The Salivary Glands Introduction Three major paired salivary

The Salivary Glands 4. In addition, 600 -1, 000 minor salivary glands line the

The Salivary Glands Embryology The major salivary glands develop from the 6 th-8 th

The Salivary Glands However, the Parotid gland is the last to become encapsulated, after

The Salivary Glands The other major salivary glands do NOT have intraparenchymal lymph nodes.

The Salivary Glands During development of the glands, autonomic nervous system involvement is crucial;

The Salivary Glands Parotid Gland: It is the largest salivary gland. Averaging 5. 8

The Salivary Glands It is irregular, wedge shaped, and unilobular. It has been described

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The Salivary Glands Introduction Three major, paired salivary glands produce the majority of saliva: 1. Parotid 2. Submandibular 3. Sublingual 12/24/2021 1

The Salivary Glands 4. In addition, 600 -1, 000 minor salivary glands line the mouth vestibule, oral cavity proper and oropharynx, contributing a small portion of total salivary production. 12/24/2021 2

The Salivary Glands Embryology The major salivary glands develop from the 6 th-8 th weeks of gestation as outpouchings of oral ectoderm into the surrounding Mesenchyme. The parotid anlage develops first, growing in a posterior direction as the facial nerve. 12/24/2021 3

The Salivary Glands However, the Parotid gland is the last to become encapsulated, after the lymphatics develop, resulting in its unique anatomy with: Entrapment of lymphatics in the parenchyma of the gland Furthermore, salivary epithelial cells are often included within these lymph nodes. 12/24/2021 4

The Salivary Glands The other major salivary glands do NOT have intraparenchymal lymph nodes. The Minor Salivary Glands Arise From: Oral Ectoderm, Nasopharyngeal Endoderm They develop after the major salivary glands 12/24/2021 5

The Salivary Glands During development of the glands, autonomic nervous system involvement is crucial; Sympathetic nerve stimulation leads to Acinar Differentiation, while Parasympathetic Stimulation is needed for Overall Glandular Growth. 12/24/2021 6

The Salivary Glands Parotid Gland: It is the largest salivary gland. Averaging 5. 8 cm in the craniocaudal dimension, and 3. 4 cm in the ventral-dorsal dimension. Average weight of a Parotid gland is 14. 28 g. 12/24/2021 7

The Salivary Glands It is irregular, wedge shaped, and unilobular. It has been described as having 5 processes (3 superficial and 2 deep), thus making it very difficult to surgically removal all parotid tissue. 12/24/2021 8

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