TAKE HOME MESSAGES Hb A 1 c hoe

TAKE HOME MESSAGES

Hb. A 1 c: hoe goed waren we en zijn we geworden? Jaar Afwijking Intralab Target CV Interlab CV 1993 ---- 5. 2% 22. 0% 1999 +0. 3% 4. 9% 11. 2% 2002 -0. 1% 3. 4% 8. 5% 2003 -0. 2% 2. 9% 6. 9% 2004 +0. 1% 2. 6% 4. 8% Compliment aan de Labs en Manufacturers Bron: C. W Weykamp

Glucose (Combi Algemene Chemie) mol/L Gebruikte methodes Aantal GDH 14 GOD 40 HK Ronde 2008. 1 140 Overall GDH GOD HK Concentratie monster 2 3, 9 4, 0 3, 9 Tussenlab CV in % 3, 0 4, 0 2, 7 3, 1 10, 4 10, 6 10, 4 2, 9 2, 6 2, 5 2, 9 16, 9 17, 2 16, 9 16, 8 2, 7 3, 3 2, 6 2, 7 Concentratie monster 1 Tussenlab CV in % Concentratie monster 4 Tussenlab CV in %

Microalbumine (Combi Urine) Gebruikte methodes mg/L Ronde 2008. 1 Aantal INA 19 ITA 128 Overall INA ITA 3, 5 3, 8 3, 4 Tussenlab CV in % 34, 3 21, 1 35, 3 Concentratie monster B 10, 9 12, 1 10, 7 Tussenlab CV in % 20, 2 9, 1 21, 5 Concentratie monster E 25 25, 3 25 Tussenlab CV in % 8, 8 7, 9 8, 8 Concentratie monster F

Standardization in Laboratory Medicine: are the times changing?

Manufacturer & directive 98/79/EC on IVD-MD & JCTLM Traceability chain EQA provider / SKML chemistry section: post-market vigilance of analytical performance tools: harmonizers / trueness controls Clinical chemist in case of excessive bias: temporary (re)calibration tools: matrix-based reference materials CLUE = commutability

Standardization in Laboratory Medicine: the times have changed!

En wat Bokito lukte, zal ons ook lukken…. ……eens