The Salivary Glands Introduction Three major paired salivary
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The Salivary Glands Introduction Three major, paired salivary glands produce the majority of saliva: 1. Parotid 2. Submandibular 3. Sublingual 12/24/2021 1
The Salivary Glands 4. In addition, 600 -1, 000 minor salivary glands line the mouth vestibule, oral cavity proper and oropharynx, contributing a small portion of total salivary production. 12/24/2021 2
The Salivary Glands Embryology The major salivary glands develop from the 6 th-8 th weeks of gestation as outpouchings of oral ectoderm into the surrounding Mesenchyme. The parotid anlage develops first, growing in a posterior direction as the facial nerve. 12/24/2021 3
The Salivary Glands However, the Parotid gland is the last to become encapsulated, after the lymphatics develop, resulting in its unique anatomy with: Entrapment of lymphatics in the parenchyma of the gland Furthermore, salivary epithelial cells are often included within these lymph nodes. 12/24/2021 4
The Salivary Glands The other major salivary glands do NOT have intraparenchymal lymph nodes. The Minor Salivary Glands Arise From: Oral Ectoderm, Nasopharyngeal Endoderm They develop after the major salivary glands 12/24/2021 5
The Salivary Glands During development of the glands, autonomic nervous system involvement is crucial; Sympathetic nerve stimulation leads to Acinar Differentiation, while Parasympathetic Stimulation is needed for Overall Glandular Growth. 12/24/2021 6
The Salivary Glands Parotid Gland: It is the largest salivary gland. Averaging 5. 8 cm in the craniocaudal dimension, and 3. 4 cm in the ventral-dorsal dimension. Average weight of a Parotid gland is 14. 28 g. 12/24/2021 7
The Salivary Glands It is irregular, wedge shaped, and unilobular. It has been described as having 5 processes (3 superficial and 2 deep), thus making it very difficult to surgically removal all parotid tissue. 12/24/2021 8
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