Triose phosphate dehydrogenase Phosphoglucoisomerase Phosphofructokinase Hexokinase Pyrvate Aldolase

解糖系の酵素 Triose phosphate dehydrogenase Phosphoglucoisomerase Phosphofructokinase Hexokinase Pyrvate Aldolase Enolase kinase Phosphoglyceromutase Phosphoglycerokinase グルコース グリセルアルデヒド3 -リン酸 ピルビン酸

乳酸デヒドロゲナーゼ 1 51 101 151 201 251 301 1 ATLKDKLIGH VDVMEDKLKG QEGESRLNLV SGLPMHRIIG WSGMNVAGVS AIGLSVADLA SNIVKMKLKP 11 LATSQEPRSY EMMDLQHGSL QRNVNIFKFI SGCNLDSARF LKELHPELGT ETIMKNLCRV DEEQQLQKSA 21 NKITVVGVGA FLHTAKIVSG IPDIVKHSPD RYLMGERLGV DKDKENWKKL HPVSTMVKDF TTLWDIQKDL 31 VGMACAISIL KDYSVSAGSK CIILVVSNPV HSSSCHGWVI HKDVVDSAYE YGIKNDVFLS KF 41 MKDLADEVAL LVVITAGARQ DVLTYVAWKL GEHGDSSVPV VIKLKGYTSW LPCVLDNHGI 50 100 150 200 250 300 水色のアミノ酸でNADを保持し、193番 目のHisがプロトンアクセプターとして働 く（from dogfish muscle）。

17β-hydroxysteroid dehydrogenase 1 51 101 151 201 251 1 MKFLLDILLL LTAYEFAKLK YSSAKKVKAE TTKAFLPAMT DELAALQITG LTEQKMIFIP 11 LPLLIVCSLE SKLVLWDINK IGDVSILVNN KNNHGHIVTV VKTTCLCPNF SSIAFLTTLE 21 SFVKLFIPKR HGLEETAAKC AGVVYTSDLF ASAAGHVSVP VNTGFIKNPS RILPERFLAV 31 RKSVTGEIVL KGLGAKVHTF ATQDPQIEKT FLLAYCSSKF TSLGPTLEPE LKRKISVKFD 41 ITGAGHGIGR VVDCSNREDI FEVNVLAHFW AAVGFHKTLT EVVNRLMHGI AVIGYKMKAQ 50 100 150 200 250 300 黄色いアミノ酸はシグナル、水色のアミ ノ酸でNADを保持し、185番目のTyrが プロトンアクセプターとして働く（ヒト）。

17β-steroid dehydrogenase

αグロビンの構造 1 16 31 46 61 76 91 106 121 136 1 Val Lys Arg Phe Lys Met Leu Val Leu 2 Leu Val Met Asp Val Pro Arg Val His Thr 3 Ser Gly Phe Leu Ala Asn Val Thr Ala Ser 4 Pro Ala Leu Ser Asp Ala Asp Leu Ser Lys 5 Ala His Ser His Ala Leu Pro Ala Leu Tyr 6 Asp Ala Phe Gly Leu Ser Val Ala Asp Arg 7 Lys Gly Pro Ser Thr Ala Asn His Lys 8 Thr Glu Thr Ala Asn Leu Phe 9 Asn Tyr Thr Gln Ala Ser Lys Pro Leu 10 Val Gly Lys Val Asp Leu Ala 11 Lys Ala Thr Lys Ala Leu Glu Ser 12 Ala Glu Tyr Gly His Ser Phe Val 13 Ala Phe His Val Ala His Thr Ser 14 Trp Leu Pro Gly Asp His Cys Pro Thr 15 Gly 15 Glu 30 His 45 Lys 60 Asp 75 Lys 90 Leu 105 Ala 120 Val 135

βグロビンの構造 1 16 31 46 61 76 91 106 121 136 1 Val Gly Leu Gly Lys Ala Leu Glu Gly 2 His Lys Leu Asp Ala His Gly Phe Val 3 Leu Val Leu His Leu Cys Asn Thr Ala 4 Thr Asn Val Ser Gly Asp Val Pro Asn 5 Pro Val Tyr Thr Lys Asn Lys Leu Pro Ala 6 Glu Asp Pro Lys Leu Val Leu 7 Glu Trp Asp Val Lys His Cys Gln Ala 8 Lys Val Thr Ala Leu Gly Val Ala His 9 Ser Gly Gln Val Gly Thr Asp Leu Ala Lys 10 Ala Gly Arg Met Ala Phe Pro Ala Tyr 11 Val Glu Phe Gly Phe Ala Glu His Gln His 12 Thr Ala Phe Asn Ser Thr Asn His Lys 13 Ala Leu Glu Pro Asp Leu Phe Val 14 Leu Gly Ser Lys Gly Ser Arg Gly Val 15 Trp 15 Arg 30 Phe 45 Val 60 Leu 75 Glu 90 Leu 105 Lys 120 Ala 135

ホルモン・インシュリン 膵臓に存在するランゲルハンス島(膵 島)のβ細胞から分泌されるペプチドホ ルモン（ヒト）。 1 16 31 46 61 76 91 106 1 Met Leu Cys Arg Leu Ser Ile Glu 2 Ala Trp Gly Gln Leu Val Asn 3 Leu Gly Ser Phe Val Gln Glu Tyr 4 Trp Pro His Phe Gly Pro Gln Cys 5 Met Asp Leu Tyr Gln Leu Cys Asn 6 Arg Pro Val Thr Val Ala Cys 7 Leu Ala Glu Pro Glu Leu Thr 8 Leu Ala Lys Leu Glu Ser 9 Pro Ala Leu Thr Gly Ile 10 11 12 Leu Ala Phe Val Asn Tyr Leu Val Arg Glu Gly Pro Ser Leu Gln Cys Ser Leu 13 Leu Gln Cys Ala Gly Lys Tyr 14 15 Leu Ala His Leu Gly Glu Asp Ala Gly Arg Gly Gln Leu 15 30 45 60 75 90 105

インシュリン受容体 1 61 121 181 241 301 361 421 481 541 601 661 721 781 841 901 961 1021 1081 1141 1201 1261 1321 1381 1 MGTGGRRGAA QILLMFKTRP VIFEMVHLKE ECGDICPGTA GNCSQPDDPT CHQYVIHNNK TVINGSLIIN EIGNYSFYAL RNDIALKTNG NVTEFDGQDA DERRTYGAKS RQAEDSELFE KELEESSFRK PNTSSTSVPT SARTMPEAKA SRKHFALERG PLIFVFLFSV EKITLLRELG FTCHHVVRLL AEIADGMAYL RWMAPESLKD CPERVTDLMR FEDMENVPLD PS 11 AAPLLVAVAA EDFRDLSFPK LGLYNLMNIT KGKTNCPATV KCVACRNFYL CIPECPSGYT IRGGNNLAAE DNQNLRQLWD DKASCENELL CGSNSWTVVD DIIYVQTDAT LDYCLKGLKL TFEDYLHNVV SPEEHRPFEK DDIVGPVTHE CRLRGLSPGN VIGSIYLFLR QGSFGMVYEG GVVSKGQPTL NAKKFVHRDL GVFTTSSDMW MCWQFNPKMR RSSHCQREEA 21 LLLGAAGHLY LIMITDYLLL RGSVRIEKNN INGQFVERCW DGRCVETCPP MNSSNLLCTP LEANLGLIEE WSKHNLTTTQ KFSYIRTSFD IDPPLRSNDP NPSVPLDPIS PSRTWSPPFE FVPRKTSSGT VVNKESLVIS IFENNVVHLM YSVRIRATSL KRQPDGPLGP NARDIIKGEA VVMELMAHGD AARNCMVAHD SFGVVLWEIT PTFLEIVNLL GGRDGGSSLG 31 PGEVCPGMDI FRVYGLESLK ELCYLATIDW THSHCQKVCP PYYHFQDWRC CLGPCPKVCH ISGYLKIRRS GKLFFHYNPK KILLRWEPYW KSQNHPGWLM VSNSSSQIIL SEDSQKHNQS GAEDPRPSRK GLRHFTGYRI WQEPKEPNGL AGNGSWTEPT LYASSNPEYL ETRVAVKTVN LKSYLRSLRP FTVKIGDFGM SLAEQPYQGL KDDLHPSFPE FKRSYEEHIP 41 RNNLTRLHEL DLFPNLTVIR SRILDSVEDN TICKSHGCTA VNFSFCQDLH LLEGEKTIDS YALVSLSFFR LCLSEIHKME PPDFRDLLGF RGLKPWTQYA KWKPPSDPNG EYEDSAGECC RRSLGDVGNV ELQACNQDTP IVLYEVSYRR YFYVTDYLDV SASDVFPCSV ESASLRERIE EAENNPGRPP TRDIYETDYY SNEQVLKFVM VSFFHSEENK YTHMNGGKKN 51 ENCSVIEGHL GSRLFFNYAL YIVLNKDDNE EGLCCHSECL HKCKNSRRQG VTSAQELRGC KLRLIRGETL EVSGTKGRQE MLFYKEAPYQ IFVKTLVTFS NITHYLVFWE SCPKTDSQIL TVAVPTVAAF EERCSVAAYV YGDEELHLCV PSNIAKIIIG YVPDEWEVSR FLNEASVMKG PTLQEMIQMA RKGGKGLLPV DGGYLDQPDN APESEELEME GRILTLPRSN 60 120 180 240 300 360 420 480 540 600 660 720 780 840 900 960 1020 1080 1140 1200 1260 1320 1380

G-アクチン ATP PDB 2 BTF G-actin PDB 2 BTF Actin monomer with bound ATP G-actin

運動神経の興奮から 滑り込みまで http: //entochem. tamu. edu/Muscle. Struc. Contractswf/index. html http: //highered. mcgraw-hill. com/sites/0072495855/ student_view 0/chapter 10/ animation__action_potentials_and_muscle_contraction. html