GLYCOGEN STRUCTURE GLYCOGEN STRUCTURE 4 6 5 2

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GLYCOGEN STRUCTURE

GLYCOGEN STRUCTURE

GLYCOGEN STRUCTURE 4 6 5 2 3 1 α (1→ 6) glycosidic bond 4

GLYCOGEN STRUCTURE 4 6 5 2 3 1 α (1→ 6) glycosidic bond 4 6 5 3 2 1 4 6 5 3 α (1→ 4) glycosidic bond 2 1

GLYCOGEN BREAKDOWN • The granules: these are especially prominent in the cells that make

GLYCOGEN BREAKDOWN • The granules: these are especially prominent in the cells that make the greatest use of glycogen. -muscle -liver • glycogen granules also contain the enzymes that catalyze glycogen synthesis and degradation as well as many of the proteins that regulate these processes. - Glycogen phosphorylase - Glycogen debranching enzyme - Phosphoglucomutase

GLYCOGEN SYNTHESIS Glycogen Branching enzyme UDP Glycogen synthase Debranching enzyme Pi UDP-glucose PPi Glycogen

GLYCOGEN SYNTHESIS Glycogen Branching enzyme UDP Glycogen synthase Debranching enzyme Pi UDP-glucose PPi Glycogen phosphorylase Inorganic pyrophosphatase 2 Pi UDP-glucose pyrophosphorylase Glucose-1 -phosphate UTP Phosphoglucomutase Glucose-6 -phosphate Opposing pathways of glycogen synthesis and degradation. The exergonic process of glycogen breakdown is reversed by a process that uses UTP to generate a UDP-glucose intermediate.

실험 방법 -시약 및 기자재 : 얼린 (소)간, 약수저, centrifuge tube(50 ml), pestle, funnel,

실험 방법 -시약 및 기자재 : 얼린 (소)간, 약수저, centrifuge tube(50 ml), pestle, funnel, 20% TCA(Tricholoroacetic acid), Et. OH, filter paper

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