Translation from nucleic acid language to amino acid

  • Slides: 18
Download presentation
Translation from nucleic acid language to amino acid language to PROTEIN language AP Biology

Translation from nucleic acid language to amino acid language to PROTEIN language AP Biology https: //learn. genetics. utah. edu/content/basics/firefly/

How does m. RNA code for proteins? DNA TACGCACATTTACGCGG 4 ATCG The ORDER of

How does m. RNA code for proteins? DNA TACGCACATTTACGCGG 4 ATCG The ORDER of the nucleotide bases!!!!!! m. RNA AUGCGUGUAAAUGCGCC 4 AUCG Amino acid chain forms protein Met Arg Val Asn Ala Cys Ala 20 AP Biology How can you code for 20 amino acids with only 4 nucleotide bases (A, U, G, C)?

m. RNA codes for proteins in triplets DNA TACGCACATTTACGCGG codon m. RNA AUGCGUGUAAAUGCGCC ?

m. RNA codes for proteins in triplets DNA TACGCACATTTACGCGG codon m. RNA AUGCGUGUAAAUGCGCC ? protein AP Biology Amino acid Met Arg Val Asn Ala Cys Ala

The code n Code for ALL life! strongest support for a common origin for

The code n Code for ALL life! strongest support for a common origin for all life u n Code is redundant several codons for each amino acid u 3 rd base “wobble” use M-RNA Why isuthe u wobble good? n Start codon u u n AP Biology AUG methionine Stop codons u UGA, UAG The wobble base allows room for MUTATIONS

AP Biology

AP Biology

How are the codons matched to amino acids? DNA 3 5 5 3 TACGCACATTTACGCGG

How are the codons matched to amino acids? DNA 3 5 5 3 TACGCACATTTACGCGG m. RNA AUGCGUGUAAAUGCGCC 3 codon 5 UAC t. RNA amino acid GCA anti-codon CAU Met Arg Val Polypeptide chain Peptide bond AP Biology https: //highered. mheducation. com/sites/9834092339/student_view 0/chapter 15/protein_synthesis. html

a a From gene to protein nucleus cytoplasm The STRUCTURE and FUNCTION of the

a a From gene to protein nucleus cytoplasm The STRUCTURE and FUNCTION of the protein depends on the order of the amino acid sequences DNA transcription m. RNA a a translation a a a protein a a a a ribosome trait AP Biology

Ribosomes n n Make proteins Structure ribosomal RNA (r. RNA) u 2 subunits u

Ribosomes n n Make proteins Structure ribosomal RNA (r. RNA) u 2 subunits u large n small n n Role is to facilitate coupling of t. RNA anticodon to m. RNA codon http: //lab. concord. org/embeddable. html#interactives/sam/DNA-toproteins/4 -mutations. json AP Biology http: //learn. genetics. utah. edu/content/basics/transcribe/ E P A

RNA polymerase DNA Can you tell the story? amino acids exon intron t. RNA

RNA polymerase DNA Can you tell the story? amino acids exon intron t. RNA pre-m. RNA mature m. RNA large ribosomal subunit 5' 3' Protein: polypeptide chain t. RNA small ribosomal subunit AP Biology ribosome

Protein processing AP Biology

Protein processing AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology

AP Biology