TESTICULAR TUMORS DENZ KAVGACI HALME HELN YILMAZ TNM

TESTICULAR TUMORS DENİZ KAVGACI HALİME HELİN YILMAZ

TNM STAGING American Joint Committee on Cancer (AJCC) T the extent of spread of the primary tumor to the tissues next to the testicle N number of lymph nodes affected M metastasis +/S indicates the serum level of tumor markers (specific for certain types of testicular cancers)

STAGING OF TESTICULAR CANCER • Stage I: tumor confined to the testis • Stage II: spread to regional lymph nodes • IIA: <2 cm in size or < 6 positive nodes • IIB: 2 -5 cm in size or > 6 positive nodes • IIC: large and bulky abdominal mass, usually > 5 -10 cm • Stage III: spread beyond retroperitoneal nodes or above diaphragm or visceral disease • Stage IV: hematogenous spread

TREATMENT OF SEMINOMAS Low grade (stage I and IIA) Radical inguinal orchiectomy Surveillance RT or single agent carboplatin High grade (stage >IIA) Radical inguinal orchiectomy RPLND RT and/or CT

NON-SEMINOMATOUS GERM CELL TUMOR Management of men with NSGCT stage I depends on the presence of factors that present an increased risk of relapse: - Lymphovascular invasion - Predominance of an embryonal carcinoma component - A T 3 or T 4 primary tumor

NSGCT TREATMENT

REFERANCES www. uptodate. com www. medscape. com www. cancer. net THANK YOU…