UNCChapel Hill and the NIH Roadmap NIH ROADMAP
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UNC-Chapel Hill and the NIH Roadmap NIH ROADMAP Tony G. Waldrop Vice Chancellor Research and Economic Development
NIH’s Roadmap Vision • Est. 2% of total NIH budget • Primary funding source: “tax” on NIH institutes • • • Emphasis: Attacking difficult problems Interdisciplinary collaboration Translation to clinic Computation/informatics • Allied projects will make Roadmap much larger than its core funding Dr. Elias Zerhouni
Themes New Pathways to Discovery • Building Blocks, Pathways, and Networks • Molecular Libraries and Imaging • Structural Biology • Bioinformatics and Computational Biology • Nanomedicine Research Teams of the Future • High-Risk Research • Interdisciplinary Research • Public Private Partnerships Re-engineering the Clinical Research Enterprise Dorsal root ganglia neurons (Annette Markus) • Clinical Research
Roadmap Planning at UNC • September, 2003: Dr. Zerhouni announces the Roadmap • January, 2004: 12 -member Carolina Roadmap Task Force is convened • March, 2004: Task Force report recommends: – Create a campus-wide organization for Roadmap projects – Demonstrate administrative support – Appoint a Roadmap chair – Provide staff and resources
UNC’s Response • NIH Roadmap Executive Committee • Chair: Rudy Juliano, Professor of Pharmacology • Executive Committee members: – Kim Brouwer, Chair Pharmacotherapy, Pharmacy – Barbara Entwisle, Director, Carolina Population Center and Professor of Sociology – Michael Fried, Professor of Medicine and Director, Hepatology Division of Gastroenterology and Hepatology – Daniel Reed, Vice Chancellor for Information Technology and Director, Institute for Renaissance Computing – Rich Superfine, Professor of Physics – David Savitz, Chair of Epidemiology
Campus Support • Roadmap Committee will steer efforts to – Build research teams and partnerships at UNC – Liaise with NIH on Roadmap – Highlight interdisciplinary research (‘workshops’) – Facilitate development of proposals – A new staff position (Karen Stone) Freeze-dried, rehydrated platelets in a canine carotid artery. (Tom Fishcher) • Seed funding from VC for proposal development • Additional support from – Offices within Research and Economic Development – College of Arts and Sciences – Schools of Medicine, Dentistry, Public Health
Action • The first round of Roadmap P 20 RFAs yields multiple UNC proposals • REC meets with multiple Departments/Centers • VC’s “Workshops In Interdisciplinary Research” • Emerging Initiatives • • Fluorescent video microscopy images of cell mitosis (Ted Salmon) • • • Metabolomics— Steve Zeisel, others Stem Cells & Transplantation—Jon Serody, others Peridontal Disease—Steve Offenbacher, others Biomedical Research Imaging Center—Etta Pisano, others Pathways & Networks—Klaus Hahn others Child abuse & physiological changes- Jonathan Kotch, others Other projects? ?
SUCCESSES Roadmap Planning Grant or other Awards PI 1. 2. 3. 4. 5. 5. 6. Theme B. Popkin R. Rindfuss B. Sartor D. Reed/ T. Magnuson G. Johnson H. Guess Department/Center Obesity Population Center Land Use & Health Population Center Imaging Inflammation Medicine Exploratory Genetics Computer Sci/ Genetics Nanomedicine Pharmacology Patient Outcomes Public Health
WHAT NEXT? 1. LOOKING FOR A FEW 2. GOOD MEN/WOMEN 3. 2. DARE TO DREAM BIG DREAMS
Help the Roadmap at UNC 1. Consider leading a Roadmap or Roadmap-Like proposal. 2. Let us know about it!! 3. 2. Help us to ‘penetrate’ the NIH. Are you on NIH Council? 4. Study Section? Advisory Group? Let us know about it!!
