Mendelian Genetics Genetics and heredity For a long
- Slides: 24
Mendelian Genetics
Genetics and heredity For a long time, general ideas of inheritance were known + =
+ = What was really lacking was a quantitative understanding of how particular traits were passed down to their offspring.
Gregor Mendel (1822 -1884) • German monk born in 1822 • Lived in what is now the Czech Republic • Tended the garden at his monastery, conducted experiments with pea plants • Studied peas for 7 years, published results 1866; ignored until 1900 • Now considered the “Father of Genetics”
What is a trait? • A trait is a characteristic that can vary from one individual to the next (e. g. , eye color) • Mendel chose 7 pea plant traits to study: – seed shape, seed color, flower color, pod shape, pod color, flower position, plant height • He was lucky that each trait happened to be located on different chromosomes (people didn’t know about chromosomes back then)
Mendel's experiments • First, he created true (pure) breeding pea plants • Then he experimented with different traits (one at a time) – He cross-pollinated plants with different traits, and observed the offspring (Normally done by bees… Mendel used scissors and a paint brush)
Important vocabulary • True (pure) breeding = offspring always have same trait as parent (every time, no matter what!) • Self-pollination = plant fertilizes itself • Cross-pollination = one plant fertilizes another • P generation = Parent generation • F 1 generation = 1 st generation offspring (“filius” is Latin for “son”; offspring of P generation) • F 2 generation = 2 nd generation offspring (offspring of F 1 generation)
Mendel’s crosses • When Mendel crossed true-breeding tall plants with true-breeding dwarf plants (P generation)… …what size were the offspring (F 1 generation)?
• The F 1 generation were all tall
Mendel was surprised! • Mendel had expected the traits to blend: tall + dwarf = medium • Instead, the tallness of parent had masked the shortness of the other parent tall + short = tall? ?
• Mendel then let the F 1 generation self-pollinate to create the F 2 generation …what size were the offspring (F 2 generation)?
• Some of the F 2 offspring were tall, and some were dwarf • The ratio was always 3 tall to 1 dwarf (3: 1)
Mendel's findings • When Mendel crossed true-breeding plants with different traits, all of the F 1 plants showed only one trait (e. g. , all tall); the F 2 plants showed a 3: 1 ratio • He did not get “medium” plants! • He called the traits dominant (showed in F 1 generation) or recessive (didn’t show up in the F 1 generation)
Mendel’s conclusions Mendel realized that: 1. Inheritance of traits is controlled by genes contributed by each parent (e. g. , flower color)
Mendel’s conclusions 2. These genes come in different forms, called alleles (e. g. , purple or white flowers)
Mendel’s conclusions 3. Some alleles are dominant while others are recessive – When both types of alleles are present, dominant alleles mask (cover up) recessive alleles Mendel’s Discoveries & Results
Mendel’s Law of Dominance: • Generally, one allele is dominant to another • Dominant allele always expressed, even if combined with recessive allele – written as uppercase letter of the trait – e. g. , tall = dominant: TT, t. T, or Tt • Recessive allele expressed only if dominant allele is not present. – written as a lowercase letter of the dominant trait – e. g. , dwarf = recessive: tt
More vocabulary… • Genotype = genetic combination of alleles (e. g. , TT, Tt, tt) • Phenotype = physical characteristic or trait (e. g. , tall, short) • Homozygous = both alleles are the same (e. g. , TT or tt) → “true breeding” • Heterozygous = alleles are different (e. g. , Tt) • Hybrid = offspring of crosses of parents with different traits (e. g. , offspring of TT and tt)
Mendel’s Law of Segregation • When gametes form, the alleles from each parent are segregated (separated) from each other • Each gamete carries a single allele for each gene
Parents (P) gametes F 1 gametes F 2 Probability of F 2 generation being TT?
Punnett Squares • Instead of doing all of that hard work for each of the possible outcomes under the Law of Segregation, we can do a Punnett Square (geneticist Reginald Punnett created it) Father's Gametes Mother’s Gametes T t TT Tt Tt tt There is a 1 in 4 chance of the offspring being TT There is a 2 in 4 chance of the offspring being Tt There is a 1 in 4 chance of the offspring being tt 3 out of 4 plants = tall 1 out of 4 plants = dwarf Tall to dwarf = 3: 1
Mendel’s Law of Independent Assortment • Genes for two different traits are inherited independently • There is no connection between them (e. g. , plant height and seed color) Animation
- Family resemblance test
- Genetics is the study of heredity and variation
- Chapter 17 lesson 2 heredity and genetics
- Is baldness a sex linked trait
- Section 11-4 meiosis answer key
- Heterozygous for blood type a
- Extending mendelian genetics chapter 7
- Section 11-3 exploring mendelian genetics
- Chapter 10 section 2 mendelian genetics
- Mendelian genetics punnett square
- 11-3 exploring mendelian genetics answers
- 11.3 exploring mendelian genetics
- Karyotype
- Pprr x pprr punnett square
- Section 11-3 exploring mendelian genetics
- Multiple alleles
- Identify the disorder
- Incomplete dominance meaning
- Codominace
- Mendel experiments in plant hybridization
- Chapter 10 sexual reproduction and genetics
- Mendelian inheritance pattern
- Mendelian genetics vocab
- What does incomplete dominance mean
- How to do a punnett square for color blindness