Thermal Endoscopy for Ear Nose Throat ENT Clinics

Thermal Endoscopy for Ear, Nose, Throat (ENT) Clinics 1

PROBLEM Poor contrast in ENT diagnostics 98. 8 million outpatient ENT visits annually Laryngopharyngeal reflux (LPR) ● Causes hoarseness and difficulty swallowing Often co-present in patients with. . . ● Sleep apnea (10 -25% American adults) ● Gastroesophageal reflux (18 -27% of American adults) Visual indicators of LPR are hard to distinguish and difficult to grade

OUR SOLUTION Thermography can see inflammation A thermal imaging adapter for ENT endoscopes Thermal camera to image surface temperature maps High temperature contrast for inflammation and perfusion

WHY NOW Thermal cameras are now cost effective Sensitive thermal camera is now the size of a smartphone camera module and priced off the shelf less than $300

TECHNOLOGY & IMPLEMENTATION Adapter What the adapter will do High contrast and accurate LPR diagnosis

MARKET OPPORTUNITY Market for ENT diagnostic devices 22 B USD market for ENT diagnostic devices Annual growth of 1. 6 B USD Imaging adapters capitalize on the existing prevalence of endoscopes Recapture existing value through add-on device

MARKET OPPORTUNITY Entering the market Exit: Demonstration of a high contrast thermographic adapter to retrofit a widely used endoscope will justify medical device company licensure and development of our IP, to develop a customized and specific adapter to their endoscope

COMPETITIVE LANDSCAPE

COMPETITIVE LANDSCAPE Thermal Imaging Increases contrast from visual light Reduces need for secondary scans (e. g. MRI, CT) Non-invasive No radiation Stand-alone system Fluorescence imaging Visual Light Endoscope Filtering Techniques (i. e. narrow-band imaging)

PROJECT PLAN TO EXIT