Toxicology Laboratory Updates Dr Fiona Couper State Toxicologist

Toxicology Laboratory Updates Dr. Fiona Couper, State Toxicologist Brian Capron, Supervisor/Forensic Toxicologist DRE In-Service, March 2010

General stats Year 2008 2009 Total # of DRE Cases 1327 1390 WSP 601 594 Allied 591 571 DRE Certifications 135 225 70 % % Males

# Drugs found per DRE case Year 2008 2009 No drugs detected 93 (8 %) 87 (7 %) 1 drug 442 (37 %) 470 (40 %) 2 drugs 249 (21 %) 256 (22 %) 3 drugs 200 (17 %) 180 (15 %) 4 drugs 117 (10 %) 100 (9 %) 5 drugs 51 (4 %) 47 (4 %) 6 drugs 30 (2. 5 %) 20 (2 %) 7 drugs 6 (<1 %) 5 (<1 %) 8 drugs 4 (<1 %) 0

Most frequent drugs – top 10 Freq 2009 # cases 2008 # cases 1 THC 331 (28%) THC 339 (28%) 2 Methamphet. 173 (15%) Methamphet. 168 (14%) 3 Alprazolam 144 (12%) Alprazolam 139 (12%) 4 Methadone 115 Oxycodone 131 5 Oxycodone 101 Methadone 122 6 Clonazepam 92 Diazepam 105 7 Diazepam 84 Clonazepam 90 8 Citalopram 78 Hydrocodone 89 9 Zolpidem 73 Morphine 83 10 Lorazepam 72 Carisoprodol 82 Note: Ethanol detected in 82 cases in 2009; 80 cases in 2008)

Most frequent drugs – top 20 Freq 2009 11 # cases 2008 # cases Morphine 57 Zolpidem 78 12 Carisoprodol 49 Citalopram 72 13 Temazepam 48 Cocaine 69 14 Hydrocodone 43 Lorazepam 64 15 Trazodone 40 Diphenhyd. 44 16 Oxazepam 39 Trazodone 36 17 Fluoxetine 32 Temazepam 34 18 Quetiapine 30 Fluoxetine 26 19 Diphenhyd. 29 Quetiapine 24 20 Cocaine 23 Oxazepam 22

Odds and Ends Drugs we do not routinely look for: Don’t routinely report out: Aripiprazole, GHB, Risperidone, Ziprasidone, LSD, Buprenorphine, Mushrooms Caffeine, EME, EDDP, nicotine Accreditation concerns We now have to confirm all drugs (i. e. 2 nd test) We now have strict Limits of Quantitation (LOQ’s)

Paperwork & Tox Reports Ø Paperwork Ø Ø Please send in Face Sheets and include any/all drugs Enter correct agency contact information Ø Proposed Ø Ø Ø changes to Tox Reports New LIMS system Will list all analyst(s) who did testing Will provide information on which drugs/classes we actually tested for, even if it’s negative