMULATION TECHNOLOGY 8. 4 FILM COATING FATIN FAIROZA FADHILAH IZZATI HUSNA

INTRODUCTION ▪ A film coating is a thin polymer-based coat applied to a solid dosage form such as a tablet, granule or other particle. The thickness of such a coating is usually between 20 and 100 µm. ▪ Film-coating formulations usually contain the following components: Polymer. Plasticizer. Pigment/opacifier. Vehicle.

Purpose To control site of dissolution To mask unpleasant taste Improving product stability To provide a controlled rate absorption Modifying drug-release characteristics

Type of film coating ▪ Conventional film coating ▪ Apply to improve product appearance. ▪ Improve stability ▪ Ease of swallowing ▪ Modified release film coating ▪ Effectively used either to sustain the release (extended release) or delay the release (enteric coating) of drug. ▪ Sustained release film coating ▪ Act a membrane that allow infusion of fluid ▪ Application: Encapsulation & Tableting ▪ Enteric film coating ▪ Drug delivery system to pass through the stomach intact and dissolve upon reaching the intestine.

Factor affecting quality of film coating Interaction between the core material (substrate) and the applied coating. The drying process. The uniformity of distribution of the coating.

Coating Equipment Perforated pan Spray dry Fluidize bed

Conclusion ▪ Film coating technology is now days very important in the nutraceutical technology, particularly in formulation development. Process parameter and coting composition play important role in coating tablet. ▪ So, in order to get good quality of coated tablets it would be necessary to optimize parameter.