25 1 Genotypic and Allelic Frequencies Are Used

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25. 1 Genotypic and Allelic Frequencies Are Used to Describe the Gene Pool Of

25. 1 Genotypic and Allelic Frequencies Are Used to Describe the Gene Pool Of a Population • Calculating genotypic frequencies • F = No. AA individuals/N • N: total no. of individuals • F: frequency of AA alleles. • Calculating allelic frequencies • Frquency of an allele = No. copies of the alleles/No. copies of alleles at the locus in a population.

25. 2 The Hardy-Winberg Law Describes the Effect of Reproduction on Genotypic and Allelic

25. 2 The Hardy-Winberg Law Describes the Effect of Reproduction on Genotypic and Allelic Frequencies • Hardy-Weinberg Law • Assumption: population is large, randomly mating, not affected by mutation, migration, or natural selection. • Prediction 1: the allelic frequencies of a population do not change. • Prediction 2: the genotypic frquencies stabilize.

Genotypic frequencies at H-W equilibrium • p+q=1 • p 2 + 2 pg +

Genotypic frequencies at H-W equilibrium • p+q=1 • p 2 + 2 pg + q 2 = 1 • P 2: homozygous dominant allele pair frequency. • Q 2 : homozygous recessive allele pair frequency. • 2 pq: heterozygous allele frequency.

Concept Check 1 What is the expected frequency of heterozygotes in a population with

Concept Check 1 What is the expected frequency of heterozygotes in a population with allelic frequency X and Y that is in H-W? a. b. c. d. X+Y XY 2 XY (X- Y)2

Concept Check 1 What is the expected frequency of heterozygotes in a population with

Concept Check 1 What is the expected frequency of heterozygotes in a population with allelic frequency X and Y that is in H-W? a. b. c. d. X+Y XY 2 XY (X- Y)2

25. 3 Nonrandom Mating Affects the Genotypic Frequencies of a Population • Positive assortative

25. 3 Nonrandom Mating Affects the Genotypic Frequencies of a Population • Positive assortative mating: • a tendency of like individuals to mate. • Negative assortative mating: • A tendency of unlike individuals to mate.

Inbreeding • Increases frequency of homozygotes in population • Rate is affected by how

Inbreeding • Increases frequency of homozygotes in population • Rate is affected by how closely related mating pairs are

Concept Check 2 What is the effect of outcrossing on a population? a. b.

Concept Check 2 What is the effect of outcrossing on a population? a. b. c. d. Allelic frequency changes in the population. More heterozygotes will be produced in the population. Fewer heterozygotes will be produced. It will reach the H-W equilibrium

Concept Check 2 What is the effect of outcrossing on a population? a. b.

Concept Check 2 What is the effect of outcrossing on a population? a. b. c. d. Allelic frequency changes in the population. More heterozygotes will be produced in the population. Fewer heterozygotes will be produced. It will reach the H-W equilibrium

25. 4 Several Evolutionary Forces Potentially Cause Changes in Allelic Frequencies • Mutation •

25. 4 Several Evolutionary Forces Potentially Cause Changes in Allelic Frequencies • Mutation • Migration • Genetic Drift • Founder effect • Genetic bottle neck • Natural selection