The role of CD 44 in fetal and

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The role of CD 44 in fetal and adult hematopoietic stem cell regulation by

The role of CD 44 in fetal and adult hematopoietic stem cell regulation by Huimin Cao, Shen Y. Heazlewood, Brenda Williams, Daniela Cardozo, Julie Nigro, Ana Oteiza, and Susan K. Nilsson haematol Volume 101(1): 26 -37 December 31, 2015 © 2016 by Ferrata Storti Foundation

CD 44 expression by stem and progenitor cells during development. Huimin Cao et al.

CD 44 expression by stem and progenitor cells during development. Huimin Cao et al. Haematologica 2016; 101: 26 -37 © 2016 by Ferrata Storti Foundation

The incidence and content of HSC and progenitors in adult bone marrow. Huimin Cao

The incidence and content of HSC and progenitors in adult bone marrow. Huimin Cao et al. Haematologica 2016; 101: 26 -37 © 2016 by Ferrata Storti Foundation

The incidence and content of HSC in fetal and newborn hematopoietic organs. Huimin Cao

The incidence and content of HSC in fetal and newborn hematopoietic organs. Huimin Cao et al. Haematologica 2016; 101: 26 -37 © 2016 by Ferrata Storti Foundation

The role of CD 44 in FL HSC homing and SDF-1α expression in fetal

The role of CD 44 in FL HSC homing and SDF-1α expression in fetal tissue. Huimin Cao et al. Haematologica 2016; 101: 26 -37 © 2016 by Ferrata Storti Foundation

CD 44 is critical in adult HSC homing to BM and lodgment in the

CD 44 is critical in adult HSC homing to BM and lodgment in the endosteal region. Huimin Cao et al. Haematologica 2016; 101: 26 -37 © 2016 by Ferrata Storti Foundation

CD 44 on adult BM LSK cells has a functional role in supporting stem

CD 44 on adult BM LSK cells has a functional role in supporting stem and progenitor engraftment. Huimin Cao et al. Haematologica 2016; 101: 26 -37 © 2016 by Ferrata Storti Foundation

Neonatal CD 44−/− stem cell pool has equivalent numbers of long-term multi-lineage reconstituting HSC

Neonatal CD 44−/− stem cell pool has equivalent numbers of long-term multi-lineage reconstituting HSC but higher long-term engraftment potential compared to WT counterparts. Huimin Cao et al. Haematologica 2016; 101: 26 -37 © 2016 by Ferrata Storti Foundation

Schematic presentation summarizing the role of CD 44 in fetal and adult hematopoiesis. Huimin

Schematic presentation summarizing the role of CD 44 in fetal and adult hematopoiesis. Huimin Cao et al. Haematologica 2016; 101: 26 -37 © 2016 by Ferrata Storti Foundation