TRIGGERFISH Glaucoma Monitoring System BME 181 Brittany M

TRIGGERFISH Glaucoma Monitoring System BME 181 Brittany M. Alphonse Biomedical Engineering

Table of Contents Glaucoma Current Glaucoma Monitoring Systems Triggerfish Glaucoma Monitoring System Triggerfish System Components Benefits

Glaucoma Progressive and Irreversible Disease leads to blindness fluid accumulates in eye high levels of liquid inside eye Diameter of cornea changes Deterioration of Optic Nerve Asymptomatic Contributor of disease: frequent changes in pressure over the span of a day high peaks in levels during night 40+ years of age 4% of population is affected

Current Glaucoma Monitoring Systems Measures static intraocular pressure Single Snapshots in Time Monitoring in Overnight Sleep Labs taken during the day when pressure is lowest cumbersome expensive Frequent Punctual Measurements affects intraocular pressure checks pressure peaks

Triggerfish System Created by SENSIMED First of its Kind on the market constant reading device Safety Approval in Europe last year Expected U. S. Food and Drug Administration Approval in late 2011 Non-Invasive Continuous Monitoring System Measures Intraocular Pressure up to 24 hours Does Not Interfere with Normal Vision Constant Reading for Fraction of Price

Triggerfish System Components Sensor and Processor Disposable Contact Lens MEMS Sensor soft hydrophilic silicone sensor and microprocessor on outer edge strain gauge monitors diameter change in cornea Telemetry Microprocessor Processes level changes transmits to receiver

Components Continued Antenna Circular Antenna taped around the eye Sends Energy to Sensor Receives Measurement Information Connected to Portable Recorder thin flexible data cable

Components Continued Recorder/ Receiver Battery Powered Stores Measured Information Wirelessly Uploads Information Worn Around Neck Software Ophthalmologist Receives Information Visualize Intraocular Pressure Profile

Benefits of Triggerfish System Improved Understanding of Pressure Change pressure during day versus night More Efficient Personalized Drug Delivery and Treatment Adapt Treatment dependent on changing conditions Sensor is Placed Outside of Vision Field Early Diagnosis and Treatment

References for Pictures http: //www. sensimed. ch/S-Trig-benefits. htm http: //www. technologyreview. com/business/24 931/page 1/ http: //www. sensimed. ch/S-Trig-solution. htm