Technology Transfer transforms knowledge into money Technology driven

…. Technology Transfer transforms knowledge into money… Technology driven, human oriented Kosice May 7, 2019 Pavol Miskovsky, director

motivation Reaction of the University on recent and supposed development of the society: LOOKING FOR SOLUTIONS FOR A SIGNIFICANT QUALITATIVE CHANGE /DEVELOPMENT OF THE UPJŠ RESEARCH AND TECHNOLOGIES 4 PR is characterized by a fusion of technologies Convergence of physical, digital and biological spaces (Bio - Nano - Info) - Recombinant Technologies Breakthrough recombinant technologies are expected mainly in the following areas: • artificial intelligence • robotics • autonomous vehicles • 3 -D printing • nanotechnology • biotechnology / biomedicine INTERDISCIPLINARITY = FUSION significantly stronger connection between natural, technical and medical sciences

TIP-UPJS in the structure of the UPJŠ Innovative education Ca te ua et rad ark e g or m tiv ac e lab th in A MODERN UNIVERSITY IS BASED ON THE SYNERGY OF THREE PILLARS: "MOVING-UP TRIANGLE" RESEARCH pi res taliz ea able rch EDUCATION TECHNOLOGY TRANSFER AREA NEEDED A PROFESSIONAL DEVELOPMENT AT UPJS Functioning "eco-system" (effective penetration between pillar)

TECHNOLOGY AND INOVATION PARK OF THE UNIVERSITY OF P. J. SAFARIK IN KOSICE (TIP-UPJS) TIP-UPJŠ is a center of scientific and technological excellence at UPJS in the field of biomedicine, biotechnology, information technology and advanced materials TECHNOLOGY DRIVEN, HUMAN ORIENTED SOCIETY EQUILIBRIUM TECHNOLOGIES TIP-UPJS

technology and innovation park UPJS in Kosice (TIP-UPJS) Based on projects implementation Creating technologyinnovation centers as one of the results of projects implementation Focus - new technologies (developed into projects) Space for social sciences FREE area Experimental infrastructure (core facilities) Technology transfer CELIM MEDIPARK TECHNICOM PROMATECH Center for Interdisciplinary Biosciences (CIB) Center for Translation Medicine (CTM) Center for Informatics and Information Technologies (CIIT) Center for Progressive Materials (CPM) • Nanomedicine • Protein engineering • Aging and oxidation stress • Environment • Regenerative medicine • Personalized medicine • Biobanking • Information and knowledge systems • Cybersecurity • Communication and collaboration systems • AI • Modern functional materials: - Bioapplications - Construction - Electronics - Engineering TECHNOLOGY vs SOCIETY- sociology, psychology, law, ethics - "responsible system of society governance / regulation" Personality-based science projects (mainly reintegrants and young people from Kosice scientific institutions) - the possibility of 2 -3 year stays in TIP-UPJŠ. To the best ones will be given the opportunity to be included in the TIP structure. • Central unique experimental laboratories (core facilities) – example : central imaging facility (Euro-Bio. Imaging) • Computation cloud • Other experimental setups in specialized laboratories of TIP-UPJS start-up Pre-incubator start-up accelerator start-up incubator • SAFTRA imagine • SAFTRA 3 D mapping • DEG bioresearch spin-off companies already on the market • SAFTRA photonics • R. V. Magnetics

technology transfer– identifying problems with State aid START-UP PRE-INCUBATOR START-UP AKCELERATOR Start-up establishment, investment help from the TIP-UPJS : 20 k € Decision of the Council for Transfer about a continuation in the accelerator Education and practical training in "start-up culture" developing skills needed for business NIPOC FVS TIP practical training in start-up Theoretical Business education 1 YEAR FLUENT Support of the TIP in finding an investor, lab, space and facilities rental 2 YEAR PROBLEMS WITH STATE AID SPIN-OFF Disconnection from UPJS Cooperation Agreement (custom research, lab, space and facilities rental, etc. ) 2 YEAR DISCONNECTION FROM UPJS

goals of the TIP-UPJS MAIN GOAL: MILESTONES: 1. SHORT-TERM OBJECTIVE : CREATION OF A MODERN RESEARCH & APPLICATION CENTER ON INTERNATIONAL LEVEL The main mission of TIP-UPJŠ is to build an important European center in capitalizable research, with an effective background/support for business activities in the high-tech industry. human potential: a) Reintegration - Slovak experts from abroad b) Foreign experts – in the frame of international projects (post-doc, ERA chair. . . ) 2. MIDDLE OBJECTIVE : competitiveness in international space (science a technology) 3. LONG-TERM OBJECTIVE : contribute significantly to the creation of high-tec industries in the region and in Slovakia

particular goals of the TIP-UPJS SPECIFIC GOALS • An internationally recognized level of modern capitalizable research in a limited number of focus • High potential for technology transfer with outputs through its own start-up company • Real cooperation with high-tech industries in these areas • Membership in European Science (ERA) and Technology (ETP) networks • High potential in contributing to the growth of the regional / national economy and employment growth (through the creation of above-standard conditions for investors in the high-tech sector through the offer of results of capitalizable research)

project partners OUR PARTNERS IN DEDICATED SPECIALIZATIONS Nanomedicine ü ü ü Regenerative medicine EPFL Lausanne, ü Switzerland UZH Zurich, Switzerland Ústav ü polymérov, SAV ü ü ü ü Joint Encapsulation Consortium Juvenile Diabetes Research Foundation, USA Chicago Diabetes Project, USA University of Illinois, Chicago, USA Cell. Trans, Inc Chicago, USA Montreal University, CND MIT, USA Otsuka Pharmaceutical Factory, Inc. , JPN Kyushu University, Fukuoka, JPN Bioencapsulation Research Group, Nantes, FR Personalized medicine ü ü ü ü National Cancer Institute, USA National Institute on Aging, USA National Institute of Arthritis and Musculoskeletal and Skin Diseases, USA Rockefeller University, USA University of Iceland, Island University of Southern Denmark Hadassah Medical Center, The Hebrew University of Jerusalem, Izrael Environment ü ü ü Metawater, JPN SURFACE, Nemecko RECETOX, ČR Renishaw, GB Shimadzu (Japonsko) NEWRI (Singapur) Infrastructure ü ERA networks: § Euro-Bio. Imaging § ECRIN

RIADIACA ŠTRUKTÚRA TIP-UPJŠ Dozorná rada TIP-UPJŠ (predseda: rektor (prorektor) UPJŠ, členovia: riaditeľ, prevádzkový riaditeľ, osobnosti z vedy, priemyslu a obchodu) Vedenie a Prevádzkova administratíva TIP-UPJŠ Prevádzkový riaditeľ TIPUPJŠ (CAO) sekretari át vedúci CIB Riaditeľ TIP-UPJŠ (CEO) vedúci CTCM vedúci CIIT vedúci CPM Vedenie Prevádzkova administratíva TIP-UPJŠ Oddelenie finančného manažmentu Oddelenie projektového manažmentu Oddelenie PR manažmentu Oddelenie transferu technológií TTO RKR 20. 5. 2019 . . správa financií, fondov a investícií. . príprava a manažment projektov. . PR, diseminácia. . . . technologický transfer, marketing, bussines plán, IPR. . Rada pre transfer a inovácie TIPUPJŠ predseda: riaditeľ TIP-UPJŠ, členovia: prevádzkový riaditeľ TIPUPJŠ, vedúci CIB, CTM, CIIT, CPM, osobnosti z vedy, priemyslu a obchodu Medzinárodný poradný výbor TIP -UPJŠ predseda: riaditeľ TIP-UPJŠ, členovia: medzinárodne uznávané osobnosti z oblasti vedy a hightech priemyslu

technology transfer office (TTO) collaboration with the JRC UPJŠ TUKE UVLF mesto Košice samosprávny kraj • • • Technology Scouting IP Identification IP Generation (patentability, freedom to operate, etc. ) IP Management (valuation, evaluation) IP Licensing IP Assignment Dispute Resolution (arbitration and mediation) Spin-off Creation and Management Investor Relations Entrepreneurship

Success criteria impact measurement • • Survival rate of startups (deep-tech vs. software!) No. /growth/revenues of tenant companies No. of eobs/employees Taxes paid/collected Creation/ protection / commercialization of IP Broader social impact (young people in the country) Regeneration of local community ….

súčasná situácia TIP-UPJŠ zriadené k 4. 9. 2017: ostrý štart od 1. 1. 2018 Čo sme zvládli doteraz: ü Ustanovený prevádzkový riaditeľ TIP-UPJŠ: ing. Zuzana Svoreňová ü Menovaná dozorná rada TIP-UPJŠ – predseda prof. RNDr. Pavol Sovák, CSc. ü Zriadené jednotlivé centrá: Ø CIB – vedúci doc. Erik Sedlák, Ph. D Ø CIIT – vedúci RNDr. Erik Bruoth, Ph. D Ø CPM – vedúci prof. RNDr. Rastislav Varga, Dr. Sc. (poverený, problémy s prechodom na TIP ÚFV ) Ø CTM – doteraz nezriadené – jednania s LF UPJŠ Ø Nové priestory v MEDIPERKu ü Schválený organizačný poriadok TIP-UPJŠ (vrátane tvorby rozpočtu na UPJŠ) ü Pripravený návrh štruktúry pracovných pozícií TIP-UPJŠ (na najbližšie zasadnutie senátu UPJŠ)

TIP-UPJS localization – recent & future situation Centers distributed in various university buildings Project for new TIP-UPJS & new university campus

timetable 4 years vision Public-private partnerships (PPPs) Typical Advantages: - Transfer risk to (share with) private sector - Expertise and know-how of private sector - Increased efficiency and quality - Make R&I policy more responsive to the nature of innovation Developments: - Rise in PPPs in the STI area that are strategic, long-term and large-scale (OECD, 2016) - Reduce uncertainties in R&I by allowing for long-lasting and large-scale commitments

Thank you for your attention

FINANCOVANIE TIP-UPJŠ Projekty ŠF Do roku 2022 by projekty ŠF mali byť hlavným zdrojom financovania budovania infraštruktúry TIP-UPJŠ ako i podpory aktivít v oblasti transferu technológií Štátny rozpočet Dotačné zdroje MŠ SR vyjadrené cez ozpočet UPJŠ pri zachovaní pravidiel delenia rozpočtu na UPJŠ na základe výkonov Zahraničné Získanie zahraničných a domácich projektov je nevyhnutnou a domáce vedecké podmienkou existencie vedeckých tímov v TIP-UPJŠ projekty Zahraničné O tieto zdroje sa bude TIP-UPJŠ uchádzať cez svoje start-up firmy a a domáce projekty spolupráce s high-tech priemyslom transferu technológií Zdroje z hospodárskej činnosti Tieto zdroje budú generované z hospodárskej činnosti TIP-UPJŠ cez výrobné aktivity vytvorených start-up firiem Zdroje od Vstup investorov do malých start-up spoločností Konečným cieľom v oblasti financovania je tvorba zisku pre TIP-UPJŠ ako i pre UPJŠ investorov (angel investor. . ) Patenty a licencie SP 30. 1. 2018 Predaj patentov a licencií 18

ČASOVÝ PLÁN PRÍPRAVY PROJEKTU TIP-UPJŠ Pracovná etapa Odhadovaný čas realizácie Schválenie projektového zámeru – rozšírené vedenie UPJŠ 3. 4. 2017 Zostavenie pracovného tímu projektu TIP-UPJŠ a poverenia jednotlivých členov rektorom UPJŠ ~ 15. 4. 2017 Príprava organizačného poriadku TIP-UPJŠ ~ 30. 5. 2017 Schválenie projektu TIP-UPJŠ senátom UPJŠ ~ jún 2017 Začiatok projektu TIP-UPJŠ ~ september 2017 Príprava detailného projektu TIP-UPJŠ ~ december-január 2017 -18 Predloženie projektu TIP-UPJŠ vláde SR ~ február-marec 2018 SP 30. 1. 2018 19 Ukončené splnené splnené