Testicular Tumours Mr C Dawson Consultant Urologist Edith

Testicular Tumours Mr C Dawson Consultant Urologist Edith Cavell Hospital Peterborough

Incidence of Testicular tumours • 1 -2% of all tumours in men • The most common tumour in men aged 20 -35, excluding leukaemia • Incidence of approx 2 cases / year/ 100, 000 men in population • Higher incidence in caucasians • Right side > left side • Incidence is increasing

Aetiology of testicular tumours • • • [Chemical] [viral] Trauma to testicle Atrophy of testicle Cryptorchidism

Classification of Testicular tumours Primary Germ cell (97%) Seminoma Non-seminoma Embryonal carcinoma Teratoma Choriocarcinoma Yolk sac tumours Non Germ cell tumours (3%) Secondary (Metastasis) - 0. 9% of all: Prostate, bronchus, pancreas, melanoma, bladder TCC, Thyroid Ca

Classification of testicular tumours

Seminoma • 42% of all testis tumours • Tend to appear later than other tumours (mean 31 -41 yrs) • More common than NSGCT in undescended testis

Non-seminoma germ cell tumours (NSGCT) • • Embryonal carcinoma 76% Teratoma 5% Choriocarcinoma 1% Approx 25% are mixed types – commonly embryonal carcinoma and teratoma (aka “teratocarcinoma) - 64 % also contain seminoma – Embryonal carcinoma and seminoma (5%) • Yolk sac tumours - does not occur on its own in adults

NSGCT • Teratoma • Yolk-sac Tumour

Symptoms and Signs • • Swelling Fullness or heaviness in scrotum Occasionally pain Rarely - symptoms of metastatic disease – Haemoptysis – Supraclavicular mass (lymph node) – Abdominal mass • Occasionally, systemic endocrine effects, e. g. gynaecomastia