Tuberculosis ORAL TUBERCULOSIS a chronic infectious disease caused

Tuberculosis

ORAL TUBERCULOSIS a chronic infectious disease caused by……… Mycobacterium tuberculosis. Worldwide, more than 2 billion people are infected with 9 million new cases and 3 million deaths per year Most infections are the result of direct person-to-person spread through airborne droplets from a patient with active disease Primary tuberculosis…… occurs in previously unexposed peopleand almost always involves the lungs. a nonspecific, chronic inflammatory reaction a localized, fibrocalcified nodule at the initial site of involvement. Primary tuberculosis ……. usually asymptomatic. Occasionally, fever and pleural effusion

Only about 5% to 10% of patients with tuberculosis progress from infection to active disease ( an immunosuppression often is responsible. ) secondary tuberculosis. often is associated with old age, poverty, and crowded living conditions …… in the apex of the lungs but may spread to many different sites typically, a low-grade fever, malaise, anorexia, weight loss, and night sweats. With pulmonary progression, a productive cough develops, often with hemoptysis or chest pain Progressive tuberculosis may lead to a wasting syndrome Extrapulmonary tuberculosis Any organ system may be involved, including the lymphatic system, skin, skeletal system, central nervous system, kidneys, and gastrointestinal tract.

Oral Tuberculosis uncommon, with most cases appearing as a chronic painless ulcer. Less frequent presentations include ……… nodular, granular, or (rarely) firm leukoplakic areas. Most of the lesions represent secondary pulmonary lesions infection from the initial

Primary oral tuberculosis without pulmonary involvement is rare usually involves the gingiva, mucobuccal fold, and areas of inflammation adjacent to teeth or in extraction sites. Usually in children and adolescent

secondary oral lesions are mostly present on the tongue, palate, and lip

Area of granularity and ulceration of the lower alveolar ridge and floor of mouth

ORAL TUBERCULOSIS Manifestation of TB in Oral and paraoral region include: 1. Oral ulcer 2. Tuberculous Osteomyielitis 3. Scorfula 4. Rarely Leukoplakia 5. Tuberculous Gingivitis 6. Tuberculoma at root apex of a Nonvital tooth

The chronic ulcerative form is the most common of these oral lesions the differential diagnoses Malignancies sarcoidosis syphilis aphthous lesion mycotic infection traumatic injury.

TUBERCULOSIS CASEOUS NECROSIS CLASS SLIDE (837(

TUBERCULOSIS CLASS SLIDE (837(

1 -Langhans giant cell 2 -Epitheloid cells 2 1

1 -Langhans giant cell