PARALAX Life Sciences Investment and Executive Consulting Group

PARALAX Life Sciences Investment and Executive Consulting Group of Companies for Innovative Implementation of Medical and Life Science Products and Services in Bulgaria

What is PLS? A private equity company; Dedicated to Life Sciences and development of new healthcare strategies; Investments from private funds in Bulgaria, Germany, Austria; € 3 500 000 invested since 2008; 23 successful companies; 200 jobs created.

Selected Portfolio of Companies Life Sciences Other related Ascendent Medical Center NM Consult Pro. Du. Ct/ Milray/ CCDRD/ Milray Moldova – clinical trials and personalized medicine projects Simbula – consulting company SGP Biodynamics – wholesaler of medical devices NM Genomix– transplantation of cells, B 2 C genetic diagnosis Pharmalex Bulgaria – vigilance of drugs, medical devices and cosmetics Institute for Medical Research – clinical and scientific services Mil. REIT – real estate holding and management company Several start-ups 3 NGO’s in public interest

Why Partners Choose Paralax LS? Existing infrastructure, including a wholesaler of medical devices and 4 companies for clinical trials in its portfolio; Excellent contacts with KOLs and stakeholders in all fields of Life Science in Bulgaria; Employees with relevant expertise in co-operation with competent authorities; A good network and extensive capacity to expand.

Main Credentials Comprehensive regulatory services; Non-disclosure & confidentiality; Long term commitment; Expertise in management of “difficult” and complex medical projects in tough environment; Excellent contacts in key EU countries.

Retail Human Genetics Offering non-invasive prenatal testing – Prenatest®, Cystic fibrosis screening test, Fra. X, Factor V Leiden, etc. ; Oncology – Maintrac®, Treatment Map®, BRCA; Ambry Genetics; Personalization of therapy – EGFR, RAS, BRAF testing; Validation tests for Trovagene and The Genomic Institute of Singapore / non-disclosable due to NDA; Partnering with Mamma. Print. *All this activities without an own genetic lab

Wholesale of Diagnostic and Life Science Solutions In Vitro Diagnostics – infectious diseases, oncology, and human genetics; Applied Testing – forensics, food safety, and veterinary medicine; Life Science Solutions – DNA and RNA extraction, PCR kits and reagents, oligonucleotides and genomic services; expression studies Lab Automation – sample disruption, nucleic acid extraction, detection (analysis), quality assessment, liquid handling, and general equipment.

Clinical Trials in Germany, Bulgaria and Moldova Existing since 1994; 10 + inspections from competent authorities – France, Spain, South Africa, Bulgaria; 150+ audits during different trials; Huge expertise in BE trials / 20+ annually/ and phase III trials; Fast and reliable process for permission of clinical trials; CRA rental might be discussed; Fast recruitment of patients in specific areas.

Outpatient Medical Center Profile in endocrinology and female health; Local independent ethics committee, inspected and audited from the Bulgarian Drug Agency; Long history of clinical trials; Existing reliable database of patients and healthy volunteers; 5 -7 Phase III trials p. a. ; Doctors with several GCP trainings and record of clinical trials; 10 BE trials p. a. in the dedicated department with 13 beds; English speaking coordinator of CT with GCP trainings.

Personalized Medical Solutions Offering complete workflow for personalized therapy in cancer and hepatitis patients to big pharma; Genetic testing is not covered by the National health Insurance Fund; RAS, EGFR, BRAF, PDL 1 testing; Patients centricity of the workflow; TAT for the entire testing up to 1 week.

Clinical and Scientific Services Scientific projects - exploratory data analysis, abstract writing, literature search services, statistical and epidemiological reports, research proposals, Integrated Summary of Efficacy (ISE) and Integrated Summary of Safety (ISS), etc. ; Validation studies – know-how in oncology and infectious diseases; IMR, along with Joint Genomic Center (JGC), Department of Medicine of the University of Padua (Italy), Hospital for Women‘s Health – “Nadezhda”, and Conofrance/CTI Biotech (France), is a founding partner of Innovation Cluster for Modern Personalization of the Transplantation of Organs, Tissues and Cells.

Additional Information http: //paralaxlife. eu/ http: //www. ascendent. bg/ http: //www. nmgenomix. com/ http: //www. simbula. eu/ http: //www. ccdrdag. com/ http: //www. milray. org/ http: //sgpbiodynamics. com/ http: //pharmalex. com/ http: //www. iqsbulgaria. com/ https: //imresearch. co/ http: //www. bapemed. org/

THANK YOU! JIVKO IVANOV Managing Director, PARALAX Life Sciences JSC mobile +359 884 572 775 e-mail jivko. ivanov@simbula. eu address 45 Bacho Kiro Str. , Sofia, Bulgaria website http: //paralaxlife. eu/