Diphtheria Prevention and Control Measures Katrina Kretsinger MD
- Slides: 8
Diphtheria Prevention and Control Measures Katrina Kretsinger, MD, MA LCDR, US PHS Bacterial Vaccine-Preventable Diseases Branch National Immunization Program 10/28/2020
Vaccination • Routine diphtheria vaccination – Childhood vaccination with DTa. P – Boosters with Td, starting at age 11 -12 years, every 10 years • Catch-up vaccination as indicated 10/28/2020
Travelers to Diphtheria-Endemic Regions • Pre-travel consultation – Td boosters within 10 years – Primary series 10/28/2020
Suspected Diphtheria Cases • Epidemiologic risk factors – Contacts of known cases – Travelers returning from endemic regions – Persons with incomplete vaccination • Clinical presentation 10/28/2020
Management of Patients with Suspected Diphtheria • Nasopharyngeal culture • Clinicians consult CDC re. DAT release • 770 488 -7100 • Antimicrobial therapy • Droplet precautions • Update active immunization 10/28/2020
Public Health Response to Suspected Cases • Assess risk status of suspected case • Td vaccination of HCWs and close contacts (share utensils, living quarters) – Update Td status if > 5 years – 3 -dose primary series if not previously vaccinated • Monitor close contacts for 7 days for development of symptoms • Consider culture and prophylaxis of contacts 10/28/2020
Acknowledgments Tejpratap Tiwari Marty Roper 10/28/2020
Surveillance Case Definition • Case definition: – Clinical: upper respiratory infection with sore throat, low grade fever, adherent membrane – Laboratory: isolation of C. diphtheriae – Probable case: clinical symptoms w/o epi-link or lab confirmation 10/28/2020
