Uppsala Longitudinal Study of Adult Men ULSAM Age

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Uppsala Longitudinal Study of Adult Men (ULSAM) Age 50 1970 - 1973 N =

Uppsala Longitudinal Study of Adult Men (ULSAM) Age 50 1970 - 1973 N = 2322 Age 60 Age 77 Age 88 1980 - 1985 1991 - 1995 1997 - 2001 2008 - 2009 N = 1860 N = 1221 N = 839 N = 354 Age 82 2003 - 2005 N = 530 2011 -02 -15

Participation 2011 -02 -15

Participation 2011 -02 -15

Causes of death By October 2010, 576 participants still were alive 1746 participants have

Causes of death By October 2010, 576 participants still were alive 1746 participants have dead 2011 -02 -15

Hospital visits 74 individuals have never been at the hospital 46% off them are

Hospital visits 74 individuals have never been at the hospital 46% off them are still alive 26% died over age of 65 From remaining 2248 participants only 24% are still alive They all together have visited hospital more than 23 000 times and have spent there over 200 000 days 2011 -02 -15

Use of hospital time 1970 -2009 Total 218 847 days 2011 -02 -15

Use of hospital time 1970 -2009 Total 218 847 days 2011 -02 -15

Measurements 2011 -02 -15

Measurements 2011 -02 -15

Genetic Analyses First genetic study published in 1997 Over 4000 individual SNPs genotyped 2003

Genetic Analyses First genetic study published in 1997 Over 4000 individual SNPs genotyped 2003 - 2010 In 2010 1221 individuals were genotyped for ~180 000 SNPs using Metabo. Chip In 2010 110 individuals were genotyped using Illumina 1 M chip 2011 -02 -15

Research activity At least 50 researchers have been working with ULSAM data under last

Research activity At least 50 researchers have been working with ULSAM data under last three years Over 150 research proposals have been approved by ICTUS group from 2002 At least 220 articles have been published from ULSAM initiation in 1970 27 doctoral theses have been defended 2011 -02 -15

Articles and theses based on ULSAM cohort 2011 -02 -15

Articles and theses based on ULSAM cohort 2011 -02 -15