VACS Pulmonary Critical Care Core Kristina Crothers MD

VACS Pulmonary & Critical Care Core Kristina Crothers, MD Co-Director Kathleen Akgün, MD, MS Co-Director Members: A Butt, ST Brown, D Fiellin, M Fine, CL Gibert, M Freiberg, M Goetz, C Graber, AC Justice, L Huang, J Kim, K Mc. Ginnis, M Pisani, D Rimland, MC Rodriguez-Barradas, S Shahrir, M Skanderson, G Soo Hoo, H Tindle, C Wongtrakool VACS data used for: NCRR 1 KL 2 RR 024138, NHLBI R 01 HL 090342, NHLBI RC 1 HL 100347, NCI R 01 CA 173754*, NCI R 01 CA 173754 -03 S 1* (to KC); VA VISN 1 Early CDA, Chest Foundation Award, Yale Cancer Center* (to KA) * Current

Recent VACS Pulmonary & Critical Care Core Highlights (2015 -2016) Peer Reviewed Publications • Triplette M et al. A low peripheral blood CD 4/CD 8 ratio is associated with pulmonary emphysema in HIV. PLOS ONE (in press). • Triplette M, et al. The differential impact of emphysema on respiratory symptoms and six-minute walk distance in HIV infection. JAIDS 2016 • Crothers K et al. Widespread activation of immunity and pro-inflammatory programs in peripheral blood leukocytes of HIVinfected patients with impaired lung gas exchange. Physiol Rep. 2016 • Akgün KM et al. Association of chronic obstructive pulmonary disease with frailty measurements in HIV-infected and uninfected Veterans. AIDS. 2016 • Depp TB et al. Risk factors associated with acute exacerbation of chronic obstructive pulmonary disease in HIV-infected and uninfected patients. AIDS. 2016 • Shahrir S et al. Contemplation of smoking cessation and quit attempts in human immunodeficiency virus-infected and uninfected veterans. Subst Abus. 2016 • Attia EF et al. Association of COPD With Risk for Pulmonary Infections Requiring Hospitalization in HIV-Infected Veterans. JAIDS. 2015 • Barakat LA et al. Comparing clinical outcomes in HIV-infected and uninfected older men hospitalized with community-acquired pneumonia. HIV Med. 2015 • Kunisaki KM et al. Prevalence and correlates of obstructive sleep apnoea among patients with and without HIV infection. HIV Med. 2015 Consortium Collaborations: Lung HIV and the Lung HIV Microbiome Project (LHMP) • Drummond MB et al. Factors associated with abnormal spirometry among HIV-infected individuals. AIDS. 2015 • Leader JK et al. Risk Factors Associated With Quantitative Evidence of Lung Emphysema and Fibrosis in an HIV-Infected Cohort. JAIDS. 2016 • Beck JM et al. Lung HIV Microbiome Project. Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIVuninfected Individuals. AJRCCM. 2015 Conference Presentations: ATS 2015, 2016; CROI 2015, 2016; IDSA 2015 New Grants: Yale Cancer Center Pilot Grant “COPD / Lung Cancer in HIV” (Akgün)