The Nephron Rhymes with Efron but isnt Efron

The Nephron • Filtering cells of the kidney • Over 1 million per kidney!! • Most in cortex • Some extend from cortex to medulla • Produce urine Copyright © 2009 Pearson Education, Inc. , publishing as Benjamin Cummings

The Nephron Copyright © 2009 Pearson Education, Inc. , publishing as Benjamin Cummings

Renal Corpuscle 2 parts 1. Glomerulus (part of the blood flow) - high pressure, porous capillary bed - allow solute-rich fluid to pass from blood -into glomerular capsule - under high pressure - forces materials smaller than proteins into the Bowman’s Capsule 2. Bowman’s capsule Copyright © 2009 Pearson Education, Inc. , publishing as Benjamin Cummings

Blood Vessels of the Nephron and Kidney Glomerulus § Fed and drained by arterioles § Afferent arteriole—arises from tiny branches of the renal artery, brings blood to the nephron § Efferent arteriole— receives blood from the nephron See page 520 figure 15. 2 c Copyright © 2009 Pearson Education, Inc. , publishing as Benjamin Cummings

Blood Vessels of the Nephron and Kidney § Efferent arteriole moves out of the Bowman’s capsule and becomes the peritubular capillaries § Peritubular capillaries surround the nephron tubule (PCT, Loop of Henle, DCT) § Reabsorption occurs here § Peritubular capillaries drain into venules and eventually branch into the renal vein Copyright © 2009 Pearson Education, Inc. , publishing as Benjamin Cummings

Parts of the Nephron Bowman’s Capsule § 1 st part of the nephron §

Renal Tube § Extending from Bowman’s capsule § For absorption of various materials back into the peritubular capillaries § Contain microvilli § 3 parts 1. Proximal convoluted tubule (PCT) 2. Loop of Henle Bowman’s capsule 3. Distal convoluted tubule (DCT) Copyright © 2009 Pearson Education, Inc. , publishing as Benjamin Cummings

Collecting Duct (collecting tubule) § Receives urine from multiple nephrons § Many collecting ducts run through the medullary pyramids to calyx and finally renal pelvis Copyright © 2009 Pearson Education, Inc. , publishing as Benjamin Cummings