API RP 754 Rev 3 July 15 2020

API RP 754 Rev. 3 July 15, 2020 GHS Statement Overlay Sub-Committee

GHS Statement Overlay Sub-Committee Eric Atkins (Olin) John Grabowski (Citgo) Marty Martin (Dow Chemical) Jim Muoio (Celanese – Representing American Chemistry Council) Bill Ralph (BP) Eric Freiburger (Linde) – Ad Hoc

Changes in Table from June Meeting H 260/261 – Substances and mixtures which, in contact with water, emit flammable gases (cat 1 & cat 2, 3) Removed by sub-committee H 221 – Flammable gas, Flammable gases (chp 2. 2) (cat 1 B, 2) Placed in TRC-5 with H 220 – Flammable gas, Flammable gases (cat 1 A) H 227 Combustible liquid, Flammable liquids (chp 2. 6)(cat 4) [**Released at or above flashpoint and no upper flash point**] [No GHS designation] Liquids with Flash Point > 93 °C (200 °F) released at a temperature at or above Flash Point Placed in TRC-7; to clarify “no Upper Flashpoint” comment H 270 – May cause or intensify fire; oxidizer Oxidizing gases (chp 2. 4) (cat 1) Kept under UNDG Class 2, Division 2. 2 in TRC-7 rather than place in Other Packing Group III per suggestion in last main committee meeting [No GHS designation] Asphyxiant gases Included statement under H 270 statement above

Hazard Class Comparison (Old vs New-Draft) Threshold Release Category TRC-1 Existing RP 754 Material Hazard Classification New RP 754 GHS Material Hazard Classification TIH Zone A Materials H 330 Fatal if inhaled, Acute toxicity, inhalation (chp 3. 1) cat (1) TIH Zone B Materials H 330 Fatal if inhaled, Acute toxicity, inhalation (chp 3. 1) cat (2) TRC-2 H 310 Fatal in contact with skin, Acute toxicity, dermal (chp 3. 1) cat (1) TIH Zone C Materials H 331 Fatal if inhaled, Acute toxicity, inhalation (chp 3. 1) cat (3) TRC-3 H 310 Fatal in contact with skin, Acute toxicity, dermal (chp 3. 1) cat (2) TIH Zone D Materials H 332 Fatal if inhaled, Acute toxicity, inhalation (chp 3. 1) cat (4) TRC-4 H 311 Fatal in contact with skin, Acute toxicity, dermal (chp 3. 1) cat (3)

Hazard Class Comparison (Old vs New-Draft) Threshold Release Category Existing RP 754 Material Hazard Classification New RP 754 GHS Material Hazard Classification H 220 Extremely flammable gas, Flammable gases (chp 2. 2) (cat 1 A) Flammable Gases H 221 Flammable gas, Flammable gases (chp 2. 2) (cat 1 B, 2) Liquids with Normal Boiling Point £ 35 °C (95 °F) and Flash Point < 23 °C (73 °F) H 224 Extremely flammable liquid and vapor, Flammable liquids (chp 2. 6) (cat 1) H 228 Flammable solid, Flammable solids (chp 2. 7) (cat 1, 2) H 230 May react explosively even in the absence of air, Flammable gases (chp 2. 2) (cat 1 A, A) TRC-5 Other Packing Group I Materials (excluding acids/bases) H 231 May react explosively even in the absence of air at elevated pressure and/or temperature, Flammable gases (chp 2. 2) (cat 1 A, B) H 232 May ignite spontaneously if exposed to air, Flammable gases (chp 2. 2) 1 A, (cat 1 A pyrophoric gas) H 250 Catches fire spontaneously if exposed to air, Pyrophoric liquids and Pyrophoric solids (chp 2. 9 & 2. 10) (cat 1) H 312 Harmful in contact with skin, Acute toxicity, dermal (chp 3. 1) (cat 4) Liquids with Normal Boiling Point > 35 °C (95 °F) and Flash Point < 23 °C (73°F) H 225 Highly flammable liquid and vapor, Flammable liquids (chp 2. 6) (cat 2) H 240 Heating may cause an explosion, Self-reactive substances and mixtures and Organic peroxides (chp 2. 8 & 2. 15) (type A) TRC-6 Other Packing Group II Materials (excluding acids/bases) H 241 Heating may cause a fire or explosion, Self-reactive substances and mixtures and Organic peroxides (chp 2. 8 & 2. 15) (type B) H 242 Heating may cause a fire, Self-reactive substances and mixtures and Organic peroxides (chp 2. 8 & 2. 15) (type C-F) H 271 May cause fire or explosion; strong oxidizer, Oxidizing liquids and Oxidizing solids (chp 2. 13 & 2. 14) (cat 1)

Hazard Class Comparison (Old vs New-Draft) Threshold Release Category Existing RP 754 Material Hazard Classification New RP 754 GHS Material Hazard Classification Liquids with Flash Point ³ 23 °C (73 °F) and £ 60 °C (140 H 226 Flammable liquid and vapor, Flammable liquids (chp 2. 6) (cat 3) °F) Liquids with Flash Point > 60 °C (140 °F) released at a temperature at or above Flash Point TRC-7 strong acids/bases (see definition) UNDG Class 2, Division 2. 2 (non-flammable, non-toxic gases) excluding air H 227 Combustible liquid, Flammable liquids (chp 2. 6) 4 (cat 4) [**Released at or above flashpoint**] [No GHS designation] Liquids with Flash Point > 93 °C (200 °F) released at a temperature at or above Flash Point H 314 Causes severe skin burns, Skin corrosion/irritation (chp 3. 2) (cat 1, 1 A) H 270 May cause or intensify fire; oxidizer Oxidizing gases (chp 2. 4) (cat 1) [No GHS designation] Asphyxiant gases H 272 May intensify fire; oxidizer, Oxidizing liquids and Oxidizing solids (chp 2. 13 & 2. 14) (cat 2, 3) Other Packing Group III Materials H 318 Causes serious (irreversible) eye damage, Serious eye damage/eye irritation (chp 3. 3) (cat 1) TRC-8 Liquids with Flash Point > 60 °C (140 °F) and £ 93 °C (200 °F) released at a temperature below Flash Point H 227 Combustible liquid, Flammable liquids (chp 2. 6) 4 (cat 4) [**Released below flashpoint**] Moderate acids/bases (see definition) H 314 Causes severe skin burns, Skin corrosion/irritation, (chp 3. 2) (cat 1 B) H 319 Causes serious eye (reversible) irritation, Serious eye damage/eye irritation (chp 3. 3) (cat 2/2 A) H 370 Causes damage to organs, Specific target organ toxicity, single exposure (chp 3. 8) (cat 1)

Hazard Class Comparison (Old vs New-Draft) • Information below may be added to the footnote of the Table. Classes have been limited to acute events and events that have relevance to Process Safety: Not included: Explosives (2. 1), Aerosols (2. 3), Gases under Pressure (2. 5), Self Heating Substance (2. 11), Substances and mixtures which, in contact with water, emit flammable gases (chapter 2. 12), Corrosive to Metals (2. 16), Oral Acute Toxicity (3. 1), Respiratory and Skin Sensitization (3. 4), Germ Cell Mutagenicity (3. 5), Carcinogenicity (3. 6), Reproductive Toxicity (3. 7), Specific Target Organ Toxicity - repeated exposure (3. 9), Aspiration hazard (3. 10), Hazardous to the Aquatic Environment (4. 1), and Hazardous to the Ozone Layer (4. 2) *Not all GHS classifications align with UNDG TIH classes. For Acute toxicity, the Hazard Category must also be known; the Hazard Statement does not distinguish between Category 1 & 2. This is also the case for H 314 for which only category 1 A is considered for Tier 1 TQs. Hazard Statements and Categories from GLOBALLY HARMONIZED SYSTEM OF CLASSIFICATION AND LABELLING OF CHEMICALS (GHS) Seventh revised edition, see Annex C for GHS chapters related to Hazard Statements and Categories.

Next Steps Finalize hazard categorization • H 318/H 319 - Causes serious (irreversible) eye damage, Serious eye damage/eye irritation (chp 3. 3) (cat 1 & 2/2 A) [Similar to Strong Acid/Base & Moderate Acid/Base, respectively] Final decision will be based on where Acid/Base determination is made. • Further evaluate location in table for Acute Toxic Dermal exposures. • What about Combustible Dusts? • What other Packing Group designations need to be included? Update table(s) with feedback from other teams • Strong, moderate, and weak acids/bases; Do these remain as TRC-7 (strong) and TRC-8 (moderate)? • Indoor/Outdoor affects of non-volatile, non-flammable, non-toxic chemicals. Do these TQs need to be adjusted? If so, need to determine how to represent in the Table; maybe add comment. If approved, update API RP 754 document where TQ table changes modifies examples in Annexes.

GHS Statement Overlay Historical Comparison Eric Atkins (Olin) Kevin Hersey (Corteva Agriscience) Jim Muoio (Celanese) Bill Ralph (BP) Rodney Reibold (Marathon Petroleum)

Other Discussion: Q&A