Louisiana Cancer Facts Figures All Cancer Sites Louisiana

Louisiana Cancer Facts & Figures, All Cancer Sites Louisiana Tumor Registry October, 2017

All Cancer Sites • Between 2010 and 2014, the average annual incidence rate# of all cancer sites in Louisiana was the 5 th highest and the mortality rate was the 4 th highest in the U. S. 1 • About 24, 220 new cancers are expected to be diagnosed and about 9, 240 patients are expected to die of cancer in Louisiana in 2017 2. # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. 1. Data source: NCI state cancer profile. 2. Data source: American Cancer Society, Cancer Facts & Figures 2017.

Common Cancers with Highest Incidence Rate#, 1 in Louisiana, 2010 -2014 Prostate (Male) 144. 4 Breast (Female) 123. 2 Lung & Bronchus 70. 5 Colon & Rectum 47. 8 Breast (in situ) (Female) 25. 2 Kidney & Renal Pelvis 21. 6 Non-Hodgkin Lymphoma 20 Uterus (Corpus & Uterus, NOS) (Female) 19. 1 Bladder 18. 8 16. 4 Childhood (Ages <20, All Sites) 0 20 40 60 80 # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. 1. Data source: NCI state cancer profile 100 120 140 160

All Cancer Sites: Age-Specific Incidence Rates#, Louisiana, 2010 -2014 3500 White Male Rate Per 100, 000 2800 White Female Black Male 2100 Black Female 1400 700 0 15 -19 25 -29 35 -39 45 -49 55 -59 Age at Diagnosis # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. 65 -69 75 -79 85+

All Cancer Sites: Age-Specific Incidence Rate# by Gender, 2010 -2014 3500 LA Male US Male Rate Per 100, 000 2800 LA Female US Female 2100 1400 700 0 15 -19 25 -29 35 -39 45 -49 55 -59 Age at Diagnosis # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. U. S. data source: 18 SEER registries. 65 -69 75 -79 85+

All Cancer Sites: Age-Specific Incidence Rates# by Race, 2010 -2014 2500 LA Whites Rate Per 100, 000 2000 US Whites LA Blacks 1500 US Blacks 1000 500 0 15 -19 25 -29 35 -39 45 -49 55 -59 Age at Diagnosis # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. U. S. data source: 18 SEER registries. 65 -69 75 -79 85+

All Cancer Sites: Incidence Rates #, 1, 2, , 2010 -2014 LA 700 Rate Per 100, 000 600 500 US 12% 617. 5 11% 551. 4 549. 7 497. 1 5% 417. 9 421. 5 416. 7 400 397. 4 300 200 100 0 White Male White Female Black Male # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. 1 Age-adjusted to the 2000 U. S. standard population. 2 U. S. Incidence data source: 18 SEER registries. ↓↑Rate of Louisiana is significantly different from that of the U. S. Black Female

Incidence Rates of All Cancer Sites# in the Louisiana, All Races, Both Sexes, 2010 -2014 # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin.

All Cancer Sites Incidence #, 1, 2, by Region 3: Louisiana, Whites, 2010 -2014 1000 800 Rate Per 100, 000 600 [VALUE]* [VALUE]* 454. 4 [VALUE]* 451. 8 400 200 # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. 1 Age-adjusted to the 2000 U. S. standard population. 2 Data source for U. S. was the 18 SEER registries. 3 See Appendix A. * Incidence rate of regions/Louisiana is significantly different from that of U. S. . . S U LA N or th e es th w N or en C as t t l tra es t hw a So ut Ac ad ia n st he a So ut R to n Ba N ew O rle ou an s ge 0

All Cancer Sites Incidence #, 1, 2, by Region 3: Louisiana, Blacks, 2010 -2014 1000 600 [VALUE]* [VALUE]* 469. 4 [VALUE]* 459. 3 400 200 # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. 1 Age-adjusted to the 2000 U. S. standard population. 2 Data source for U. S. was the 18 SEER registries. 3 See Appendix A. * Incidence rate of regions/Louisiana is significantly different from that of U. S. . . S U LA N or th e es th w N or en C as t t l tra t es hw a So ut Ac ad ia n st he a So ut R to n Ba ew O rle ou an s ge 0 N Rate Per 100, 000 800

All Cancer Sites: Trends of Incidence Rates #, 1, 2, , Whites, 1988 -2014 700 600 Rate per 100, 000 500 400 300 200 100 LA Male LA Female US Male US Female 0 1988 1993 1998 2003 2008 Year of Diagnosis # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. 1 Age-adjusted to the 2000 U. S. standard population. 2 U. S. data source: 18 SEER registries. 2013

All Cancer Sites: Trends of Incidence Rates #, 1, 2, Blacks 1988 -2014 800 700 Rate Per 100, 000 600 500 400 300 LA Male LA Female 200 US Male US Female 100 0 1988 1993 1998 2003 2008 Year of Diagnosis # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. 1 Age-adjusted to the 2000 U. S. standard population. 2 U. S. data source: 18 SEER registries. 2013

All Cancer Sites#: Prevalence Counts* by Parish, Louisiana # Included all invasive cases and bladder in situ cases except squamous cell carcinoma of skin. * 14 -year (01/01/2000 - 01/01/2014) limited duration prevalence counts are calculated by National Cancer Institute SEER*Stat software (version 8. 3. 2).

Common Cancers with Highest Mortality Rate 1 in Louisiana, 2010 -2014 Lung & Bronchus 55. 1 24. 2 Breast (Female) Prostate (Male) 22. 5 Colon & Rectum 17. 9 Pancreas 13. 1 Liver & Bile Duct 8. 1 Leukemia 7 Ovary (Female) 6. 7 Non-Hodgkin Lymphoma 6. 6 Kidney & Renal Pelvis 5 0 1. Data source: NCI state cancer profile 10 20 30 40 50 60

All Cancer Sites: Mortality Rates 1 Louisiana vs. U. S. 2, 2010 -2014 350 LA US 18% 291. 9 Rate Per 100, 000 300 11% 250 200 247. 3 223 10% 200 178. 7 6% 150 161. 8 141. 9 100 50 0 White Male White Female Black Male 1 Age-adjusted to the 2000 U. S. standard population. 2 Mortality data source was National Center of Health Statistics (NCHS). ↓↑Rate of Louisiana is significantly different from that of the U. S. Black Female

Mortality Rates of All Cancer Sites in Louisiana, All Races, Both Sexes, 2010 -2014

All Cancer Sites: Trends of Mortality Rates 1, 2, Whites, 1988 -2014 400 Rate Per 100, 000 350 LA Male LA Female US Male US Female 300 250 200 150 100 50 0 1988 1993 1998 2003 Year of Death 1 Age-adjusted to the 2000 U. S. standard population. 2 Data source: National Center of Health Statistics (NCHS). 2008 2013

All Cancer Sites: Trends of Mortality Rates 1, 2, Blacks, 1988 -2014 600 Rate Per 100, 000 500 LA Male LA Female US Male US Female 400 300 200 100 0 1988 1993 1998 Year of Death 1 Age-adjusted to the 2000 U. S. standard population. 2 Data source: National Center of Health Statistics (NCHS). 2003 2008 2013

All Cancer Sites: Louisiana 1988 -2014: Trends of Incidence # and Mortality Rates by Gender 1000 Rate per 100, 000 800 Male Incidence (APC=-0. 4*) Female Incidence (APC=0. 4*) Male Mortality (APC = -1. 5*) Female Mortality (APC = -0. 8*) 600 400 200 0 1988 1993 1998 2003 2008 Year of Diagnosis/Death Annual average percent change (APC) were calculated using weighted least squares method. * APC significantly different from zero. #Invasive cases only. 2013

All Cancer Sites: Louisiana 1988 -2014: Trends of Incidence# and Mortality Rates by Race 1000 Rate per 100, 000 800 White Incidence (APC=0. 1) White Mortality (APC = -1. 0*) Black Incidence (APC=0. 1) Black Mortality (APC = -1. 2*) 600 400 200 0 1988 1993 1998 2003 2008 Year of Diagnosis/Death Annual average percent change (APC) were calculated using weighted least squares method. * APC significantly different from zero. # Invasive cases only. 2013

5 -year Relative Survival Rate (%) All Cancer Sites #: Louisiana 5 -Year Relative Survival by Stage 1, White Males, 2007 -2013 Percent of Cases by Stage 100% 87. 20% Unstaged 2% 80% 60% Distant 23% 58. 10% 45. 90% 40% 20% 16. 30% 0% Localized Regional Distant Unstaged Regional 20% # Included all invasive cases except squamous cell carcinoma of skin. 1 The stage distribution is based on Summary Stage 2000. Localized 55%

All Cancer Sites#: Louisiana 5 -Year Relative Survival by Stage 1, White Females, 2007 -2013 5 -year Relative Survival Rate (%) 100% 86. 60% Percent of Cases by Stage 80% Unstaged 2% 65. 70% Distant 22% 60% 47. 00% 40% 20% 18. 40% Localized 50% 0% Localized. Regional Distant Unstaged Regional 26% # Included all invasive cases except squamous cell carcinoma of skin. 1 The stage distribution is based on Summary Stage 2000.

5 -year Relative Survival Rate (%) All Cancer Sites#: Louisiana 5 -Year Relative Survival by Stage 1, Black Males, 2007 -2013 100% Percent of Cases by Stage 86. 80% Unstaged 2% 80% 60% Distant 27% 53. 70% 36. 90% 40% 20% Localized 52% 14. 40% 0% Localized Regional Distant Unstaged Regional 19% # Included all invasive cases except squamous cell carcinoma of skin. 1 The stage distribution is based on Summary Stage 2000.

All Cancer Sites#: Louisiana 5 -Year Relative Survival by Stage 1, Black Females, 2007 -2013 5 -year Relative Survival Rate (%) Percent of Cases by Stage 100% Unstaged 3% 84. 30% 80% 60% Distant 26% 59. 20% Localized 42% 37. 10% 40% 20% 17. 20% 0% Localized Regional Distant Unstaged Regional 29% # Included all invasive cases except squamous cell carcinoma of skin. 1 The stage distribution is based on Summary Stage 2000.

Appendix A. Regions of the Louisiana Tumor Registry Beginning Date of the Registry Average Annual Population, 2010 -2014 Region 1 –New Orleans 1974 21, 864 Jefferson, Orleans, St. Bernard Region 2 – Baton Rouge 1983 23, 410 Ascension, Assumption, East Baton Rouge, East Feliciana, Iberville, Livingston, Pointe Coupée, St. Helena, Tangipahoa, West Baton Rouge, West Feliciana Region 3 – Southeast Louisiana 1983 17, 036 Lafourche, Plaquemines, St. Charles, St. James, St. John, St. Tammany, Terrebonne, Washington Region 4 – Acadiana 1983 17, 032 Acadia, Evangeline, Iberia, Lafayette, St. Landry, St. Martin, St. Mary, Vermilion Region 5 – Southwest Louisiana 1983 7, 698 Allen, Beauregard, Calcasieu, Cameron, Jefferson Davis Region 6 – Central Louisiana 1988 8, 283 Avoyelles, Catahoula, Concordia, Grant, La Salle, Rapides, Vernon, Winn Region 7 – Northwest Louisiana 1988 14, 817 Bienville, Bossier, Caddo, Claiborne, De Soto, Natchitoches, Red River, Sabine, Webster Region 8 – Northeast Louisiana 1988 9, 061 Caldwell, East Carroll, Franklin, Jackson, Lincoln, Madison, Morehouse, Ouachita, Richland, Tensas, Union, West Carroll Entire State 1988 119, 201 Regional Registry Parishes Covered Source: U. S. Bureau of Census and National Cancer Institute, April 2017.

Data Sources Surveillance, Epidemiology, and End Results (SEER) Program (www. seer. cancer. gov) SEER*Stat Databases, National Cancer Institute, DCCPS, Surveillance Research Program, Surveillance Systems Branch, released April 2017, based on the November 2016 submission. For Incidence: • Incidence - SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2016 Sub (2000 -2014) <Katrina/Rita Population Adjustment> For Mortality: • mortality – All COD, Aggregated With State, Total U. S. (1969 -2014) <Katrina/Rita Population Adjustment>> For Survival: • Incidence - SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2016 Sub (1973 -2013 varying)

Data Sources • USCS: • U. S. Cancer Statistics Working Group. United States Cancer Statistics: 1999 -2014 Incidence and Mortality Web-based Report. Atlanta: U. S. Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute; 2017. Available at: www. cdc. gov/uscs. • Cancer facts & figures • American Cancer Society. Cancer Facts & Figures 2017. Atlanta: American Cancer Society; 2017.

Data Sources NCI State profiles • Incidence Data Sources: - Incidence data are provided by the National Program of Cancer Registries External Web Site Policy Cancer Surveillance System (NPCR-CSS), Centers for Disease Control and Prevention and by the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program External Web Site Policy. - Population counts for denominators are based on Census populations as modified by NCI. - Rates are calculated using SEER*Stat External Web Site Policy. • Mortality Data Sources: - Mortality data are provided by the National Vital Statistics System External Web Site Policy at the National Center for Health Statistics of the Centers for Disease Control and Prevention. - Population counts for denominators are based on Census populations as modified by NCI. . - Rates are calculated using SEER*Stat External Web Site Policy. - Trends are determined by using Joinpoint External Web Site Policy analysis of available historical data and reporting the last segment as the most recent trend.

Acknowledgements • • Hospital cancer registries (http: //louisianatumorregistry. lsuhsc. edu/) Louisiana Cancer Registrars’ Association (http: //www. lcra-usa. org/) Physicians and staff members in: • Medical records offices • Pathology laboratories • Physician offices and clinics • Hospice programs and nursing homes Regional and central offices of the Louisiana Tumor Registry (http: //louisianatumorregistry. lsuhsc. edu/regionalregistries. html) School of Public Health, LSU Health Sciences Center–New Orleans Louisiana Cancer and Lung Trust Fund Board Coroners’ offices

Sources of LTR Funding • National Cancer Institute, SEER Program • Centers for Disease Control and Prevention (CDC), National Program of Cancer Registries (NPCR) • Louisiana Health Care Services Division

Editors Yaling Li, BS Yong Yi, Ph. D, MS Lauren Maniscalco, MPH Meichin Hsieh, Ph. D, MSPH, CTR Xiaocheng Wu, MD, MPH, CTR Contributors Brent Mumphrey, BS Tina Lefante, MPH Lisa Pareti, BS, RHIT, CTR

Questions? Contact: LTR-info@lsuhsc. edu or 504/568 -5757