Transgenic Animals Introduction Techniques to develop transgenic animals

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Transgenic Animals Introduction

Transgenic Animals Introduction

Techniques to develop transgenic animals �Started in the 1970, s and continued to improve.

Techniques to develop transgenic animals �Started in the 1970, s and continued to improve. �Become important tools for biomedical research �Economical way to produce many human substances such as hormones �In the future may help with organ procurement with transgenic organs decreasing the shortage of human organs for transplantation

Transgenic animal studies are helping to set the stage for gene therapy in humans

Transgenic animal studies are helping to set the stage for gene therapy in humans �In regards to human organ rejection; Scientist have developed ways to hide some of the markers on pig organs so the human immune system does not recognize the pig organ as foreign.

Biotechnology is a collection of scientific techniques �Use living cells and molecules to make

Biotechnology is a collection of scientific techniques �Use living cells and molecules to make products & solve problems �By using animals, plants and bacteria biotechnology allows us to enhance our health, our environment and our food supply

History �For thousands of years humans have conducted selective breeding to improve our livestock

History �For thousands of years humans have conducted selective breeding to improve our livestock �Controlled plant pollination to produce better crops �Microorganisms to bake bread �Brew beer �Make cheese

DNA & Biotechnology Transferring specific genes from one species to another �Allows for the

DNA & Biotechnology Transferring specific genes from one species to another �Allows for the production of microorganisms to produce human hormones: ex: insulin for diabetes �Improve livestock and crops

Transgenic organisms defined �Organisms which contain other species genes within their chromosomes �First transgenic

Transgenic organisms defined �Organisms which contain other species genes within their chromosomes �First transgenic organisms were bacteria; the simplest forms of life �First studied by molecular biologist �Advantages: �Reproduce quickly by cell division called (mitosis) �Easy to grow in Laboratory setting.

Pharmacy settings �Produce human proteins such as insulin for diabetes �Human growth hormones for

Pharmacy settings �Produce human proteins such as insulin for diabetes �Human growth hormones for those humans deficient �Interferon's for immunity, antiviral and possible treatment of certain cancer anticancer abilities

Potential of using transgenic techniques in animals can lead to: �Models for human disease

Potential of using transgenic techniques in animals can lead to: �Models for human disease �Improve the quality and health of livestock �Research and development of pharmaceuticals �Source of organs for humans with lesser chance of rejection by humans immune system