The impact of cyclin D 1 m RNA

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The impact of cyclin D 1 m. RNA isoforms, morphology and p 53 in

The impact of cyclin D 1 m. RNA isoforms, morphology and p 53 in mantle cell lymphoma: p 53 alterations and blastoid morphology are strong predictors of a high proliferation index by Julia Slotta-Huspenina, Ina Koch, Laurence de Leval, Gisela Keller, Margit Klier, Karin Bink, Marcus Kremer, Mark Raffeld, Falko Fend, and Leticia Quintanilla. Martinez haematol Volume 97(9): 1422 -1430 September 5, 2012 © 2012 by Ferrata Storti Foundation

Blastoid (A, C, E) and classic MCL (B, D). Julia Slotta-Huspenina et al. Haematologica

Blastoid (A, C, E) and classic MCL (B, D). Julia Slotta-Huspenina et al. Haematologica 2012; 97: 14221430 © 2012 by Ferrata Storti Foundation

Scatter plots show the correlation between (A) proliferation index and blastoid morphology, (B) proliferation,

Scatter plots show the correlation between (A) proliferation index and blastoid morphology, (B) proliferation, morphological subtype and Cy. D 1 isoform expression (red diamonds: predominant Δ 3’UTR expression) and (C) proliferation, morphological subtype and p. . . Julia Slotta-Huspenina et al. Haematologica 2012; 97: 14221430 © 2012 by Ferrata Storti Foundation

Clinicopathological features of highly proliferative mantle cell lymphomas. Julia Slotta-Huspenina et al. Haematologica 2012;

Clinicopathological features of highly proliferative mantle cell lymphomas. Julia Slotta-Huspenina et al. Haematologica 2012; 97: 14221430 © 2012 by Ferrata Storti Foundation

Uni- and multivariate analyses of effects of prognostic factors on overall survival. Julia Slotta-Huspenina

Uni- and multivariate analyses of effects of prognostic factors on overall survival. Julia Slotta-Huspenina et al. Haematologica 2012; 97: 14221430 © 2012 by Ferrata Storti Foundation

Relationship between p 53 overexpression/mutation, Δ 3’UTR cyclin D 1 isoform expression, blastoid morphology

Relationship between p 53 overexpression/mutation, Δ 3’UTR cyclin D 1 isoform expression, blastoid morphology and the proliferation index measured by MIB-1 immunostaining. Julia Slotta-Huspenina et al. Haematologica 2012; 97: 14221430 © 2012 by Ferrata Storti Foundation

Overall survival analysis (Kaplan-Meier curves) of 51 MCL patients. Julia Slotta-Huspenina et al. Haematologica

Overall survival analysis (Kaplan-Meier curves) of 51 MCL patients. Julia Slotta-Huspenina et al. Haematologica 2012; 97: 14221430 © 2012 by Ferrata Storti Foundation

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