25 1 Genotypic and Allelic Frequencies Are Used
- Slides: 16
25. 1 Genotypic and Allelic Frequencies Are Used to Describe the Gene Pool Of a Population • Calculating genotypic frequencies • F = No. AA individuals/N • N: total no. of individuals • F: frequency of AA alleles. • Calculating allelic frequencies • Frquency of an allele = No. copies of the alleles/No. copies of alleles at the locus in a population.
25. 2 The Hardy-Winberg Law Describes the Effect of Reproduction on Genotypic and Allelic Frequencies • Hardy-Weinberg Law • Assumption: population is large, randomly mating, not affected by mutation, migration, or natural selection. • Prediction 1: the allelic frequencies of a population do not change. • Prediction 2: the genotypic frquencies stabilize.
Genotypic frequencies at H-W equilibrium • p+q=1 • p 2 + 2 pg + q 2 = 1 • P 2: homozygous dominant allele pair frequency. • Q 2 : homozygous recessive allele pair frequency. • 2 pq: heterozygous allele frequency.
Concept Check 1 What is the expected frequency of heterozygotes in a population with allelic frequency X and Y that is in H-W? a. b. c. d. X+Y XY 2 XY (X- Y)2
Concept Check 1 What is the expected frequency of heterozygotes in a population with allelic frequency X and Y that is in H-W? a. b. c. d. X+Y XY 2 XY (X- Y)2
25. 3 Nonrandom Mating Affects the Genotypic Frequencies of a Population • Positive assortative mating: • a tendency of like individuals to mate. • Negative assortative mating: • A tendency of unlike individuals to mate.
Inbreeding • Increases frequency of homozygotes in population • Rate is affected by how closely related mating pairs are
Concept Check 2 What is the effect of outcrossing on a population? a. b. c. d. Allelic frequency changes in the population. More heterozygotes will be produced in the population. Fewer heterozygotes will be produced. It will reach the H-W equilibrium
Concept Check 2 What is the effect of outcrossing on a population? a. b. c. d. Allelic frequency changes in the population. More heterozygotes will be produced in the population. Fewer heterozygotes will be produced. It will reach the H-W equilibrium
25. 4 Several Evolutionary Forces Potentially Cause Changes in Allelic Frequencies • Mutation • Migration • Genetic Drift • Founder effect • Genetic bottle neck • Natural selection
- Genotype vs allele frequency
- Lethal gene
- Mendelian slicer
- Mikael ferm
- Allelic heterogeneity
- Non-allelic homologous recombination
- Allelic heterogeneity
- Allelic heterogeneity
- Allelic exclusion
- Genetica
- Allelic exclusion
- Heterogosity
- Phenotypic ratio of dihybrid cross
- Phenotype of a pea plant
- Phenotype ratio
- Dihibrid cross
- Homozygous letters