Premedication Dr M Kannan MD DA Professor And














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Premedication Dr. M. Kannan MD DA Professor And HOD Department of Anaesthesiology Tirunelveli Medical College
Premedication • Drugs administer 1 -2 hours before induction of Anaesthesia
Why Premedication • To Allay anxiety and fear • Non Pharmacological -Assurance &Raport – Pharmacological -Benzodiazepanies -Diazepam -Medazolam -Lorozepam
Why Premedication • To Reduce Secretion • Salivary secretion • Broncheal secretion • Anticholinergic drug-Atropine -Glycopyrolate Tachycardia Hyperthermia
Why Premedication • Enhances Hypnotic effect of General Anaesthetic Drugs -Less amount volatile Anaesthetics and nacotics
Why Premedication • Reduces Postoperative Nausea and Vomiting • Aspiration • Psychological trauma
To Prevent Vomiting • Metachlorpropamide • Ondansetron • Ranitidine
Why Premedication • Produce Amnesia • Benzodiazepine group -Diazepam 0. 1 -0. 2 mg/kg -Medazolam 0. 05 mg/kg -Lorozepam
Why Premedication • Gastric Content Volume ph -alkaline • Metoclopramide • Sodium citrate
Why Premedication • Attenuate sympathetoadrenal response -Laryngoscopy
Why Premedication • Attenuate vagal reflex • ? Bradycardia • Traction of eye muscle in squint surgery - Repeated administration succinylcholine -Induction of Anaesthesia with halothane -Lighter plane of Anaethsia
Why Premedication • Allay anxiety and fear • Reduce Secretion • Enhances Hypnotic effect of General Anaesthetic Drugs • Reduces Postoperative Nausea and Vomiting • Produce Amnesia • Gastric Content Volume ph -alkaline • Attenuate vagal reflex • Attenuate sympathetoadrenal response
What Drugs ? • Antisailagoge –Atropine/Glycopyrolate • Sedative –Morphine -Pethedine -Benzodiazepaines -Barbiturates Antiemitics -Metachlorpropamide/Ondonsetron • Disease Specific Drugs
Can we Give Fixed Pre. Med NO Cardiac –Avoid anticholinergics & Stiff sedatives Thyrotoxicosis- Avoid anticholinergic Head injury- Avoid sedatives Airway obstruction- Aviod sedatives Pregnancy- Avoid sedatives














