Trisomy 12 chronic lymphocytic leukemia expresses a unique

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Trisomy 12 chronic lymphocytic leukemia expresses a unique set of activated and targetable pathways

Trisomy 12 chronic lymphocytic leukemia expresses a unique set of activated and targetable pathways by Lynne V. Abruzzo, Carmen D. Herling, George A. Calin, Christopher Oakes, Lynn L. Barron, Haley E. Banks, Vikram Katju, Michael J. Keating, and Kevin R. Coombes haematol Volume 103(12): 2069 -2078 November 30, 2018 © 2018 by Ferrata Storti Foundation

Patients’ characteristics of the discovery set. Lynne V. Abruzzo et al. Haematologica 2018; 103:

Patients’ characteristics of the discovery set. Lynne V. Abruzzo et al. Haematologica 2018; 103: 2069 -2078 © 2018 by Ferrata Storti Foundation

Patients’ characteristics of the validation set. Lynne V. Abruzzo et al. Haematologica 2018; 103:

Patients’ characteristics of the validation set. Lynne V. Abruzzo et al. Haematologica 2018; 103: 2069 -2078 © 2018 by Ferrata Storti Foundation

Kaplan Meier plots stratified by cytogenetic subtype. Lynne V. Abruzzo et al. Haematologica 2018;

Kaplan Meier plots stratified by cytogenetic subtype. Lynne V. Abruzzo et al. Haematologica 2018; 103: 2069 -2078 © 2018 by Ferrata Storti Foundation

Results of two-way clustering according to cytogenetic subtype using the genes found to be

Results of two-way clustering according to cytogenetic subtype using the genes found to be differentially expressed. Lynne V. Abruzzo et al. Haematologica 2018; 103: 2069 -2078 © 2018 by Ferrata Storti Foundation

Ingenuity Pathway Analysis of differentially-regulated canonical pathways. Lynne V. Abruzzo et al. Haematologica 2018;

Ingenuity Pathway Analysis of differentially-regulated canonical pathways. Lynne V. Abruzzo et al. Haematologica 2018; 103: 2069 -2078 © 2018 by Ferrata Storti Foundation

Construction of a specific trisomy 12 (+12) CLL gene expression network. Lynne V. Abruzzo

Construction of a specific trisomy 12 (+12) CLL gene expression network. Lynne V. Abruzzo et al. Haematologica 2018; 103: 2069 -2078 © 2018 by Ferrata Storti Foundation