Viro Lab A Virtual Laboratory for Infectious Diseases

Viro. Lab “A Virtual Laboratory for Infectious Diseases“ EU project nummer: IST-027446

Project Description • Funded by European Commission within the 6 th Framework Programme for Research and Technological Development • Project in the area of integrated biomedical information for better health • 12 partners from 8 different European countries • Develop a “Virtual Laboratory” for researchers and medical doctors that facilitates medical knowledge discovery and decision support for HIV drug resistance

The AIDS Pandemic Over 40 Mio. people are living with HIV/AIDS… frightening!!! Extracted from the HIV Medicine 2006 Flyer: http: //www. hivmedicine. com

The complex interplay in HIV

A Virtual Laboratory for Medical Doctors Usage of a rule-based decision support system to preview results and drug rankings Steps: 1. Select rule set and enter mutation 2. Submit for analysis 3. Review results: 4. Drugs which best fit the mutation

A Virtual Laboratory for Researchers Definition and processing of new experiments and simulations starting from predefined templates Steps: 1. Start the predefined experiment and view its description 2. Obtain nucleotide sequence from patient database 3. Align the sequence to get a list of mutations 4. Detect HIV subtype 5. Retrieve drug ranking information

The Team

Where to find more information? http: //www. hlrs. de http: //www. virolab. org http: //ec. europa. eu/ information_society/ activities/health/