What is smallpox Smallpox is a serious contagious

What is smallpox • Smallpox is a serious, contagious and sometimes fatal disease. • There is no specific treatment for smallpox, and the only prevention is vaccination. • The name smallpox is derived from the latin word “spotted” and refers to the raised bumps that appear on the face and body of an infected person.

Edward Jenner and Small pox • Edward Jenner was an English country doctor who pioneered vaccination. Jenner's discovery in 1796 that inoculation with cowpox gave immunity to smallpox, was an immense medical breakthrough and has saved countless lives.

How did he discover vaccination? • Jenner worked in a rural community and most of his patients were farmers or worked on farms with cattle. • In the 18 th century smallpox was a very common disease and was a major cause of death.

• The main treatment was brought to England in 1721 from Turkey by Lady Mary Wortly Montague. • This method involved inoculating healthy people with substances from the pustules of those who had a mild case of the disease, but this often had fatal results.

Cowpox • In 1788 an epidemic of smallpox hit Gloucestershire and during this outbreak Jenner observed that those of his patients who worked with cattle and had come in contact with the much milder disease called cowpox never came down with smallpox. • Jenner needed a way of showing that his theory actually worked.

• Jenner was given the opportunity on the 14 May 1796, when a young milkmaid called Sarah Nelmes came to see him with sores on her hands like blisters. Jenner identified that she had caught cowpox from the cows she handled each day.

• He carefully extracted some liquid from her sores and then took some liquid from the sores of a patient with mild smallpox. • Jenner believed that if he could inject someone with cowpox, the germs from the cowpox would make the body able to defend itself against the dangerous smallpox germs which he would inject later.

• Jenner approached a local farmer called Phipps and asked him if he could inoculate his son James against smallpox. He explained to the farmer that if his theory was correct, James would never contract smallpox. Surprisingly, the farmer agreed.

• Jenner made two small cuts on James's left arm. He then poured the liquid from Sarah's cowpox sores into the open wounds which he bandaged. • James went down with cowpox but was not very ill. Six weeks later when James had recovered, Jenner vaccinated him again, this time with the smallpox virus

• This was an extremely dangerous experiment. If James lived Jenner would have found a way of preventing smallpox. If James developed smallpox and died he would be a murderer. • To Jenner's relief James did not catch smallpox. His experiment had worked.

• Jenner called his idea " vaccination" from the word vaccinia which is latin for cowpox. • Jenner found a great deal of scepticism to his ideas and was subject to much ridicule. A cartoon was drawn, showing cows coming out of various parts of people's bodies after they had been vaccinated with cowpox.

• However, Jenner persevered and eventually, doctors found that vaccination did work and by 1800 most were using it.

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