VIRUS DNA FIDI NUR AINI E P D

VIRUS DNA FIDI NUR AINI E. P. D. FAKULTAS KEDOKTERAN HEWAN UNIVERSITAS BRAWIJAYA 2020

ICOSAHEDRAL vs HELIKS

� � The universal system of viral taxonomy is set at the levels of order, family, subfamily, genus, and species. The names of orders end with the suffix-virales, families with the suffix-viridae, subfamilies with the suffix-virinae, and genera with the suffixvirus. Lower levels, such as subspecies, strains, and variants

FAMILY HERPESVIRIDAE

� � Subfamily: Alphaherpesvirinae Genus: Simplexvirus (human herpesvirus 1 herpes simplex virus 1) Genus: Varicellovirus (human herpesvirus 3 -varicella-zoster virus) Genus: Unnamed (Marek's disease-like viruses) (Marek's disease virus) Genus: Unnamed (infectious laryngotracheitis like viruses) (infectious laryngotracheitis virus) Subfamily: Betaherpesvirinae Genus: Cytomegalovirus (human herpesvirus 5~human cytomegalovirus)

� � Genus: Muromegalovirus (mouse cytomegalovirus 1) Genus: Roseolovirus (human herpesvirus 6) Subfamily: Gammaherpesvirinae Genus: Lymphocryptovirus (human herpesvirus 4 m. Epstein-Barr virus) Genus: Rhadinovirus (ateline herpesvirus 2) Subfamily: Unnamed (channel catfish herpesviruslike viruses) (ictalurid herpesvirus 1) Genus: Unnamed (channel catfish-like herpesviruses) (ictalurid herpesvirus 1)

PATOGEN

PATOGEN IN ANIMAL � ILT dan Marek Disease

FAMILY HEPADNAVIRIDAE � � � Genus: Orthohepadnavirus (hepatitis B virus) virus serupa hepatitis B mamalia Genus: Avihepadnavirus (duck hepatitis B virus) virus serupa hepatitis B unggas Characteristics: Hepadnavirus (hepar, liver; dna, sigla for DNA) virions are spherical, 42 nm in diameter, and consist of a 27 -nm icosahedral core within a closely adherent outer capsid that contains cellular lipids, glycoproteins, and a virus-specific surface antigen (HBs. Ag). The genome consists of a single molecule of circular partially double-stranded, partially single-stranded

� Hepadnaviruses replicate in the nucleus of hepatocytes and cause hepatitis, which may progress to chronic disease, cirrhosis, and primary hepatocellular carcinoma

FAMILY PAPOVIRIDAE � Genus: Polyomavirus (murine polyomavirus) Genus: Papillomavirus (cottontail rabbit papillomavirus) � Characteristics: Papovavirus [sigla, from � � papilloma, polyoma, vacuolating agent (early name for SV 40)] virions are nonenveloped, spherical in outline, with icosahedral symmetry. Virions are 45 (genus Polyomavirus) and 55 (genus Papillomavirus/kutil) nm in diameter. The genome consists of a single molecule of circular double-stranded DNA,

FAMILY ADENOVIRIDAE � � � Genus: Mastadenovirus (human adenovirus 2) Genus: Aviadenovirus (fowl adenovirus 1) Genus : Atadenovirus (ovine adenovirus 287) Characteristics: Adenovirus (adenos, gland) virions are nonenveloped, hexagonal in outline, with icosahedral symmetry, 80 -100 nm in diameter. The genome consists of a single linear molecule of double-strande DNA, 36 to 44 kbp in size. Viruses replicate in the nucleus

FAMILY PARVOVIRIDAE � � Subfamily: Parvovirinae Genus: Parvovirus (minute virus of mice) Genus: Erythrovirus (human parvovirus B 19) Genus: Dependovirus (adeno-associated virus 2) Characteristics" Parvovirus (parvus, small) virions are nonenveloped, spherical in outline, with icosahedral symmetry, 25 nm in diameter. The genome consists of a single molecule of linear single-stranded DNA, 5 kb in size.

PATOGEN IN ANIMAL � Pathogens: Genus Parvovirus: feline panleukopenia virus, canine parvovirus 1, 2 a, and 2 b, mink enteritis virus, Aleutian mink disease virus, bovine parvovirus goose parvovirus, porcine parvovirus

FAMILY POXVIRIDAE � � Subfamily: Chordopoxvirinae Genus: Orthopoxvirus (vaccinia virus 2) Genus: Capripoxvirus (sheeppox virus) Genus: Leporipoxvirus (myxoma virus) Genus: Suipoxvirus (swinepox virus) Genus: Molluscipoxvirus (molluscum contagiosumvirus) Genus: Yatapoxvirus (yabapox and tanapox viruses) Genus: Avipoxvirus (fowlpox virus) Genus: Parapoxvirus (orf virus) Subfamily: Entomopoxvirinae Three genera: Entomopoxvirus A, B, and C (entomopoxviruses. A, B, and C)

� Characteristics: Poxviruses (poc, pocc, pustule) virions are brick shaped and complex in structure, measuring about 250 x 200 nm in size (except or the genus Parapoxvirus where virions are ovoid and 260 x 160 nm in size). The genome consists a single linear molecule of doublestranded DNA,

FAMILY ASFARVIRIDAE � Genus: Asfivirus (African swine fever virus) Characteristics: (the family name Asfarviridae is derived from African Swine Fever And Related viruses; the genus name Asfivirus is derived from African Swine Fever) virions are enveloped, 175 -2'15 nm in size and contain a complex icosahedral capsid