Enquiry Specific Search strategies and the Medicines Learning

Enquiry Specific Search strategies and the Medicines Learning Portal Tutorials NMSF – CPD Centre – Sudan Nov 2017 Ammar Abbas Medicines Information / Medicines Management Pharmacist Pharmacy Department Countess of Chester Hospital (COCH) NHS Foundation Trust November 2017

Objectives To become familiar with: Basic framework for handling Medicines Information (MI) enquiries UKMi Free and purchasable resources lists Enquiry specific reference sources Enquiry Answering Tutorials using the Medicines Learning Portal

Medicines Learning Portal www. medicineslearningportal. org

Administration of medicines specific reference sources Drug Administration via Enteral Feeding Tubes (via medicinescomplete) Handbook on Injectable Drugs (via medicinescomplete) IV Drugs guide (via medicinescomplete)

Adverse Drug Reactions specific reference sources Meyler’s Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions CHM—Commission on Human Medicines CHM/MHRA www. mhra. gov. uk/Committees/Medicinesadvisorybodies/Commissio non. Human. Medicines/index. htm. Drug Analysis Prints (DAPs) for Yellow Card data MHRA Interactive Drug Analysis Prints accessible via: https: //yellowcard. mhra. gov. uk/idap Note, old format still accessible from: http: //www. mhra. gov. uk/drug-analysis-prints-az/index. htm INCHEM TOXNET International Programme on Chemical Safety www. inchem. org. US National Library Medicine http: //toxnet. nlm. nih. gov/. Toxicology information including pregnancy related toxicity information. Also links to Lact. Med (see below) for drugs in lactation information. Toxicology information on chemicals and drugs.

Drug Interactions additional references Stockleys Drug Interactions PLUS HIV Drug Interactions (QT prolongation) The University of Liverpool US education organisation AZCERT Medscape drug interaction checker Medscape www. medscape. com/druginfo/druginterchecker Drugs. com interactions checker Cerner Multum Registration required. http: //www. drugs. com/drug_interactions. html Hepatitis drug interactions Credible. Meds Transformer website (Cytochrome P 450 database) (renamed Credible. Meds in 2014) Institute for Physiology; Structural Bioinformatics Group, Berlin www. hiv-druginteractions. org www. hep-druginteractions. org https: //www. crediblemeds. org/ List drugs that prolong the QT Interval and/or induce Torsades de Pointes by risk category. Registration required. To be used only after other approved sources have been used. Useful for information not readily available in UK sources. http: //bioinformatics. charite. de/transformer/ Not to be used as a first-line resource. Clinical significance of the interactions is not identified.

Injection Compatability specific references Handbook of Injectable Drugs IV Drugs Guide

Drugs in Pregnancy specific references Briggs – Drugs in Pregnancy & Lactation TOXBASE BUMPS: www. medicinesinpregnancy. org

Drugs in Lactation specific references Briggs: Drugs in Pregnancy & Lactation (available via medicinescomplete) Lact. Med US National Library of Medicine http: //toxnet. nlm. nih. gov/cgi-bin/sis/htmlgen? LACT. UKMi Drugs in Lactation database UKMi www. sps. nhs. uk Trent and West Midlands Regional Centres Also check information held in Therapeutic Group Summary link.

Drugs in Renal Disease specific references RENAL DRUG HANDBOOK / DATABASE www. renaldrugdatabase. com

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